BR9503015A - Oligonucleotídeo composições terapêuticas e uso de uma composição - Google Patents

Oligonucleotídeo composições terapêuticas e uso de uma composição

Info

Publication number
BR9503015A
BR9503015A BR9503015A BR9503015A BR9503015A BR 9503015 A BR9503015 A BR 9503015A BR 9503015 A BR9503015 A BR 9503015A BR 9503015 A BR9503015 A BR 9503015A BR 9503015 A BR9503015 A BR 9503015A
Authority
BR
Brazil
Prior art keywords
composition
therapeutic compositions
oligonucleotide therapeutic
oligonucleotide
compositions
Prior art date
Application number
BR9503015A
Other languages
English (en)
Inventor
Soudhir Colote
Eduardo Pirotzky
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scras filed Critical Scras
Publication of BR9503015A publication Critical patent/BR9503015A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y205/00Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01029Geranylgeranyl diphosphate synthase (2.5.1.29)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
BR9503015A 1994-06-29 1995-06-29 Oligonucleotídeo composições terapêuticas e uso de uma composição BR9503015A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9413035A GB9413035D0 (en) 1994-06-29 1994-06-29 Antisense oligonucleeotides

Publications (1)

Publication Number Publication Date
BR9503015A true BR9503015A (pt) 1996-06-04

Family

ID=10757497

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9503015A BR9503015A (pt) 1994-06-29 1995-06-29 Oligonucleotídeo composições terapêuticas e uso de uma composição

Country Status (25)

Country Link
US (1) US5856461A (pt)
EP (1) EP0692535A1 (pt)
JP (1) JPH0851985A (pt)
KR (1) KR960000914A (pt)
CN (1) CN1124142A (pt)
AU (1) AU689887B2 (pt)
BR (1) BR9503015A (pt)
CA (1) CA2152233A1 (pt)
CZ (1) CZ291496B6 (pt)
DZ (1) DZ1903A1 (pt)
FI (1) FI953170A (pt)
FR (2) FR2721827A1 (pt)
GB (2) GB9413035D0 (pt)
HU (1) HU219823B (pt)
IE (1) IE950477A1 (pt)
MA (1) MA23595A1 (pt)
NO (1) NO952601L (pt)
NZ (1) NZ272398A (pt)
OA (1) OA10221A (pt)
PL (1) PL309384A1 (pt)
RU (1) RU2112766C1 (pt)
SE (1) SE9502259L (pt)
SK (1) SK83895A3 (pt)
TN (1) TNSN95068A1 (pt)
ZA (1) ZA955288B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11509204A (ja) * 1995-07-13 1999-08-17 ユニバーシテイ・オブ・シンシナテイ 神経線維腫症の治療に有用な化合物
CN1301731A (zh) * 1999-12-24 2001-07-04 上海博德基因开发有限公司 一种新的多肽——多异戊二烯基合成酶蛋白9和编码这种多肽的多核苷酸
WO2002046414A2 (en) * 2000-12-07 2002-06-13 Bristol-Myers Squibb Company Human g-protein coupled receptor expressed highly in kidney
US20030212017A1 (en) * 2002-05-10 2003-11-13 Isis Pharmaceuticals Inc. Antisense modulation of farnesyl transferase beta subunit expression
US7507808B2 (en) * 2002-12-12 2009-03-24 Isis Pharmaceuticals, Inc. Modulation of endothelial lipase expression
BRPI0414222B8 (pt) 2003-09-09 2021-05-25 Geron Corp compostos oligonucleotídeos modificados para inibição da telomerase, métodos, composição farmacêutica e usos relacionados
WO2008094640A2 (en) 2007-01-30 2008-08-07 Geron Corporation Compounds having anti-adhesive effects on cancer cells
JOP20200257A1 (ar) 2014-05-01 2017-06-16 Geron Corp تركيبات أوليجو نوكليوتيد وطرق لتحضيرها

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4571421A (en) * 1979-11-05 1986-02-18 Genentech, Inc. Mammalian gene for microbial expression
US5004803A (en) * 1988-11-14 1991-04-02 Genetics Institute, Inc. Production of procoagulant proteins
US5420245A (en) * 1990-04-18 1995-05-30 Board Of Regents, The University Of Texas Tetrapeptide-based inhibitors of farnesyl transferase
US5185248A (en) * 1990-05-08 1993-02-09 E. R. Squibb & Sons, Inc. Farnesyl-protein transferase assay for identifying compounds that block neoplastic transformation
KR100242671B1 (ko) * 1991-03-07 2000-03-02 고돈 에릭 유전학적으로 처리한 백신 균주
NZ244820A (en) * 1991-10-25 1994-01-26 Isis Pharmaceuticals Inc Oligonucleotide inhibitor of epstein-barr virus.
US5348853A (en) * 1991-12-16 1994-09-20 Biotronics Corporation Method for reducing non-specific priming in DNA amplification
US5585479A (en) * 1992-07-24 1996-12-17 The United States Of America As Represented By The Secretary Of The Navy Antisense oligonucleotides directed against human ELAM-I RNA

Also Published As

Publication number Publication date
FR2721930A1 (fr) 1996-01-05
CZ168895A3 (en) 1996-05-15
GB2290791B (en) 1998-08-05
NO952601D0 (no) 1995-06-28
GB9413035D0 (en) 1994-08-17
CA2152233A1 (en) 1995-12-30
FI953170A (fi) 1995-12-30
HUT72133A (en) 1996-03-28
AU2329995A (en) 1996-01-11
TNSN95068A1 (fr) 1996-02-06
SK83895A3 (en) 1996-05-08
SE9502259D0 (sv) 1995-06-21
PL309384A1 (en) 1996-01-08
AU689887B2 (en) 1998-04-09
FR2721827A1 (fr) 1996-01-05
JPH0851985A (ja) 1996-02-27
KR960000914A (ko) 1996-01-25
FI953170A0 (fi) 1995-06-27
NO952601L (no) 1996-01-02
HU219823B (hu) 2001-08-28
RU2112766C1 (ru) 1998-06-10
CZ291496B6 (cs) 2003-03-12
EP0692535A1 (fr) 1996-01-17
NZ272398A (en) 1996-04-26
OA10221A (fr) 1997-09-19
IE950477A1 (en) 1996-01-10
FR2721930B1 (fr) 1997-01-03
DZ1903A1 (fr) 2002-02-17
CN1124142A (zh) 1996-06-12
HU9501913D0 (en) 1995-08-28
RU95110774A (ru) 1997-04-20
SE9502259L (sv) 1995-12-30
US5856461A (en) 1999-01-05
MA23595A1 (fr) 1995-12-31
GB9513246D0 (en) 1995-09-06
ZA955288B (en) 1996-01-31
GB2290791A (en) 1996-01-10

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law