BR9611407A - Derivados de 1-arilsulfonila, aril(tio)carbonil-piridazino e métodos de preparação. - Google Patents

Derivados de 1-arilsulfonila, aril(tio)carbonil-piridazino e métodos de preparação.

Info

Publication number
BR9611407A
BR9611407A BR9611407-0A BR9611407A BR9611407A BR 9611407 A BR9611407 A BR 9611407A BR 9611407 A BR9611407 A BR 9611407A BR 9611407 A BR9611407 A BR 9611407A
Authority
BR
Brazil
Prior art keywords
derivatives
pyridazine
carbonyl
aryl
arylsulfonyl
Prior art date
Application number
BR9611407-0A
Other languages
English (en)
Inventor
Donald W Combs
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of BR9611407A publication Critical patent/BR9611407A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/36—Benzo-cinnolines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Rheumatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Patente de Invenção: <B>"DERIVADOS DE 1-ARILSULFONILA, ARIL(TIO)CARBONIL-PIRIDAZINO E MéTODOS DE PREPARAçãO"<D>. São descritos derivados de 1-arilsulfonila, arilcarbonila e aril(tio)carbonil piridazino e processos para a produção dos referidos derivados. Os novos derivados são compostos heterocíclicos não-esteroidais os quais agem como progestinas e/ou antiprogestinas seletivas tendo uma elevada afinidade in vitro para o receptor de progestina uterino, mamário ou ósseo. Como tais, os derivados heterocíclicos não-esteroidais são úteis em contracepção, menopausa, osteoporose ou endometriose.
BR9611407-0A 1995-11-06 1996-10-10 Derivados de 1-arilsulfonila, aril(tio)carbonil-piridazino e métodos de preparação. BR9611407A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US790095P 1995-11-06 1995-11-06
PCT/US1996/016227 WO1997017332A1 (en) 1995-11-06 1996-10-10 1-arylsulphonyl, aryl(thio)carbonyl pyridazino derivatives and methods of preparation

Publications (1)

Publication Number Publication Date
BR9611407A true BR9611407A (pt) 1999-12-28

Family

ID=21728709

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9611407-0A BR9611407A (pt) 1995-11-06 1996-10-10 Derivados de 1-arilsulfonila, aril(tio)carbonil-piridazino e métodos de preparação.

Country Status (17)

Country Link
JP (1) JP2000501073A (pt)
KR (1) KR100360614B1 (pt)
CN (1) CN1110485C (pt)
AU (1) AU704507B2 (pt)
BR (1) BR9611407A (pt)
CZ (1) CZ286789B6 (pt)
HU (1) HU225162B1 (pt)
IL (1) IL124320A (pt)
MX (1) MX9803605A (pt)
NO (1) NO310460B1 (pt)
NZ (1) NZ319979A (pt)
PL (1) PL185618B1 (pt)
RU (1) RU2175969C2 (pt)
TW (1) TW460467B (pt)
UA (1) UA48989C2 (pt)
WO (1) WO1997017332A1 (pt)
ZA (1) ZA969298B (pt)

Also Published As

Publication number Publication date
HUP0201305A2 (hu) 2002-12-28
AU704507B2 (en) 1999-04-22
CN1207091A (zh) 1999-02-03
AU7263796A (en) 1997-05-29
CN1110485C (zh) 2003-06-04
HU225162B1 (en) 2006-07-28
NO982030L (no) 1998-06-23
KR19990067340A (ko) 1999-08-16
PL326669A1 (en) 1998-10-12
RU2175969C2 (ru) 2001-11-20
CZ138098A3 (cs) 1998-09-16
WO1997017332A1 (en) 1997-05-15
NO310460B1 (no) 2001-07-09
NO982030D0 (no) 1998-05-05
CZ286789B6 (en) 2000-07-12
TW460467B (en) 2001-10-21
NZ319979A (en) 1999-11-29
JP2000501073A (ja) 2000-02-02
IL124320A (en) 2001-10-31
HUP0201305A3 (en) 2003-02-28
PL185618B1 (pl) 2003-06-30
IL124320A0 (en) 1998-12-06
KR100360614B1 (ko) 2003-06-02
ZA969298B (en) 1998-05-05
MX9803605A (es) 1998-09-30
UA48989C2 (uk) 2002-09-16

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Legal Events

Date Code Title Description
PC Transfer

Free format text: JOHNSON & JOHNSON (US)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO DE PATENTE DE ACORDO COM ART. 36O DA LPI