ATE293979T1 - Pharmazeutische zusammensetzungen enthaltend syntethisch natürliche progesteron und estradiol und verfahren zur herstellung derselben - Google Patents

Pharmazeutische zusammensetzungen enthaltend syntethisch natürliche progesteron und estradiol und verfahren zur herstellung derselben

Info

Publication number
ATE293979T1
ATE293979T1 AT99939161T AT99939161T ATE293979T1 AT E293979 T1 ATE293979 T1 AT E293979T1 AT 99939161 T AT99939161 T AT 99939161T AT 99939161 T AT99939161 T AT 99939161T AT E293979 T1 ATE293979 T1 AT E293979T1
Authority
AT
Austria
Prior art keywords
syntethically
estradiol
producing
pharmaceutical compositions
same
Prior art date
Application number
AT99939161T
Other languages
English (en)
Inventor
Benoit Agnus
Antoine Besins
Original Assignee
Besins Iscovesco Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Besins Iscovesco Lab filed Critical Besins Iscovesco Lab
Application granted granted Critical
Publication of ATE293979T1 publication Critical patent/ATE293979T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
AT99939161T 1998-03-09 1999-03-08 Pharmazeutische zusammensetzungen enthaltend syntethisch natürliche progesteron und estradiol und verfahren zur herstellung derselben ATE293979T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9802830A FR2775599B1 (fr) 1998-03-09 1998-03-09 Composition pharmaceutique a base de progesterone naturelle de synthese et d'oestradiol et son procede de preparation
PCT/FR1999/000515 WO1999045932A1 (fr) 1998-03-09 1999-03-08 Composition pharmaceutique a base de progesterone naturelle de synthese et d'oestradiol et son procede de preparation

Publications (1)

Publication Number Publication Date
ATE293979T1 true ATE293979T1 (de) 2005-05-15

Family

ID=9523802

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99939161T ATE293979T1 (de) 1998-03-09 1999-03-08 Pharmazeutische zusammensetzungen enthaltend syntethisch natürliche progesteron und estradiol und verfahren zur herstellung derselben

Country Status (13)

Country Link
US (1) US6656929B1 (de)
EP (1) EP1061929B1 (de)
KR (1) KR20010034573A (de)
AT (1) ATE293979T1 (de)
AU (1) AU3259099A (de)
BR (1) BR9908622A (de)
CA (1) CA2323696C (de)
DE (1) DE69924987T2 (de)
DK (1) DK1061929T3 (de)
ES (1) ES2246578T3 (de)
FR (1) FR2775599B1 (de)
PT (1) PT1061929E (de)
WO (1) WO1999045932A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544553B1 (en) 1999-12-28 2003-04-08 Watson Pharmaceuticals, Inc. Dosage forms and methods for oral delivery of progesterone
FR2821555B1 (fr) 2001-03-01 2003-05-16 Besins Int Lab Progestatif co-micronise avec un tensioactif, composition pharmaceutique le comprenant, leurs procedes de fabrication et leurs utilisations
US20110312927A1 (en) * 2010-06-18 2011-12-22 Satish Kumar Nachaegari Progesterone Containing Oral Dosage Forms and Related Methods
US9375437B2 (en) 2010-06-18 2016-06-28 Lipocine Inc. Progesterone containing oral dosage forms and kits
US8951996B2 (en) 2011-07-28 2015-02-10 Lipocine Inc. 17-hydroxyprogesterone ester-containing oral compositions and related methods
RS62297B1 (sr) 2011-11-23 2021-09-30 Therapeuticsmd Inc Prirodne kombinovane hormonske supstitucione formulacije i terapije
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
JP2017516768A (ja) 2014-05-22 2017-06-22 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． 天然の併用ホルモン補充療法剤及び療法
RU2016141135A (ru) 2014-07-29 2018-08-28 Терапьютиксмд, Инк. Трансдермальный крем
CN107847506A (zh) 2015-06-22 2018-03-27 来普卡公司 含17‑羟基孕酮酯的口服组合物和相关方法
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
RU2018133932A (ru) 2016-04-01 2020-05-12 Терапьютиксмд, Инк. Фармацевтическая композиция стероидного гормона
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2399243A2 (fr) * 1974-04-23 1979-03-02 Aries Robert Perfectionnements aux procedes, dispositifs et produits pour l'implantation d'hormones destinees a favoriser la croissance des animaux d'embouche
US4755386A (en) * 1986-01-22 1988-07-05 Schering Corporation Buccal formulation
US5073374A (en) * 1988-11-30 1991-12-17 Schering Corporation Fast dissolving buccal tablet
DK95093D0 (da) * 1993-08-20 1993-08-20 Novo Nordisk As Farmaceutisk formulering indeholdende et hormon
DE4429374C1 (de) * 1994-08-12 1996-02-01 Jenapharm Gmbh Pharmazeutische Präparate zur Kontrazeption/Hormonsubstitution mit biogener Estrogenkomponente
DE19718012C1 (de) * 1997-04-29 1998-10-08 Jenapharm Gmbh Verfahren zur Herstellung peroral anwendbarer fester Arzneiformen mit gesteuerter Wirkstoffabgabe

Also Published As

Publication number Publication date
BR9908622A (pt) 2000-11-14
AU3259099A (en) 1999-09-27
PT1061929E (pt) 2005-09-30
DE69924987T2 (de) 2006-06-08
EP1061929A1 (de) 2000-12-27
FR2775599B1 (fr) 2001-08-17
DE69924987D1 (de) 2005-06-02
CA2323696A1 (fr) 1999-09-16
WO1999045932A1 (fr) 1999-09-16
DK1061929T3 (da) 2005-08-29
EP1061929B1 (de) 2005-04-27
ES2246578T3 (es) 2006-02-16
CA2323696C (fr) 2010-04-27
US6656929B1 (en) 2003-12-02
KR20010034573A (ko) 2001-04-25
FR2775599A1 (fr) 1999-09-10

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