BR9904800A - Test for the detection of infection by lyme disease, process to produce flarecombinant protein from transformed cell cultures, and flarecombinant protein. - Google Patents

Test for the detection of infection by lyme disease, process to produce flarecombinant protein from transformed cell cultures, and flarecombinant protein.

Info

Publication number
BR9904800A
BR9904800A BR9904800-0A BR9904800A BR9904800A BR 9904800 A BR9904800 A BR 9904800A BR 9904800 A BR9904800 A BR 9904800A BR 9904800 A BR9904800 A BR 9904800A
Authority
BR
Brazil
Prior art keywords
protein
flarecombinant
detection
lyme disease
cell cultures
Prior art date
Application number
BR9904800-0A
Other languages
Portuguese (pt)
Inventor
Robert D Gilmore Jr
Barbara J B Johnson
Original Assignee
Bio Merieux Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Merieux Inc filed Critical Bio Merieux Inc
Publication of BR9904800A publication Critical patent/BR9904800A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

"TESTE PARTA A DETECçãO DE INFECçãO POR DOENçA LYME, PROCESSO PARA PRODUZIR PROTEìNA FlaA RECOMBINANTE A PARTIR DE CULTURAS DE CéLULA TRANSFORMADAS, E, PROTEìNA FlaA RECOMBINANTE". A presente invenção provê composições e processos para imunoteste sorológico para a detecção de infecção por doença Lyme usando antígeno de protéina P37/FlaA recombinante e processos para produzir este antígeno de proteína."TEST DETECTION OF LYME DISEASE INFECTION, PROCESS TO PRODUCE RECOMBINANT FLA PROTEIN FROM TRANSFORMED CELL CULTURES, AND, RECOMBINANT FLA PROTEIN". The present invention provides compositions and processes for serological immunotest for the detection of Lyme disease infection using recombinant protein P37 / FlaA antigen and processes for producing this protein antigen.

BR9904800-0A 1998-01-08 1999-01-06 Test for the detection of infection by lyme disease, process to produce flarecombinant protein from transformed cell cultures, and flarecombinant protein. BR9904800A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US439598A 1998-01-08 1998-01-08
PCT/US1999/000196 WO1999035272A1 (en) 1998-01-08 1999-01-06 RECOMBINANT P37/FlaA AS A DIAGNOSTIC REAGENT

Publications (1)

Publication Number Publication Date
BR9904800A true BR9904800A (en) 2000-05-16

Family

ID=21710596

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9904800-0A BR9904800A (en) 1998-01-08 1999-01-06 Test for the detection of infection by lyme disease, process to produce flarecombinant protein from transformed cell cultures, and flarecombinant protein.

Country Status (9)

Country Link
US (1) US20040142399A1 (en)
EP (1) EP0963438A1 (en)
JP (1) JP2001516458A (en)
KR (1) KR20000076072A (en)
AU (1) AU747124B2 (en)
BR (1) BR9904800A (en)
CA (1) CA2283494A1 (en)
IL (1) IL131649A0 (en)
WO (1) WO1999035272A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100093100A1 (en) * 2007-01-12 2010-04-15 University Of Louisville Research Foundation, Inc. Profiling method useful for condition diagnosis and monitoring, composition screening, and therapeutic monitoring
AU2008206461B2 (en) * 2007-01-12 2013-08-15 University Of Louisville Research Foundation, Inc. Proteomic profiling method useful for condition diagnosis and monitoring, composition screening, and therapeutic monitoring
EP2274616A1 (en) * 2008-04-22 2011-01-19 The Research Foundation of State University of New York Borrelia burgdorferi cell envelope protein array
RU2622004C2 (en) * 2012-10-05 2017-06-08 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Methods of obtaining molecular structures containing antigenic epitopes of topical allergens and signal peptides with immunoregulatory properties
RU2514230C1 (en) * 2012-12-14 2014-04-27 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт биохимии" Сибирского отделения Российской академии медицинских наук (ФГБУ "НИИ биохимии" СО РАМН) Recombinant chimeric polypeptides, carrying epitopes of various immunodominant proteins of spirochaeta of borrelia burgdorferi sensu lato complex, and serum diagnostic technique for ixodic tick-borne borreliosis
SI3353551T1 (en) * 2015-09-25 2023-03-31 Qiagen Sciences, Llc Compositions and methods for diagnosing lyme disease and for predicting lyme disease spirochete elimination after treatment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4120345C5 (en) * 1991-06-19 2004-08-12 Arnold Prof. Dr.med. Vogt Protein fragments from the central region of the flagellin from Borrelia burgdorferi, suitable as antigens for the specific detection of antibodies and methods for their production
JP2000510339A (en) * 1996-05-08 2000-08-15 イエール ユニバーシティ B. expressed in vivo burgdorferi polypeptide

Also Published As

Publication number Publication date
EP0963438A1 (en) 1999-12-15
AU2213399A (en) 1999-07-26
WO1999035272A1 (en) 1999-07-15
JP2001516458A (en) 2001-09-25
CA2283494A1 (en) 1999-07-15
AU747124B2 (en) 2002-05-09
US20040142399A1 (en) 2004-07-22
KR20000076072A (en) 2000-12-26
IL131649A0 (en) 2001-01-28

Similar Documents

Publication Publication Date Title
Dietzschold et al. Biological characterization of human monoclonal antibodies to rabies virus
BR0114475A (en) Cell for the production of antibody composition
ATE364621T1 (en) HIV PEPTIDES
DE50014571D1 (en) VEHICLE PHARMAKA CONJUGATES
DE69836630D1 (en) HIGHLY SIMILAR RECIPE PROTEINS, RELATED REAGENTS AND METHODS
PT733069E (en) PURIFIED PRIMATE CTLA-8 ANTIGENS AND RELATED REAGENTS
BR9906927A (en) Neisseria meningitidis proteins
ATE549347T1 (en) MAMMAL GENES, AND ASSOCIATED REAGENTS, METHODS
BR9609521A (en) Connective tissue growth factor
ATE283289T1 (en) MONOCLONAL ANTIBODIES, ANTIGENS AND DIAGNOSIS AND THERAPY OF MALIGNANT DISEASES
SE9600406L (en) New compounds
DE60134136D1 (en) CYTOKIN RECEPTOR SUBUNITS PROTEINS FROM MAMMALS, ASSOCIATED REAGENTS AND METHODS
HUP0002176A2 (en) Prrsv antigenic sites identifying peptide sequences of prrs virus for use in vaccines or diagnostic assays
FI902143A0 (en) HIV-PEPTIDER, ARTIFICIELLA HIV-ANTIGENER OCH IMMUNOBESTAEMNINGSFOERPACKNINGAR.
ATE442439T1 (en) MELANOMA ANTIGENE P15 AND THEIR APPLICATION IN DIAGNOSTIC AND THERAPEUTIC PROCEDURES
CY1109093T1 (en) Mammalian Receptor Proteins, Related Reagents, and Related Methods
BR0110402A (en) Compounds
SE9401460D0 (en) Antigen / antibody specificity exhanger
SE8703225D0 (en) MONOCLONAL ANTIBODIES AND PEPTIDES USEFUL IN TREATING AND DIAGNOSING HIV INFECTIONS
BR9810907A (en) Monoclonal and polyclonal antibodies, peptide capable of generating an antibody, immunogenic agent, nucleotide sequence, pharmaceutical composition, use of at least one antibody, diagnostic kit, and process for preparing an immunogenic agent
BR9904800A (en) Test for the detection of infection by lyme disease, process to produce flarecombinant protein from transformed cell cultures, and flarecombinant protein.
BR0116686A (en) Silenced anti-cd28 Antibodies and usage
ATE353337T1 (en) ADHESIN FROM HELIOBACTER PYLORI, WHICH BINDS TO BLOOD GROUP ANTIGENS
WO1995020764A1 (en) Specific binding substances for antibodies and their use for immunoassays or vaccines
ATE472337T1 (en) PHARMACEUTICAL COMPOSITION OF F(AB) 2 FRAGMENTS OF ANTIBODIES AND METHOD FOR THE PRODUCTION THEREOF

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A,7A , 8A E 9A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1923 DE 13/11/2007.