BR9407154A - Inalador de pó - Google Patents

Inalador de pó

Info

Publication number
BR9407154A
BR9407154A BR9407154A BR9407154A BR9407154A BR 9407154 A BR9407154 A BR 9407154A BR 9407154 A BR9407154 A BR 9407154A BR 9407154 A BR9407154 A BR 9407154A BR 9407154 A BR9407154 A BR 9407154A
Authority
BR
Brazil
Prior art keywords
chamber
air
opening
hole
swirling
Prior art date
Application number
BR9407154A
Other languages
English (en)
Inventor
Ernst Hoerlin
Original Assignee
Ernst Hoerlin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ernst Hoerlin filed Critical Ernst Hoerlin
Publication of BR9407154A publication Critical patent/BR9407154A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00—Characteristics of a physical parameter; associated device therefor
    • A61M2206/10—Flow characteristics
    • A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nozzles (AREA)
  • Cyclones (AREA)
  • Die Bonding (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Resistance Heating (AREA)
  • Separation Of Particles Using Liquids (AREA)
  • Indicating Or Recording The Presence, Absence, Or Direction Of Movement (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
  • Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)
  • Confectionery (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
BR9407154A 1993-07-30 1994-07-25 Inalador de pó BR9407154A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE19939302550A SE9302550D0 (sv) 1993-07-30 1993-07-30 Powder inhaler
PCT/SE1994/000704 WO1995003846A1 (en) 1993-07-30 1994-07-25 Powder inhaler

Publications (1)

Publication Number Publication Date
BR9407154A true BR9407154A (pt) 1996-09-17

Family

ID=20390722

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9407154A BR9407154A (pt) 1993-07-30 1994-07-25 Inalador de pó

Country Status (23)

Country Link
US (1) US6230707B1 (pt)
EP (2) EP1291032B1 (pt)
JP (2) JP3225966B2 (pt)
KR (1) KR100319366B1 (pt)
CN (1) CN1121244C (pt)
AT (2) ATE295195T1 (pt)
AU (1) AU682052B2 (pt)
BR (1) BR9407154A (pt)
CA (1) CA2167509C (pt)
DE (2) DE69434375T2 (pt)
DK (2) DK1291032T3 (pt)
ES (2) ES2187528T3 (pt)
FI (1) FI119222B (pt)
LV (1) LV11435B (pt)
NO (1) NO313618B1 (pt)
NZ (1) NZ269855A (pt)
PL (1) PL176849B1 (pt)
PT (1) PT1291032E (pt)
RU (1) RU2127612C1 (pt)
SE (1) SE9302550D0 (pt)
SG (1) SG49333A1 (pt)
SI (1) SI0714313T1 (pt)
WO (1) WO1995003846A1 (pt)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2735043B1 (fr) * 1995-06-09 1998-09-25 Valois Dispositif pour faciliter le vidage d'une chambre de dosage d'un inhalateur
US6470884B2 (en) 1996-01-29 2002-10-29 Aventis Pharma Limited Capsule opening arrangement for use in a powder inhaler
US6123070A (en) * 1996-06-07 2000-09-26 Valois S.A. Device for enhancing the emptying of an inhaler metering chamber
DE19647947A1 (de) * 1996-11-20 1998-05-28 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
GB9626233D0 (en) * 1996-12-18 1997-02-05 Chawla Brinda P S Medicament packaging and deliveery device
AU771799B2 (en) * 1997-02-07 2004-04-01 Astra Aktiebolag Single dose inhaler II
SE9700422D0 (sv) * 1997-02-07 1997-02-07 Astra Ab Single dose inhaler II
TW469832U (en) * 1997-03-14 2001-12-21 Astra Ab Inhalation device
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
WO1999024057A2 (en) * 1997-11-07 1999-05-20 Genetics Inst Neuronal uses of bmp-11
GB2344533B (en) * 1998-12-11 2000-10-18 Bespak Plc Improvements in or relating to dispensing apparatus
JP2000217917A (ja) 1999-01-27 2000-08-08 Unisia Jecs Corp 吸入式投薬器
SE517806C2 (sv) * 1999-11-11 2002-07-16 Microdrug Ag Doseringsanordning för inhalator
US6427688B1 (en) * 2000-02-01 2002-08-06 Dura Pharmaceuticals, Icn. Dry powder inhaler
US7171965B2 (en) * 2000-02-01 2007-02-06 Valois S.A.S. Breath actuated dry powder inhaler and tape dose strip
AUPQ582100A0 (en) * 2000-02-24 2000-03-16 Irm Technologies Pty Ltd Nasal filter and sampler
WO2001085136A2 (en) * 2000-05-10 2001-11-15 Alliance Pharmaceutical Corporation Phospholipid-based powders for drug delivery
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US20030003057A1 (en) * 2000-07-07 2003-01-02 Jeffry Weers Methods for administering leuprolide by inhalation
GB2364919A (en) * 2000-07-21 2002-02-13 Cambridge Consultants Inhalers
EP1238680B1 (en) * 2001-03-05 2003-12-10 Ivo Pera Inhaling device for dispersing powdered medicaments contained in a capsule through the respiratory tract
WO2003041777A1 (en) * 2001-11-14 2003-05-22 Nektar Therapeutics Aerosolization device with improved endpiece connection
EP1443996B1 (en) * 2001-11-14 2011-05-18 Novartis AG Aerosolization apparatus comprising connectable body and endpiece
AU2002216925B2 (en) * 2001-11-22 2009-06-11 Eckardt, Angela Inhalation device for dry powder controlled by inspiration
GB0130055D0 (en) * 2001-12-14 2002-02-06 Technology Innovation Ltd Medicament packaging
MXPA04005865A (es) * 2001-12-19 2004-09-13 Nektar Therapeutics Suministro de aminoglucosidos a los pulmones.
US8777011B2 (en) * 2001-12-21 2014-07-15 Novartis Ag Capsule package with moisture barrier
EP1472140A1 (en) * 2001-12-21 2004-11-03 Nektar Therapeutics Apparatus and method for sealing cavities
US6941980B2 (en) * 2002-06-27 2005-09-13 Nektar Therapeutics Apparatus and method for filling a receptacle with powder
US20040206350A1 (en) * 2002-12-19 2004-10-21 Nektar Therapeutics Aerosolization apparatus with non-circular aerosolization chamber
EP1603810B1 (en) * 2003-03-15 2010-08-11 Brin Tech International Limited Medicament package
PL1610850T3 (pl) 2003-04-09 2012-11-30 Novartis Ag Urządzenie rozpylające z osłoną wlotu powietrza
PL1615689T3 (pl) * 2003-04-09 2016-06-30 Novartis Ag Urządzenie do aerozolizacji z prowadnicą wyrównującą do przebijania kapsułki
US8869794B1 (en) 2003-04-09 2014-10-28 Novartis Pharma Ag Aerosolization apparatus with capsule puncturing member
EP1627654A1 (en) * 2003-05-28 2006-02-22 Hitachi Ltd. Inhalation type dosing device
US20060231096A1 (en) * 2003-06-11 2006-10-19 Hitachi, Ltd. Inhalation type medication apparatus
CA2562386C (en) 2004-04-21 2014-11-18 Innovata Biomed Limited Inhaler
AU2005303596B2 (en) * 2004-11-10 2011-08-18 Cipla Limited Inhaler
US8763605B2 (en) 2005-07-20 2014-07-01 Manta Devices, Llc Inhalation device
EP2957312B1 (en) * 2005-07-20 2019-12-04 Manta Devices, LLC Inhalation device
WO2007041090A2 (en) * 2005-09-29 2007-04-12 Nektar Therapeutics Receptacles and kits, such as for dry powder packaging
CN101437562A (zh) * 2006-03-03 2009-05-20 Stc.Unm公司 具有气动力弹性分散机构的干粉吸入器
US8127763B2 (en) 2006-03-03 2012-03-06 Stc.Unm Dry powder inhaler with aeroelastic dispersion mechanism
US11224704B2 (en) * 2007-07-06 2022-01-18 Manta Devices, Llc Dose delivery device for inhalation
DK2898914T3 (en) 2007-07-06 2018-09-03 Manta Devices Llc INHALATION DEVICES FOR STORAGE AND DELIVERY OF MEDICINES
KR20100098610A (ko) * 2007-10-25 2010-09-08 노파르티스 아게 단위 투여량의 약물 포장물의 분말 컨디셔닝
EP2534958A1 (en) 2007-12-14 2012-12-19 AeroDesigns, Inc Delivering aerosolizable food products
EP2082764A1 (en) 2008-01-24 2009-07-29 Boehringer Ingelheim International GmbH Inhaler
ES2546025T3 (es) * 2008-01-24 2015-09-17 Vectura Delivery Devices Limited Inhalador
FR2933620B1 (fr) * 2008-07-11 2010-09-03 Valois Sa Dispositif d'inhalation de poudre.
SG172177A1 (en) * 2008-12-15 2011-07-28 Profibrix Bv Powder delivery device
US8550074B2 (en) * 2009-01-15 2013-10-08 Manta Devices, Llc Delivery device and related methods
WO2010131188A1 (en) * 2009-05-11 2010-11-18 Koninklijke Philips Electronics N.V. Aerosol drug delivery apparatus and method
GB0914738D0 (en) * 2009-08-24 2009-09-30 Cambridge Consultants Inhalers
AU2010319328A1 (en) 2009-11-12 2012-05-31 Stc.Unm Dry powder inhaler with flutter dispersion member
WO2011116293A2 (en) 2010-03-19 2011-09-22 Manta Devices, Llc Delivery device and related methods
WO2012078804A1 (en) * 2010-12-07 2012-06-14 Respira Therapeutics, Inc. Dry powder inhaler
GB201021881D0 (en) 2010-12-23 2011-02-02 Profibrix Bv Powder delivery device
KR101236720B1 (ko) * 2011-02-28 2013-02-25 서울대학교산학협력단 파우더 흡입장치
US11103659B2 (en) 2011-07-06 2021-08-31 Manta Devices, Llc Delivery device and related methods
FR2979058B1 (fr) * 2011-08-19 2013-08-30 Valois Sas Dispositif d'inhalation de poudre.
US9603906B2 (en) 2012-02-01 2017-03-28 Protalix Ltd. Inhalable liquid formulations of DNase I
US20180369513A1 (en) * 2012-02-21 2018-12-27 Respira Therapeutics, Inc. Powder dispersion devices and methods
US10463815B2 (en) * 2012-02-21 2019-11-05 Respira Therapeutics, Inc. Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents
JP2015107056A (ja) * 2012-03-16 2015-06-11 日本たばこ産業株式会社 非加熱型香味吸引器
US9649454B2 (en) 2012-05-03 2017-05-16 Manta Devices, Llc Delivery device and related methods
CN103272315B (zh) * 2013-04-28 2019-02-22 河南科技大学第一附属医院 一种上呼吸道的吸药装置
EP3110484A4 (en) 2014-02-21 2018-02-14 Respira Therapeutics, Inc. Powder inhaler, system and methods
US11147936B2 (en) 2014-05-02 2021-10-19 Manta Devices, Llc Dose delivery device with cover connected to dose chamber seal
US20170304459A1 (en) 2014-10-10 2017-10-26 Alnylam Pharmaceuticals, Inc. Methods and compositions for inhalation delivery of conjugated oligonucleotide
MX2017009112A (es) 2015-01-14 2018-06-15 Respira Therapeutics Inc Metodos y dispositivos de dispersion de polvo.
CN107614038B (zh) 2015-04-15 2021-04-20 菲利普莫里斯生产公司 具有部分剂量输送的干粉吸入器
US20170071505A1 (en) * 2015-09-16 2017-03-16 Methocholine Dry Powder Delivery System and Method
US11471622B2 (en) * 2016-11-30 2022-10-18 Philip Morris Products S.A. Inhaler with swirl end plug
EP3630242B1 (en) * 2017-05-31 2021-05-05 Philip Morris Products S.A. Inhaler article with occluded airflow element
US11744967B2 (en) * 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
CN109821118A (zh) * 2017-11-23 2019-05-31 正大天晴药业集团股份有限公司 新型肺部药物输送系统
BR112021021775A2 (pt) 2019-04-29 2022-01-04 Insmed Inc Composições de pó seco de pró-fármacos de treprostinil e métodos de uso destas
DE102019219277A1 (de) * 2019-12-10 2021-06-10 Christian-Albrechts-Universität Zu Kiel Pulverförmige Formulierungen zur Inhalation
WO2023150747A1 (en) 2022-02-07 2023-08-10 Insmed Incorporated Dry powder compositions of bedaquiline and salts and methods of use thereof
WO2024165648A1 (en) * 2023-02-07 2024-08-15 The Materia Company Limited Apparatus for topical delivery of capsule powder

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE483136A (pt) * 1947-09-04 1942-06-30
US2470296A (en) * 1948-04-30 1949-05-17 Abbott Lab Inhalator
US2534636A (en) * 1949-02-12 1950-12-19 American Cyanamid Co Powder dispenser
US4069819A (en) * 1973-04-13 1978-01-24 Societa Farmaceutici S.P.A. Inhalation device
US3980074A (en) * 1973-07-18 1976-09-14 Beecham Group Limited Device for the administration of powders
YU41046B (en) * 1974-08-22 1986-10-31 Schering Ag Medicine inholating device
FR2352556A1 (fr) 1976-05-26 1977-12-23 Pasteur Institut Inhalateur de poudre
AT384552B (de) * 1985-08-01 1987-12-10 Hurka Wilhelm Inhalationsgeraet zur dosierung und verteilung von festkoerpern in die atemluft
GB8804069D0 (en) * 1988-02-22 1988-03-23 Britains Petite Ltd Dispensers for powdered medication
DE407028T1 (de) * 1989-05-31 1994-03-17 Fisons Plc Medikament und Inhalationsvorrichtung dafür.
FI84698C (fi) * 1989-06-16 1992-01-10 Huhtamaeki Oy Anordning foer finfoerdelning av agglomerat av en enkeldos av ett laekemedelpreparat i pulverform.
DE59107894D1 (de) * 1991-03-21 1996-07-11 Ritzau Pari Werk Gmbh Paul Vernebler insbesondere zur Anwendung in Geräten für die Inhalationstherapie
DE4211475A1 (de) * 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
AT398277B (de) * 1992-12-11 1994-11-25 Hurka Wilhelm Inhalationsgerät
IL108780A (en) * 1993-02-27 1999-06-20 Fisons Plc inhaler
HU219117B (hu) * 1994-09-16 2001-02-28 Laboratoire Glaxo Wellcome S.A. Inhalálóeszköz

Also Published As

Publication number Publication date
SG49333A1 (en) 1998-05-18
NO960368D0 (no) 1996-01-29
DK1291032T3 (da) 2005-08-29
CA2167509C (en) 2005-02-01
EP1291032A2 (en) 2003-03-12
JPH09503928A (ja) 1997-04-22
ATE295195T1 (de) 2005-05-15
WO1995003846A1 (en) 1995-02-09
AU7351994A (en) 1995-02-28
DE69434375D1 (de) 2005-06-16
FI960393A0 (fi) 1996-01-29
DK0714313T3 (da) 2003-03-31
EP1291032A3 (en) 2003-05-02
ATE231014T1 (de) 2003-02-15
JP3736837B2 (ja) 2006-01-18
CN1130357A (zh) 1996-09-04
AU682052B2 (en) 1997-09-18
FI119222B (fi) 2008-09-15
ES2187528T3 (es) 2003-06-16
PL312735A1 (en) 1996-05-13
KR100319366B1 (ko) 2002-07-02
RU2127612C1 (ru) 1999-03-20
PT1291032E (pt) 2005-07-29
EP0714313A1 (en) 1996-06-05
NO313618B1 (no) 2002-11-04
NZ269855A (en) 1997-12-19
SI0714313T1 (en) 2003-04-30
NO960368L (no) 1996-03-20
JP2001187143A (ja) 2001-07-10
DE69434375T2 (de) 2005-11-24
JP3225966B2 (ja) 2001-11-05
ES2238536T3 (es) 2005-09-01
FI960393A (fi) 1996-01-29
SE9302550D0 (sv) 1993-07-30
DE69432021T2 (de) 2003-09-25
CA2167509A1 (en) 1995-02-09
PL176849B1 (pl) 1999-08-31
CN1121244C (zh) 2003-09-17
LV11435B (en) 1996-12-20
EP1291032B1 (en) 2005-05-11
LV11435A (lv) 1996-08-20
US6230707B1 (en) 2001-05-15
EP0714313B1 (en) 2003-01-15
DE69432021D1 (de) 2003-02-20

Similar Documents

Publication Publication Date Title
BR9407154A (pt) Inalador de pó
DE59202210D1 (de) Spritze für medizinische Zwecke.
FI892410A0 (fi) Ny avsatt absorberande kiseldioxid och dess baskomposition.
DE69934508D1 (de) Infrarotthermomether
DE59105399D1 (de) Flüssigkeitszerstäubervorrichtung.
DE3852885D1 (de) Parenterale anordnung.
TW566498U (en) Telescopic unit
FI930051A0 (fi) 4,13-dioxabicyklo(8.2.1)tridecenonderivat sam foerfarande och mellanprodukt foer deras framstaellning
DE59703987D1 (de) Lautsprecher
FI924857A0 (fi) Veterinaerinstrument foer givande av en laekemedelkomposition
ES285607Y (es) Boquilla de acoplamiento para instalaciones de aspiracion centralizadas
GB0030984D0 (en) Sampling device
ATE224789T1 (de) Ausblaseinrichtung für eine mehrfachkupplung
ES2121771T3 (es) Formulacion granular dispersable de propanil.
DE69209463D1 (de) Hochspannungsschalter
FI910009A (fi) Stroem-spaenningsomvandlare foer elektroniska hushaollselmaetare.
DE50008950D1 (de) Expansionskühldüse
JPS5773228A (en) Bar field uniform joint
ATE237983T1 (de) Vorrichtung mit einem fliegenschwamm
FI893892A (fi) Luftfoerdelningsanordning.
SE8200138L (sv) Kanyl/kateteraggregat samt kanyl och kateter for astadkommande av det
AU1524792A (en) Veress needle assembly
FI931649A (fi) Kärkiosapipetti

Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
B25A Requested transfer of rights approved

Free format text: AVENTIS PHARMA LIMITED (GB)

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B24H Lapse because of non-payment of annual fees (definitively: art 78 iv lpi)
B24F Patent annual fee: publication cancelled

Free format text: ANULADA A PUBLICACAO CODIGO 24.8 NA RPI NO 2277 DE 26/08/2014 POR TER SIDO INDEVIDA.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE AS 19A, 20A E 21A ANUIDADES.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2607 DE 22-12-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.