BR9907884A - Composição de vacina, processos para gerar uma resposta imune em um antìgeno pneumocócico, para aumentar resposta de ifn-gama em uma vacina pneumocócica, e para gerar anticorpos de fixação complementar para uma resposta protetora a um patógeno, composição imunogênica, e, processo para gerar uma resposta imune em um antìgeno meningocócico - Google Patents
Composição de vacina, processos para gerar uma resposta imune em um antìgeno pneumocócico, para aumentar resposta de ifn-gama em uma vacina pneumocócica, e para gerar anticorpos de fixação complementar para uma resposta protetora a um patógeno, composição imunogênica, e, processo para gerar uma resposta imune em um antìgeno meningocócicoInfo
- Publication number
- BR9907884A BR9907884A BR9907884-8A BR9907884A BR9907884A BR 9907884 A BR9907884 A BR 9907884A BR 9907884 A BR9907884 A BR 9907884A BR 9907884 A BR9907884 A BR 9907884A
- Authority
- BR
- Brazil
- Prior art keywords
- generating
- antigen
- response
- immune response
- pneumococcal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
- A61K2039/55538—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7452898P | 1998-02-12 | 1998-02-12 | |
PCT/US1999/002847 WO1999040936A2 (en) | 1998-02-12 | 1999-02-10 | Pneumococcal and meningococcal vaccines formulated with interleukin-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9907884A true BR9907884A (pt) | 2000-10-24 |
Family
ID=22120049
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9907884-8A BR9907884A (pt) | 1998-02-12 | 1999-02-10 | Composição de vacina, processos para gerar uma resposta imune em um antìgeno pneumocócico, para aumentar resposta de ifn-gama em uma vacina pneumocócica, e para gerar anticorpos de fixação complementar para uma resposta protetora a um patógeno, composição imunogênica, e, processo para gerar uma resposta imune em um antìgeno meningocócico |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1053015A2 (ja) |
JP (3) | JP2002502882A (ja) |
KR (1) | KR100585408B1 (ja) |
CN (1) | CN1200730C (ja) |
AU (1) | AU759391B2 (ja) |
BR (1) | BR9907884A (ja) |
CA (1) | CA2320223A1 (ja) |
IL (2) | IL137809A0 (ja) |
WO (1) | WO1999040936A2 (ja) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL137809A0 (en) * | 1998-02-12 | 2001-10-31 | American Cyanamid Co | Pneumococcal and meningococcal vaccines formulated with interleukin-12 |
US6908757B1 (en) | 1998-03-26 | 2005-06-21 | The Procter & Gamble Company | Serine protease variants having amino acid deletions and substitutions |
MXPA02000840A (es) | 1999-07-22 | 2002-07-30 | Procter & Gamble | Variantes de proteasa de subtilisina que tienen substituciones de aminoacidos en regiones de epitopes definidas. |
BR0012694A (pt) | 1999-07-22 | 2002-04-09 | Procter & Gamble | Conjugado de protease, composição de limpeza e composição de tratamento pessoal |
US6946128B1 (en) | 1999-07-22 | 2005-09-20 | The Procter & Gamble Company | Protease conjugates having sterically protected epitope regions |
BR0012693A (pt) | 1999-07-22 | 2002-04-09 | Procter & Gamble | Variante, de protease tipo subtilisina; composição de limpeza; e composição de cuidado pessoal |
DE60335477D1 (de) | 2002-10-11 | 2011-02-03 | Novartis Vaccines & Diagnostic | Polypeptidimpstoffe zum breiten schutz gegen hypervirulente meningokokken-linien |
DK1587537T3 (da) | 2003-01-30 | 2012-07-16 | Novartis Ag | Injicerbare vacciner mod multiple meningococ-serogrupper |
CA2540896C (en) | 2003-10-02 | 2015-06-02 | Chiron Srl | Liquid vaccines for multiple meningococcal serogroups |
GB0500787D0 (en) | 2005-01-14 | 2005-02-23 | Chiron Srl | Integration of meningococcal conjugate vaccination |
GB0409745D0 (en) | 2004-04-30 | 2004-06-09 | Chiron Srl | Compositions including unconjugated carrier proteins |
DK1740217T3 (da) | 2004-04-30 | 2011-09-26 | Novartis Ag | Meningokok-konjugat-vaccination |
GB0410866D0 (en) | 2004-05-14 | 2004-06-16 | Chiron Srl | Haemophilius influenzae |
GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
GB0502095D0 (en) | 2005-02-01 | 2005-03-09 | Chiron Srl | Conjugation of streptococcal capsular saccharides |
WO2006089264A2 (en) | 2005-02-18 | 2006-08-24 | Novartis Vaccines And Diagnostics Inc. | Proteins and nucleic acids from meningitis/sepsis-associated escherichia coli |
NZ599345A (en) | 2005-02-18 | 2013-07-26 | Novartis Vaccines & Diagnostic | Immunogens from uropathogenic Escherichia Coli |
SI1868645T1 (sl) * | 2005-04-08 | 2012-04-30 | Wyeth Llc | Večvalentni pnevmokokni sestavek konjugata polisaharid-protein |
US7955605B2 (en) * | 2005-04-08 | 2011-06-07 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
US20090074712A1 (en) * | 2005-05-19 | 2009-03-19 | Compton | Methods for Treatment and Prevention of Infection |
GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
AU2007285484B2 (en) | 2006-08-16 | 2013-05-02 | Novartis Ag | Immunogens from uropathogenic Escherichia coli |
GB0713880D0 (en) | 2007-07-17 | 2007-08-29 | Novartis Ag | Conjugate purification |
GB0714963D0 (en) | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
GB0818453D0 (en) | 2008-10-08 | 2008-11-12 | Novartis Ag | Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom |
NZ587382A (en) | 2008-02-21 | 2012-01-12 | Novartis Ag | Meningococcal fhbp polypeptides |
US8568732B2 (en) | 2009-03-06 | 2013-10-29 | Novartis Ag | Chlamydia antigens |
CN109248313B (zh) | 2009-04-14 | 2023-01-17 | 葛兰素史密丝克莱恩生物有限公司 | 用于免疫接种以抵御金黄色葡萄球菌的组合物 |
MX2012000395A (es) | 2009-07-07 | 2012-02-28 | Novartis Ag | Inmunogenos conservados de escherichia coli. |
MX2012000734A (es) | 2009-07-16 | 2012-01-27 | Novartis Ag | Inmunogenos destoxificados de escherichia coli. |
NZ598458A (en) | 2009-08-27 | 2014-03-28 | Novartis Ag | Hybrid polypeptides including meningococcal fhbp sequences |
SG178904A1 (en) | 2009-09-10 | 2012-04-27 | Novartis Ag | Combination vaccines against respiratory tract diseases |
GB0917002D0 (en) | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Improved shigella blebs |
GB0917003D0 (en) | 2009-09-28 | 2009-11-11 | Novartis Vaccines Inst For Global Health Srl | Purification of bacterial vesicles |
AU2010302344A1 (en) | 2009-09-30 | 2012-04-26 | Novartis Ag | Expression of meningococcal fhbp polypeptides |
AU2010352695B2 (en) | 2009-09-30 | 2014-08-21 | Glaxosmithkline Biologicals S.A. | Conjugation of Staphylococcus aureus type 5 and type 8 capsular polysaccharides |
GB0918392D0 (en) | 2009-10-20 | 2009-12-02 | Novartis Ag | Diagnostic and therapeutic methods |
JP5960055B2 (ja) | 2009-10-27 | 2016-08-02 | ノバルティス アーゲー | 改変髄膜炎菌fHBPポリペプチド |
GB0919690D0 (en) | 2009-11-10 | 2009-12-23 | Guy S And St Thomas S Nhs Foun | compositions for immunising against staphylococcus aureus |
ES2707778T3 (es) | 2009-12-30 | 2019-04-05 | Glaxosmithkline Biologicals Sa | Inmunógenos polisacáridos conjugados con proteínas portadoras de E. coli |
GB201003333D0 (en) | 2010-02-26 | 2010-04-14 | Novartis Ag | Immunogenic proteins and compositions |
GB201005625D0 (en) | 2010-04-01 | 2010-05-19 | Novartis Ag | Immunogenic proteins and compositions |
WO2011127316A1 (en) | 2010-04-07 | 2011-10-13 | Novartis Ag | Method for generating a parvovirus b19 virus-like particle |
GB201009861D0 (en) | 2010-06-11 | 2010-07-21 | Novartis Ag | OMV vaccines |
EP3153578A1 (en) | 2010-07-06 | 2017-04-12 | Novartis Ag | Norovirus derived immunogenic compositions and methods |
GB201101665D0 (en) | 2011-01-31 | 2011-03-16 | Novartis Ag | Immunogenic compositions |
GB201017519D0 (en) | 2010-10-15 | 2010-12-01 | Novartis Vaccines Inst For Global Health S R L | Vaccines |
WO2012072769A1 (en) | 2010-12-01 | 2012-06-07 | Novartis Ag | Pneumococcal rrgb epitopes and clade combinations |
CA2860331A1 (en) | 2010-12-24 | 2012-06-28 | Novartis Ag | Compounds |
ES2687129T3 (es) | 2011-07-25 | 2018-10-23 | Glaxosmithkline Biologicals Sa | Composiciones y métodos para evaluar la inmunogenicidad funcional de vacunas contra parvovirus |
GB201114923D0 (en) | 2011-08-30 | 2011-10-12 | Novartis Ag | Immunogenic proteins and compositions |
WO2013038375A2 (en) | 2011-09-14 | 2013-03-21 | Novartis Ag | Methods for making saccharide-protein glycoconjugates |
US9511130B2 (en) | 2011-09-14 | 2016-12-06 | Glaxosmithkline Biologicals Sa | Escherichia coli vaccine combination |
KR20140101835A (ko) | 2011-12-08 | 2014-08-20 | 노파르티스 아게 | 클로스트리듐 디피실레 톡신-기반 백신 |
WO2013108272A2 (en) | 2012-01-20 | 2013-07-25 | International Centre For Genetic Engineering And Biotechnology | Blood stage malaria vaccine |
CA2865028A1 (en) | 2012-02-24 | 2013-08-29 | Novartis Ag | Pilus proteins and compositions |
US10279026B2 (en) | 2012-04-26 | 2019-05-07 | Glaxosmithkline Biologicals Sa | Antigens and antigen combinations |
EP2841096B1 (en) | 2012-04-26 | 2020-09-30 | GlaxoSmithKline Biologicals SA | Antigens and antigen combinations |
KR20150021933A (ko) | 2012-05-22 | 2015-03-03 | 노파르티스 아게 | 수막염구균 혈청군 x 포합체 |
RU2662970C2 (ru) | 2012-09-18 | 2018-07-31 | Новартис Аг | Везикулы наружной мембраны |
AU2013326584B2 (en) | 2012-10-02 | 2016-12-01 | Glaxosmithkline Biologicals Sa | Nonlinear saccharide conjugates |
RU2015106745A (ru) | 2012-10-03 | 2016-11-27 | Глэксосмитклайн Байолоджикалз Са | Иммуногенные композиции |
JP6340011B2 (ja) | 2012-11-30 | 2018-06-06 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | シュードモナス抗原および抗原の組み合わせ |
US9815886B2 (en) | 2014-10-28 | 2017-11-14 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
CN114544913B (zh) * | 2022-02-23 | 2024-04-09 | 沈阳建筑大学 | 一种土壤调查加密采样布点优化方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5153312A (en) * | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
CA2059693C (en) * | 1991-01-28 | 2003-08-19 | Peter J. Kniskern | Polysaccharide antigens from streptococcus pneumoniae |
CA2059692C (en) * | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Pneumoccoccal polysaccharide conjugate vaccine |
US5571515A (en) * | 1994-04-18 | 1996-11-05 | The Wistar Institute Of Anatomy & Biology | Compositions and methods for use of IL-12 as an adjuvant |
GB2303855B (en) * | 1994-07-01 | 1998-10-28 | Rican Limited | Helicobacter pylori antigenic protein preparation and immunoassays |
ATE322289T1 (de) * | 1994-10-05 | 2006-04-15 | Univ Vanderbilt | Interleukin-12 als adjuvans für paramyoxviridae impfstoffe |
GB9422990D0 (en) * | 1994-11-15 | 1995-01-04 | Cortecs Ltd | Immunogenic compositions |
US5866134A (en) * | 1995-03-24 | 1999-02-02 | Schering Corporation | Method for enhancing the antibody response to specific antigens with Interleukin-10 |
AU5507098A (en) * | 1995-12-19 | 1998-03-19 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Enhancement of dna immunization through the use of cytokines |
DK1015026T3 (da) * | 1996-05-31 | 2006-09-11 | Nat Univ Ireland Maynooth | IL-12 som en adjuvans til Bordetella pertussis-vacciner |
US6438586B1 (en) * | 1996-09-30 | 2002-08-20 | Emc Corporation | File transfer utility which employs an intermediate data storage system |
IL137809A0 (en) * | 1998-02-12 | 2001-10-31 | American Cyanamid Co | Pneumococcal and meningococcal vaccines formulated with interleukin-12 |
US6303114B1 (en) * | 1998-03-05 | 2001-10-16 | The Medical College Of Ohio | IL-12 enhancement of immune responses to T-independent antigens |
-
1999
- 1999-02-10 IL IL13780999A patent/IL137809A0/xx active IP Right Grant
- 1999-02-10 CA CA002320223A patent/CA2320223A1/en not_active Abandoned
- 1999-02-10 AU AU25965/99A patent/AU759391B2/en not_active Ceased
- 1999-02-10 KR KR1020007008806A patent/KR100585408B1/ko not_active IP Right Cessation
- 1999-02-10 CN CNB998038792A patent/CN1200730C/zh not_active Expired - Fee Related
- 1999-02-10 JP JP2000531187A patent/JP2002502882A/ja active Pending
- 1999-02-10 BR BR9907884-8A patent/BR9907884A/pt not_active IP Right Cessation
- 1999-02-10 EP EP99905924A patent/EP1053015A2/en not_active Withdrawn
- 1999-02-10 WO PCT/US1999/002847 patent/WO1999040936A2/en active IP Right Grant
-
2000
- 2000-08-10 IL IL137809A patent/IL137809A/en not_active IP Right Cessation
-
2009
- 2009-08-24 JP JP2009193167A patent/JP2010006827A/ja active Pending
-
2010
- 2010-06-24 JP JP2010144063A patent/JP2010265279A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IL137809A (en) | 2007-12-03 |
KR20010040898A (ko) | 2001-05-15 |
CN1292706A (zh) | 2001-04-25 |
CN1200730C (zh) | 2005-05-11 |
JP2002502882A (ja) | 2002-01-29 |
WO1999040936A2 (en) | 1999-08-19 |
JP2010265279A (ja) | 2010-11-25 |
AU2596599A (en) | 1999-08-30 |
AU759391B2 (en) | 2003-04-10 |
JP2010006827A (ja) | 2010-01-14 |
KR100585408B1 (ko) | 2006-06-01 |
CA2320223A1 (en) | 1999-08-19 |
IL137809A0 (en) | 2001-10-31 |
WO1999040936A3 (en) | 1999-10-28 |
EP1053015A2 (en) | 2000-11-22 |
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