BR9908622A - Composição farmacêutica à base de progesterona natural de sìntese e de estradiol, e seu processo de preparo - Google Patents

Composição farmacêutica à base de progesterona natural de sìntese e de estradiol, e seu processo de preparo

Info

Publication number
BR9908622A
BR9908622A BR9908622-0A BR9908622A BR9908622A BR 9908622 A BR9908622 A BR 9908622A BR 9908622 A BR9908622 A BR 9908622A BR 9908622 A BR9908622 A BR 9908622A
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
estradiol
preparation process
composition based
synthetic progesterone
Prior art date
Application number
BR9908622-0A
Other languages
English (en)
Inventor
Benoit Agnus
Antoine Besins
Original Assignee
Besins Iscovesco Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Besins Iscovesco Lab filed Critical Besins Iscovesco Lab
Publication of BR9908622A publication Critical patent/BR9908622A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)

Abstract

Patente de Invenção: <B>"COMPOSIçãO FARMACêUTICA à BASE DE PROGESTERONA NATURAL DE SìNTESE E DE ESTRADIOL, E SEU PROCESSO DE PREPARO"<D>. A presente invenção refere-se a uma composição farmacêutica à base de progesterona natural de síntese e de estradiol que se apresenta sob a forma de comprimido, caracterizada pelo fato de apresentar um tempo de desagregação inferior a 15 minutos, de preferência inferior a 10 minutos e mais preferencialmente ainda inferior a 5 minutos.
BR9908622-0A 1998-03-09 1999-03-08 Composição farmacêutica à base de progesterona natural de sìntese e de estradiol, e seu processo de preparo BR9908622A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9802830A FR2775599B1 (fr) 1998-03-09 1998-03-09 Composition pharmaceutique a base de progesterone naturelle de synthese et d'oestradiol et son procede de preparation
PCT/FR1999/000515 WO1999045932A1 (fr) 1998-03-09 1999-03-08 Composition pharmaceutique a base de progesterone naturelle de synthese et d'oestradiol et son procede de preparation

Publications (1)

Publication Number Publication Date
BR9908622A true BR9908622A (pt) 2000-11-14

Family

ID=9523802

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9908622-0A BR9908622A (pt) 1998-03-09 1999-03-08 Composição farmacêutica à base de progesterona natural de sìntese e de estradiol, e seu processo de preparo

Country Status (13)

Country Link
US (1) US6656929B1 (pt)
EP (1) EP1061929B1 (pt)
KR (1) KR20010034573A (pt)
AT (1) ATE293979T1 (pt)
AU (1) AU3259099A (pt)
BR (1) BR9908622A (pt)
CA (1) CA2323696C (pt)
DE (1) DE69924987T2 (pt)
DK (1) DK1061929T3 (pt)
ES (1) ES2246578T3 (pt)
FR (1) FR2775599B1 (pt)
PT (1) PT1061929E (pt)
WO (1) WO1999045932A1 (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544553B1 (en) 1999-12-28 2003-04-08 Watson Pharmaceuticals, Inc. Dosage forms and methods for oral delivery of progesterone
FR2821555B1 (fr) 2001-03-01 2003-05-16 Besins Int Lab Progestatif co-micronise avec un tensioactif, composition pharmaceutique le comprenant, leurs procedes de fabrication et leurs utilisations
US20110312927A1 (en) * 2010-06-18 2011-12-22 Satish Kumar Nachaegari Progesterone Containing Oral Dosage Forms and Related Methods
US9375437B2 (en) 2010-06-18 2016-06-28 Lipocine Inc. Progesterone containing oral dosage forms and kits
US8951996B2 (en) 2011-07-28 2015-02-10 Lipocine Inc. 17-hydroxyprogesterone ester-containing oral compositions and related methods
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
JP6285866B2 (ja) 2011-11-23 2018-02-28 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． 天然複合ホルモン補充製剤および療法
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
KR20170005819A (ko) 2014-05-22 2017-01-16 쎄러퓨틱스엠디, 인코퍼레이티드 천연 복합 호르몬 대체 제형 및 요법
RU2016141135A (ru) 2014-07-29 2018-08-28 Терапьютиксмд, Инк. Трансдермальный крем
EP3310359A4 (en) 2015-06-22 2019-04-03 Lipocine Inc. ORAL COMPOSITIONS CONTAINING 17-HYDROXYPROGESTERONE ESTER AND METHODS RELATING THERETO
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
WO2017173071A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2399243A2 (fr) * 1974-04-23 1979-03-02 Aries Robert Perfectionnements aux procedes, dispositifs et produits pour l'implantation d'hormones destinees a favoriser la croissance des animaux d'embouche
US4755386A (en) * 1986-01-22 1988-07-05 Schering Corporation Buccal formulation
US5073374A (en) * 1988-11-30 1991-12-17 Schering Corporation Fast dissolving buccal tablet
DK95093D0 (da) * 1993-08-20 1993-08-20 Novo Nordisk As Farmaceutisk formulering indeholdende et hormon
DE4429374C1 (de) * 1994-08-12 1996-02-01 Jenapharm Gmbh Pharmazeutische Präparate zur Kontrazeption/Hormonsubstitution mit biogener Estrogenkomponente
DE19718012C1 (de) * 1997-04-29 1998-10-08 Jenapharm Gmbh Verfahren zur Herstellung peroral anwendbarer fester Arzneiformen mit gesteuerter Wirkstoffabgabe

Also Published As

Publication number Publication date
DE69924987D1 (de) 2005-06-02
DK1061929T3 (da) 2005-08-29
AU3259099A (en) 1999-09-27
CA2323696C (fr) 2010-04-27
EP1061929A1 (fr) 2000-12-27
ATE293979T1 (de) 2005-05-15
PT1061929E (pt) 2005-09-30
ES2246578T3 (es) 2006-02-16
US6656929B1 (en) 2003-12-02
DE69924987T2 (de) 2006-06-08
FR2775599A1 (fr) 1999-09-10
KR20010034573A (ko) 2001-04-25
EP1061929B1 (fr) 2005-04-27
WO1999045932A1 (fr) 1999-09-16
FR2775599B1 (fr) 2001-08-17
CA2323696A1 (fr) 1999-09-16

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO, UMA VEZ QUE INFRINGE OS ARTIGOS 8O E 13 DA LEI 9279/96

B12B Appeal against refusal [chapter 12.2 patent gazette]
B08L Patent application lapsed because of non payment of annual fee [chapter 8.12 patent gazette]

Free format text: REFERENTE AO NAO RECOLHIMENTO DAS 13A, 14A E 15A ANUIDADES.

B15K Others concerning applications: alteration of classification

Ipc: A61K 31/57 (2006.01), A61K 9/20 (2006.01), A01B 71

B08I Publication cancelled [chapter 8.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 8.12 NA RPI NO 2256 DE 01/04/2014 POR TER SIDO INDEVIDA.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 13A ATE A 21A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2602 DE 17-11-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.