BR9710377A - Gr-nulos de derivados de hexahidropirazina administr veis por via oral - Google Patents
Gr-nulos de derivados de hexahidropirazina administr veis por via oralInfo
- Publication number
- BR9710377A BR9710377A BR9710377A BR9710377A BR9710377A BR 9710377 A BR9710377 A BR 9710377A BR 9710377 A BR9710377 A BR 9710377A BR 9710377 A BR9710377 A BR 9710377A BR 9710377 A BR9710377 A BR 9710377A
- Authority
- BR
- Brazil
- Prior art keywords
- granules
- orally administered
- hexahydropyrazine derivatives
- hexahydropyrazine
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19628776A DE19628776A1 (de) | 1996-07-17 | 1996-07-17 | Oral applizierbare Granulate von Hexahydropyrazinderivaten |
PCT/EP1997/003537 WO1998003157A1 (de) | 1996-07-17 | 1997-07-04 | Oral applizierbare granulate von hexahydropyrazinderivaten |
Publications (2)
Publication Number | Publication Date |
---|---|
BR9710377A true BR9710377A (pt) | 1999-08-17 |
BR9710377B1 BR9710377B1 (pt) | 2011-10-18 |
Family
ID=7800044
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI9710377-2A BR9710377B1 (pt) | 1996-07-17 | 1997-07-04 | gránulos de praziquantel administráveis por via oral a gatos. |
Country Status (17)
Country | Link |
---|---|
US (1) | US6503536B2 (pt) |
EP (1) | EP0912167B1 (pt) |
JP (1) | JP4202422B2 (pt) |
KR (1) | KR100485149B1 (pt) |
CN (1) | CN1225579A (pt) |
AT (1) | ATE227565T1 (pt) |
AU (1) | AU711705B2 (pt) |
BR (1) | BR9710377B1 (pt) |
CA (1) | CA2260889C (pt) |
DE (2) | DE19628776A1 (pt) |
DK (1) | DK0912167T3 (pt) |
ES (1) | ES2183200T3 (pt) |
HU (1) | HUP9903180A3 (pt) |
NO (1) | NO325272B1 (pt) |
NZ (1) | NZ333745A (pt) |
PT (1) | PT912167E (pt) |
WO (1) | WO1998003157A1 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2767173T3 (es) * | 2002-08-13 | 2020-06-16 | Intervet Int Bv | Composiciones y proceso para administrar un aditivo |
US20040180034A1 (en) * | 2003-03-10 | 2004-09-16 | Lyn Hughes | Anthelmintic resinates and a method for their preparation |
US7396819B2 (en) * | 2003-08-08 | 2008-07-08 | Virbac Corporation | Anthelmintic formulations |
DE10358525A1 (de) | 2003-12-13 | 2005-07-07 | Bayer Healthcare Ag | Endoparasitizide Mittel zur topischen Applikation |
WO2005094210A2 (en) * | 2004-03-12 | 2005-10-13 | The Hartz Mountain Corporation | Multi-action anthelmintic formulations |
DE102005011779A1 (de) * | 2005-03-11 | 2006-09-14 | Bayer Healthcare Ag | Endoparasitizide Mittel |
DE102007026550A1 (de) | 2007-06-08 | 2008-12-11 | Bayer Healthcare Ag | Extrudate mit verbesserter Geschmacksmaskierung |
MD20170009A2 (ro) | 2012-02-06 | 2017-07-31 | Merial Limited | Compoziţii veterinare antiparazitare orale cu conţinut de agenţi activi cu acţiune sistemică, metode şi aplicări ale acestora |
CN109010296A (zh) | 2012-04-04 | 2018-12-18 | 英特维特国际股份有限公司 | 异噁唑啉化合物的固体口服药物组合物 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2362539C2 (de) | 1973-12-17 | 1986-05-07 | Merck Patent Gmbh, 6100 Darmstadt | 2-Acyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
US4447414A (en) * | 1982-12-21 | 1984-05-08 | Cutter Laboratories, Inc. | Carnivore anthelmintics |
DE3472678D1 (de) | 1983-07-18 | 1988-08-18 | Beecham Group Plc | Benzazepine and benzoxazepine derivatives |
DE3623321A1 (de) | 1986-07-11 | 1988-01-21 | Bayer Ag | Verfahren zur kontinuierlichen herstellung von sphaerischen granulaten |
FI101344B1 (fi) * | 1988-03-31 | 1998-06-15 | Tanabe Seiyaku Co | Menetelmä valmistaa valmiste, josta kontrolloidusti vapautuu farmaseuttisesti aktiivista ainetta |
CN1099973A (zh) * | 1993-09-08 | 1995-03-15 | 四川省医学科学院寄生虫病防治研究所 | 兽用驱虫药物复方制剂 |
AUPM969994A0 (en) | 1994-11-28 | 1994-12-22 | Virbac S.A. | Equine anthelmintic formulations |
-
1996
- 1996-07-17 DE DE19628776A patent/DE19628776A1/de not_active Withdrawn
-
1997
- 1997-07-04 AT AT97931773T patent/ATE227565T1/de not_active IP Right Cessation
- 1997-07-04 HU HU9903180A patent/HUP9903180A3/hu unknown
- 1997-07-04 WO PCT/EP1997/003537 patent/WO1998003157A1/de active IP Right Grant
- 1997-07-04 AU AU35413/97A patent/AU711705B2/en not_active Ceased
- 1997-07-04 DE DE59708723T patent/DE59708723D1/de not_active Expired - Lifetime
- 1997-07-04 NZ NZ333745A patent/NZ333745A/xx not_active IP Right Cessation
- 1997-07-04 PT PT97931773T patent/PT912167E/pt unknown
- 1997-07-04 CN CN97196483A patent/CN1225579A/zh active Pending
- 1997-07-04 KR KR10-1999-7000198A patent/KR100485149B1/ko not_active IP Right Cessation
- 1997-07-04 ES ES97931773T patent/ES2183200T3/es not_active Expired - Lifetime
- 1997-07-04 CA CA002260889A patent/CA2260889C/en not_active Expired - Fee Related
- 1997-07-04 JP JP50648498A patent/JP4202422B2/ja not_active Expired - Fee Related
- 1997-07-04 DK DK97931773T patent/DK0912167T3/da active
- 1997-07-04 US US09/214,858 patent/US6503536B2/en not_active Expired - Lifetime
- 1997-07-04 BR BRPI9710377-2A patent/BR9710377B1/pt not_active IP Right Cessation
- 1997-07-04 EP EP97931773A patent/EP0912167B1/de not_active Expired - Lifetime
-
1999
- 1999-01-14 NO NO19990157A patent/NO325272B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR20000067862A (ko) | 2000-11-25 |
AU3541397A (en) | 1998-02-10 |
CA2260889C (en) | 2007-09-11 |
ES2183200T3 (es) | 2003-03-16 |
KR100485149B1 (ko) | 2005-04-25 |
NO990157D0 (no) | 1999-01-14 |
NZ333745A (en) | 2000-10-27 |
JP2000515519A (ja) | 2000-11-21 |
DK0912167T3 (da) | 2003-03-10 |
CA2260889A1 (en) | 1998-01-29 |
US6503536B2 (en) | 2003-01-07 |
CN1225579A (zh) | 1999-08-11 |
US20010055598A1 (en) | 2001-12-27 |
EP0912167A1 (de) | 1999-05-06 |
PT912167E (pt) | 2003-03-31 |
NO325272B1 (no) | 2008-03-17 |
DE59708723D1 (de) | 2002-12-19 |
WO1998003157A1 (de) | 1998-01-29 |
AU711705B2 (en) | 1999-10-21 |
ATE227565T1 (de) | 2002-11-15 |
EP0912167B1 (de) | 2002-11-13 |
BR9710377B1 (pt) | 2011-10-18 |
JP4202422B2 (ja) | 2008-12-24 |
NO990157L (no) | 1999-01-14 |
HUP9903180A2 (hu) | 2000-04-28 |
DE19628776A1 (de) | 1998-01-22 |
HUP9903180A3 (en) | 2000-07-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFERIMENTO DO PRESENTE PEDIDO COM BASE NOS ARTS. 8O, 13 E 24 DA LPI 9279/96 |
|
B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
B25A | Requested transfer of rights approved |
Owner name: BAYER ANIMAL HEALTH GMBH (DE) Free format text: TRANSFERIDO DE: BAYER AKTIENGESELLSCHAFT |
|
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 18/10/2011, OBSERVADAS AS CONDICOES LEGAIS. |
|
B25A | Requested transfer of rights approved | ||
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time | ||
B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |