BR9605646A - Cloridrato cristalino de(r)-(-)-2{n-[4-(1,1-dióxido-3-oxo-2,3-dihidro-benzo tiazol-2-il)-butil]-aminometil}-cromano - Google Patents

Cloridrato cristalino de(r)-(-)-2{n-[4-(1,1-dióxido-3-oxo-2,3-dihidro-benzo tiazol-2-il)-butil]-aminometil}-cromano

Info

Publication number
BR9605646A
BR9605646A BR9605646A BR9605646A BR9605646A BR 9605646 A BR9605646 A BR 9605646A BR 9605646 A BR9605646 A BR 9605646A BR 9605646 A BR9605646 A BR 9605646A BR 9605646 A BR9605646 A BR 9605646A
Authority
BR
Brazil
Prior art keywords
aminomethyl
dihydro
oxo
butyl
dioxide
Prior art date
Application number
BR9605646A
Other languages
English (en)
Inventor
Alfons Grunenberg
Dietrich Siedel
Michael Conrad
Oliver Brehm
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of BR9605646A publication Critical patent/BR9605646A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
BR9605646A 1995-11-22 1996-11-21 Cloridrato cristalino de(r)-(-)-2{n-[4-(1,1-dióxido-3-oxo-2,3-dihidro-benzo tiazol-2-il)-butil]-aminometil}-cromano BR9605646A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19543478A DE19543478A1 (de) 1995-11-22 1995-11-22 Kristallines Hydrochlorid von {(R)-(-)-2- N-[4-(1,1-Dioxido-3-oxo-2,3-dihydrobenzisothiazol-2-yl)-buytl]-aminomethyl}-chroman

Publications (1)

Publication Number Publication Date
BR9605646A true BR9605646A (pt) 1998-08-18

Family

ID=7778081

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9605646A BR9605646A (pt) 1995-11-22 1996-11-21 Cloridrato cristalino de(r)-(-)-2{n-[4-(1,1-dióxido-3-oxo-2,3-dihidro-benzo tiazol-2-il)-butil]-aminometil}-cromano

Country Status (32)

Country Link
US (1) US5830908A (pt)
EP (1) EP0775704B1 (pt)
JP (1) JPH09143180A (pt)
KR (1) KR970027079A (pt)
CN (1) CN1086703C (pt)
AR (1) AR004961A1 (pt)
AT (1) ATE201872T1 (pt)
AU (1) AU712922B2 (pt)
BR (1) BR9605646A (pt)
CA (1) CA2190700A1 (pt)
CZ (1) CZ289730B6 (pt)
DE (2) DE19543478A1 (pt)
DK (1) DK0775704T3 (pt)
EE (1) EE9600183A (pt)
ES (1) ES2159342T3 (pt)
GR (1) GR3036505T3 (pt)
HU (1) HUP9603237A3 (pt)
IL (1) IL119647A (pt)
MX (1) MX9605741A (pt)
MY (1) MY132473A (pt)
NO (1) NO307340B1 (pt)
NZ (1) NZ299780A (pt)
PL (1) PL317090A1 (pt)
PT (1) PT775704E (pt)
RU (1) RU2181723C2 (pt)
SG (1) SG44989A1 (pt)
SI (1) SI0775704T1 (pt)
SK (1) SK150096A3 (pt)
TR (1) TR199600930A2 (pt)
TW (1) TW449595B (pt)
UA (1) UA45338C2 (pt)
ZA (1) ZA969753B (pt)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5854217A (en) * 1992-09-28 1998-12-29 Bearsden Bio, Inc. Allosteric modulators of the NMDA receptor and their use in the treatment of CNS disorders and enhancement of CNS function
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US7501426B2 (en) 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
DE102005035891A1 (de) * 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
CA2873524C (en) 2006-05-04 2018-02-20 Boehringer Ingelheim International Gmbh A polymeric form of 1-((4-methyl-quinazolin-2-yl)methyl)-3-7-(2-butyn-1-yl)-8-(3-(r)-aminopiperidin-1-yl)xanthine
PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
ES2733348T3 (es) * 2007-08-17 2019-11-28 Boehringer Ingelheim Int Derivados de purina para uso en el tratamiento de enfermedades relacionadas con FAP
PE20140960A1 (es) 2008-04-03 2014-08-15 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
PE20100156A1 (es) * 2008-06-03 2010-02-23 Boehringer Ingelheim Int Tratamiento de nafld
BRPI0916997A2 (pt) 2008-08-06 2020-12-15 Boehringer Ingelheim International Gmbh Inibidor de dpp-4 e seu uso
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
US20110190322A1 (en) * 2008-08-14 2011-08-04 Boehringer Ingelheim International Gmbh Purin derivatives for use in the treatment of fab-related diseases
CN102149407A (zh) 2008-09-10 2011-08-10 贝林格尔.英格海姆国际有限公司 治疗糖尿病和相关病症的组合疗法
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
BRPI0923121A2 (pt) 2008-12-23 2015-08-11 Boehringer Ingelheim Int Formas salinas de compostos orgânico
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
CN102753161A (zh) 2009-11-27 2012-10-24 贝林格尔.英格海姆国际有限公司 基因型糖尿病患者利用dpp-iv抑制剂例如利拉利汀的治疗
WO2011138421A1 (en) 2010-05-05 2011-11-10 Boehringer Ingelheim International Gmbh Combination therapy
EP3124041A1 (en) 2010-06-24 2017-02-01 Boehringer Ingelheim International GmbH Diabetes therapy
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
ES2713566T3 (es) 2011-07-15 2019-05-22 Boehringer Ingelheim Int Derivado de quinazolina dimérico sustituido, su preparación y su uso en composiciones farmacéuticas para el tratamiento de la diabetes de tipo I y II
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
WO2013171167A1 (en) 2012-05-14 2013-11-21 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
ES2950384T3 (es) 2014-02-28 2023-10-09 Boehringer Ingelheim Int Uso médico de un inhibidor de DPP-4
JP2019517542A (ja) 2016-06-10 2019-06-24 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング リナグリプチンおよびメトホルミンの組合せ

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300523A (en) * 1988-07-28 1994-04-05 Bayer Aktiengesellschaft Substituted aminomethyltetralins and their heterocyclic analogues
DE3901814A1 (de) 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE4138756A1 (de) * 1991-11-26 1993-05-27 Troponwerke Gmbh & Co Kg Kombination mit neuroprotektiver wirkung

Also Published As

Publication number Publication date
IL119647A0 (en) 1997-02-18
DE19543478A1 (de) 1997-05-28
PT775704E (pt) 2001-09-28
MX9605741A (es) 1997-05-31
NZ299780A (en) 1998-09-24
MY132473A (en) 2007-10-31
DE59607040D1 (de) 2001-07-12
GR3036505T3 (en) 2001-11-30
HUP9603237A3 (en) 1998-12-28
EP0775704B1 (de) 2001-06-06
ATE201872T1 (de) 2001-06-15
IL119647A (en) 1999-12-22
NO964950L (no) 1997-05-23
CZ289730B6 (cs) 2002-03-13
DK0775704T3 (da) 2001-07-23
TW449595B (en) 2001-08-11
CN1086703C (zh) 2002-06-26
RU2181723C2 (ru) 2002-04-27
CZ342896A3 (en) 1997-06-11
NO307340B1 (no) 2000-03-20
HUP9603237A2 (hu) 1998-01-28
ES2159342T3 (es) 2001-10-01
NO964950D0 (no) 1996-11-21
EP0775704A1 (de) 1997-05-28
SK150096A3 (en) 1997-08-06
KR970027079A (ko) 1997-06-24
PL317090A1 (en) 1997-05-26
AR004961A1 (es) 1999-04-07
JPH09143180A (ja) 1997-06-03
UA45338C2 (uk) 2002-04-15
SI0775704T1 (en) 2001-08-31
ZA969753B (en) 1997-03-25
HU9603237D0 (en) 1997-01-28
CA2190700A1 (en) 1997-05-23
SG44989A1 (en) 1997-12-19
US5830908A (en) 1998-11-03
AU7177296A (en) 1997-05-29
AU712922B2 (en) 1999-11-18
EE9600183A (et) 1997-06-16
TR199600930A2 (tr) 1997-06-21
CN1152574A (zh) 1997-06-25

Similar Documents

Publication Publication Date Title
BR9605646A (pt) Cloridrato cristalino de(r)-(-)-2{n-[4-(1,1-dióxido-3-oxo-2,3-dihidro-benzo tiazol-2-il)-butil]-aminometil}-cromano
NO965084D0 (no) N-[3(3-cyanopyrazol[1,5-aÅpyrimidin-7-yl)fenylÅ-N-etyl-acetamid
DE69630188D1 (de) Phacoemulsifikationshandstück, manschette und spitze
ATE318280T1 (de) Hydrophob modifizierte kammpolymere
NO986017D0 (no) N-[4-(Heteroarylmetyl)fenyl]-Heteroarylaminer
BRPI9810519B1 (pt) derivados de 4''-substituìdo-9-desoxo-9a-aza-9a-homoeritromicina a e composição farmacêutica compreendendo os mesmos.
DE59608798D1 (de) Endoparasitizide mittel
PT1000048E (pt) Derivados substituidos do 1,2,3,4-tetrahidronaftaleno
NO960884D0 (no) N-(3-benzofuranyl)urea-derivater
DZ2222A1 (fr) Dihydrates de mésylate de 5-(2-(4-(1,2-benzisothiazole-3-al)-1-pipérazinyl)éthyl)-6-chloro-1,3-dihydro-2h-indole-2-one.
NO20002686L (no) Forbedring av Peyronies sykdom
SV1996000004A (es) 2-(2-n-alcoxifenil)-purin-6-onas 9 sustituidas
DE60042585D1 (de) 3-Aza-6,8-dioxabicycloÄ3.2.1Üoctane und Analoga sowie diese enthaltende kombinatorische Bibliotheken
NO20003786D0 (no) Oftalmisk sammensetning
NO973508D0 (no) Antipsykotiske 4-(1H-indol-l-yl)-piperidinylderivater
PT790236E (pt) Pro-farmacos de 5-(2-(4-(1,2-benzisotiazol-3-il)-1-piperazinil)-etil-6-cloro-1,3-di-hidro-2h-indol-2-ona
ID21499A (id) Proses untuk memproduksi n-(4-fluorofenil)-n-(1-metiletil)-2-[(5-(trifluorometil)-1,3,4-tiadiazol-2-il)-oksi]-asetamida
DE69941245D1 (de) Kapazitiver sensor
NO20006350D0 (no) Derivater av 3-(2-okso-[1,3']bipyrrolidinyl-3-ylidenmetyl)- cephemer
DE59910240D1 (de) Kapazitiver Sensor
DE60033721D1 (de) Kosmetische Wasser-in-Öl-Emulsion
BR9611366A (pt) Processos e intermediarios para prearação a preparação de 3-(1-piperazinil)-1,2-benzisotiazol
NO20003145D0 (no) FremgangsmÕte for fremstilling av paroxetine-hydroklorid
DE69604645D1 (de) Chip des piezoelektrischen/elektrostriktiven types
UA3497S (uk) Печиво "пальчики"

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]