BR112023024279A2 - Processo de fermentação em lote alimentado - Google Patents

Processo de fermentação em lote alimentado

Info

Publication number
BR112023024279A2
BR112023024279A2 BR112023024279A BR112023024279A BR112023024279A2 BR 112023024279 A2 BR112023024279 A2 BR 112023024279A2 BR 112023024279 A BR112023024279 A BR 112023024279A BR 112023024279 A BR112023024279 A BR 112023024279A BR 112023024279 A2 BR112023024279 A2 BR 112023024279A2
Authority
BR
Brazil
Prior art keywords
fed
fermentation broth
fermentation process
batch fermentation
fed batch
Prior art date
Application number
BR112023024279A
Other languages
English (en)
Inventor
Adrianus Van Winden Wouter
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of BR112023024279A2 publication Critical patent/BR112023024279A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/58—Reaction vessels connected in series or in parallel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
    • G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
    • G16C20/10—Analysis or design of chemical reactions, syntheses or processes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • Computer Hardware Design (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

processo de fermentação em lote alimentado. a presente invenção se refere a um método para cultivo de um microrganismo, compreendendo as etapas de: (i) adicionar a um primeiro biorreator um meio e um inóculo compreendendo o microrganismo e produzir um caldo de fermentação em cultura em lote alimentado; e (ii) adicionar a um segundo biorreator um segundo meio e parte do caldo de fermentação da etapa (i) e produzir um segundo caldo de fermentação em uma segunda cultura em lote alimentado; e (iii) adicionar a um próximo biorreator um próximo meio e uma parte do caldo de fermentação da etapa (ii), e produzir um próximo caldo de fermentação em uma próxima cultura em lote alimentado; em que uma alimentação é introduzida aos primeiro, segundo e próximo biorreatores.
BR112023024279A 2021-05-25 2022-05-24 Processo de fermentação em lote alimentado BR112023024279A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP21175746 2021-05-25
PCT/EP2022/064059 WO2022248476A1 (en) 2021-05-25 2022-05-24 Fed-batch fermentation process

Publications (1)

Publication Number Publication Date
BR112023024279A2 true BR112023024279A2 (pt) 2024-01-30

Family

ID=76098879

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112023024279A BR112023024279A2 (pt) 2021-05-25 2022-05-24 Processo de fermentação em lote alimentado

Country Status (5)

Country Link
US (1) US20240271074A1 (pt)
EP (1) EP4347852A1 (pt)
CN (1) CN117355611A (pt)
BR (1) BR112023024279A2 (pt)
WO (1) WO2022248476A1 (pt)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1918382A1 (en) * 2006-11-02 2008-05-07 DSMIP Assets B.V. Semi-continuous cascade fermentation process for pantothenate production
KR100834110B1 (ko) * 2007-01-25 2008-06-02 한국과학기술원 상류 충전탑 세포재순환 장치가 장착된 다단계 ｃｓｔｒ생물반응기 시스템
EP2403954B1 (en) * 2009-03-03 2015-04-22 POET Research, Inc. Method for fermentation of biomass for the production of ethanol
FI126781B (en) 2015-05-25 2017-05-31 Neste Corp Methods for the continuous production of products from microorganisms

Also Published As

Publication number Publication date
CN117355611A (zh) 2024-01-05
WO2022248476A1 (en) 2022-12-01
EP4347852A1 (en) 2024-04-10
US20240271074A1 (en) 2024-08-15

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