BR9400600A - Processos para produção de uma protéina recombinante e/ou de glicosilfosfatidilinositol (GPI) em células de microorganismos eucariontes e para a obtenção de leveduras de S. cerevisae; célula de levedura sequência de nucleotídios; meio de cultura; medicamento ou vacina; e produto dos ditos processos - Google Patents

Processos para produção de uma protéina recombinante e/ou de glicosilfosfatidilinositol (GPI) em células de microorganismos eucariontes e para a obtenção de leveduras de S. cerevisae; célula de levedura sequência de nucleotídios; meio de cultura; medicamento ou vacina; e produto dos ditos processos

Info

Publication number
BR9400600A
BR9400600A BR9400600A BR9400600A BR9400600A BR 9400600 A BR9400600 A BR 9400600A BR 9400600 A BR9400600 A BR 9400600A BR 9400600 A BR9400600 A BR 9400600A BR 9400600 A BR9400600 A BR 9400600A
Authority
BR
Brazil
Prior art keywords
processes
cerevisae
glycosylphosphatidylinositol
gpi
yeasts
Prior art date
Application number
BR9400600A
Other languages
English (en)
Portuguese (pt)
Inventor
De Almeida Maria Lucia Cardoso
De Castilho Valavicius Amaral
De Amorim Antonio Filho Gomes
Original Assignee
Finep Financiadora De Estudos
Escola Paulista De Medicina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Finep Financiadora De Estudos, Escola Paulista De Medicina filed Critical Finep Financiadora De Estudos
Priority to BR9400600A priority Critical patent/BR9400600A/pt
Priority to PCT/BR1995/000010 priority patent/WO1995022614A1/fr
Publication of BR9400600A publication Critical patent/BR9400600A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6481—Phosphoglycerides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/90—Fusion polypeptide containing a motif for post-translational modification
    • C07K2319/91—Fusion polypeptide containing a motif for post-translational modification containing a motif for glycosylation
    • C07K2319/912—Fusion polypeptide containing a motif for post-translational modification containing a motif for glycosylation containing a GPI (phosphatidyl-inositol glycane) anchor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BR9400600A 1994-02-17 1994-02-17 Processos para produção de uma protéina recombinante e/ou de glicosilfosfatidilinositol (GPI) em células de microorganismos eucariontes e para a obtenção de leveduras de S. cerevisae; célula de levedura sequência de nucleotídios; meio de cultura; medicamento ou vacina; e produto dos ditos processos BR9400600A (pt)

Priority Applications (2)

Application Number Priority Date Filing Date Title
BR9400600A BR9400600A (pt) 1994-02-17 1994-02-17 Processos para produção de uma protéina recombinante e/ou de glicosilfosfatidilinositol (GPI) em células de microorganismos eucariontes e para a obtenção de leveduras de S. cerevisae; célula de levedura sequência de nucleotídios; meio de cultura; medicamento ou vacina; e produto dos ditos processos
PCT/BR1995/000010 WO1995022614A1 (fr) 1994-02-17 1995-02-16 Production de proteines recombinees ancrees par glycosylphosphatidylinositol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BR9400600A BR9400600A (pt) 1994-02-17 1994-02-17 Processos para produção de uma protéina recombinante e/ou de glicosilfosfatidilinositol (GPI) em células de microorganismos eucariontes e para a obtenção de leveduras de S. cerevisae; célula de levedura sequência de nucleotídios; meio de cultura; medicamento ou vacina; e produto dos ditos processos

Publications (1)

Publication Number Publication Date
BR9400600A true BR9400600A (pt) 1995-10-24

Family

ID=4058332

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9400600A BR9400600A (pt) 1994-02-17 1994-02-17 Processos para produção de uma protéina recombinante e/ou de glicosilfosfatidilinositol (GPI) em células de microorganismos eucariontes e para a obtenção de leveduras de S. cerevisae; célula de levedura sequência de nucleotídios; meio de cultura; medicamento ou vacina; e produto dos ditos processos

Country Status (2)

Country Link
BR (1) BR9400600A (fr)
WO (1) WO1995022614A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP940432B1 (en) * 1994-08-05 2003-10-31 Pliva Pharm & Chem Works Dna sequences encoding biosynthetic insulin precursors and process for preparation of insulin
US6113917A (en) * 1995-04-25 2000-09-05 Rmf Dictagene S.A. Modified polypeptides for enhanced immunogenicity
US7312062B2 (en) 1998-11-27 2007-12-25 Novozymes A/S Lipolytic enzyme variants
ATE328605T1 (de) 2000-03-24 2006-06-15 Genentech Inc Verwendung von insulin zur behandlung von knorpelkrankheiten
ATE365224T1 (de) * 2002-11-22 2007-07-15 Eisai R&D Man Co Ltd Verfahren zum screening nach verbindungen, die die enzymatische aktivität des gwt1 genproduktes hemmen
ATE479760T1 (de) * 2004-03-24 2010-09-15 Domantis Ltd Universelles signalpeptid gas1
WO2007128766A1 (fr) * 2006-05-10 2007-11-15 Novozymes A/S Procedes d'extraction de composants d'une culture de cellules de levure
WO2008100816A2 (fr) * 2007-02-09 2008-08-21 Medimmune, Llc Présentation d'anticorps

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA808097B (en) * 1980-12-29 1982-01-27 Lilly Co Eli Novel insulin formulations
US5109113A (en) * 1986-05-02 1992-04-28 Genentech, Inc. Membrane anchor fusion polypeptides
WO1989005825A1 (fr) * 1987-12-22 1989-06-29 Immunex Corporation EXPRESSION D'ANTIGENES DE PROTEINES 18/16,6 et 15,2 kD RECOMBINANTES DE MYCOBACTERIUM LEPRAE
US5223394A (en) * 1989-04-10 1993-06-29 Biogen, Inc. Recombinant dna molecule comprising lymphocyte function-associated antigen 3 phosphatidylinositol linkage signal sequence
WO1992001715A1 (fr) * 1990-07-19 1992-02-06 The Board Of Trustees Of The Leland Stanford Junior University Proteines dimeres solubles de surface cellulaire
EP0477739A3 (en) * 1990-09-27 1992-12-09 F. Hoffmann-La Roche Ag Glycosyl-phosphatidylinositol-specific phospholipase d
US5573779A (en) * 1992-04-10 1996-11-12 Hisamitsu Pharmaceutical Co., Inc. Liposome composition
EP1018343A1 (fr) * 1992-07-10 2000-07-12 University Of British Columbia Utilisation de p97 et des protéines liant le fer comme agents diagnostiques et thérapeutiques

Also Published As

Publication number Publication date
WO1995022614A1 (fr) 1995-08-24

Similar Documents

Publication Publication Date Title
ATE290589T1 (de) Rekombinante hefe zur effizienten fermentation von glucose und xylose
BR9507678A (pt) Construção de dna vetor de expressão recombinante célula proceso para produzir uma enzima enzima preparação de enzima uso da enzima e cultura
EP0945515A3 (fr) Production de protéines par recombinaison homologue
BR8200191A (pt) Celula viva renina preprorrenina prorrenina processo para obter expressao de preporrenina prorrenina e renina gene de prorrenina preprorrenina e renina e coli material dna recombinador saccharomyces cerevisiae polipetidio processo para exprimir um gene
BR8106137A (pt) Polipeptidio sequencia de dna veiculo de expressao microbiiana copiavel plasmidio microorganismo composicao extrato bacteriano composicao farmaceutica cultura de celulas microbianas aplicacao de um interferon e processos de producaode alguns desses itens
ES2255281T3 (es) Sobreexpresion de genes de fitasa en sistmas de levadura.
FI885679A (fi) Samuttryckning i eukariotiska celler.
IE840258L (en) Expression of gene products.
BR9400600A (pt) Processos para produção de uma protéina recombinante e/ou de glicosilfosfatidilinositol (GPI) em células de microorganismos eucariontes e para a obtenção de leveduras de S. cerevisae; célula de levedura sequência de nucleotídios; meio de cultura; medicamento ou vacina; e produto dos ditos processos
WO1999025878A3 (fr) Procedes pour moduler et identifier la senescence cellulaire
AU621810B2 (en) Amylolytic enzymes producing microorganisms, constructed by recombinant DNA technology and their use for fermentation processes
GB1170929A (en) Antirival Nucleic Acids.
AU551487B2 (en) Culturing human cells in algae extract
CA2031286A1 (fr) Methodes d'inactivation biologique des acides nucleiques
CA2390104A1 (fr) Procede de transfert de substances moleculaires au moyen de proteines procaryotiques liant des acides nucleiques
AU586874B2 (en) Invasive microorganisms
WO2000006713A3 (fr) Techniques et produits de recombinaison relatifs a une expression de proteine
AU7137996A (en) Materials and methods relating to the transfer of nucleic acid into quiescent cells
AU6464699A (en) Labeling, immobilisation, enrichment, purification and detection of cells using specific domains that bind to the cell walls (cbd) of proteins binding to the drawn cell walls of viruses, bacteria or eukaryotic cells
AU6113098A (en) Compositions for treatment of disorders involving programmed cell death
WO2001079525A3 (fr) Acides nucleiques et poypeptides purifies et isoles cotransporteurs de chlorure de potassium
AU1948788A (en) Expression of immunologically active proteins of human b-lymphotropic virus
PT801682E (pt) Processo para a producao de proteinas
FR2603040B1 (fr) Proteine, sequence d'adn, poxvirus, cellules et leur procede de culture, ainsi que les compositions pharmaceutiques les contenant, utiles dans la prevention de la schistosomose
WO2000037682A8 (fr) Procede permettant d'accroitre l'expression d'un gene etranger

Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B15K Others concerning applications: alteration of classification

Ipc: C12P 7/64 (2006.01), C07K 14/35 (2006.0