BR112023023890A2 - Ligantes radiofarmacêuticos de receptor de somatostatina e precursores dos mesmos - Google Patents
Ligantes radiofarmacêuticos de receptor de somatostatina e precursores dos mesmosInfo
- Publication number
- BR112023023890A2 BR112023023890A2 BR112023023890A BR112023023890A BR112023023890A2 BR 112023023890 A2 BR112023023890 A2 BR 112023023890A2 BR 112023023890 A BR112023023890 A BR 112023023890A BR 112023023890 A BR112023023890 A BR 112023023890A BR 112023023890 A2 BR112023023890 A2 BR 112023023890A2
- Authority
- BR
- Brazil
- Prior art keywords
- precursors
- radiopharmaceutical
- sst
- somatostatin receptor
- linders
- Prior art date
Links
- 108050001286 Somatostatin Receptor Proteins 0.000 title abstract 2
- 102000011096 Somatostatin receptor Human genes 0.000 title abstract 2
- 239000002243 precursor Substances 0.000 title abstract 2
- 239000012217 radiopharmaceutical Substances 0.000 title abstract 2
- 229940121896 radiopharmaceutical Drugs 0.000 title abstract 2
- 230000002799 radiopharmaceutical effect Effects 0.000 title abstract 2
- 239000003446 ligand Substances 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000002285 radioactive effect Effects 0.000 abstract 2
- 102000005962 receptors Human genes 0.000 abstract 2
- 108020003175 receptors Proteins 0.000 abstract 2
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 239000013522 chelant Substances 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 230000000155 isotopic effect Effects 0.000 abstract 1
- 201000011519 neuroendocrine tumor Diseases 0.000 abstract 1
- ABTOQLMXBSRXSM-UHFFFAOYSA-N silicon tetrafluoride Chemical compound F[Si](F)(F)F ABTOQLMXBSRXSM-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/12—Organo silicon halides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/0472—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/008—Peptides; Proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/003—Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Optics & Photonics (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21173849 | 2021-05-14 | ||
| PCT/EP2022/062985 WO2022238553A1 (en) | 2021-05-14 | 2022-05-12 | Radiopharmaceutical somatostatin receptor ligands and precursors thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112023023890A2 true BR112023023890A2 (pt) | 2024-01-30 |
Family
ID=75936725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112023023890A BR112023023890A2 (pt) | 2021-05-14 | 2022-05-12 | Ligantes radiofarmacêuticos de receptor de somatostatina e precursores dos mesmos |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20240317780A1 (https=) |
| EP (1) | EP4337270A1 (https=) |
| JP (1) | JP2024517971A (https=) |
| KR (1) | KR20240008341A (https=) |
| CN (1) | CN117320759A (https=) |
| AU (1) | AU2022273184A1 (https=) |
| BR (1) | BR112023023890A2 (https=) |
| CA (1) | CA3214915A1 (https=) |
| IL (1) | IL308414A (https=) |
| MX (1) | MX2023013485A (https=) |
| WO (1) | WO2022238553A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117777296B (zh) * | 2024-02-28 | 2024-05-28 | 北京肿瘤医院(北京大学肿瘤医院) | B7h3亲和体及其诊疗核素标记物的制备方法与应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE070098T2 (hu) * | 2017-07-28 | 2025-05-28 | Univ Muenchen Tech | Kettõs módusú radioaktív jelzõ és terapeutikumok |
-
2022
- 2022-05-12 MX MX2023013485A patent/MX2023013485A/es unknown
- 2022-05-12 CA CA3214915A patent/CA3214915A1/en active Pending
- 2022-05-12 JP JP2023570394A patent/JP2024517971A/ja active Pending
- 2022-05-12 CN CN202280035052.5A patent/CN117320759A/zh active Pending
- 2022-05-12 KR KR1020237042809A patent/KR20240008341A/ko active Pending
- 2022-05-12 IL IL308414A patent/IL308414A/en unknown
- 2022-05-12 EP EP22729145.7A patent/EP4337270A1/en active Pending
- 2022-05-12 AU AU2022273184A patent/AU2022273184A1/en active Pending
- 2022-05-12 US US18/290,061 patent/US20240317780A1/en active Pending
- 2022-05-12 BR BR112023023890A patent/BR112023023890A2/pt unknown
- 2022-05-12 WO PCT/EP2022/062985 patent/WO2022238553A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| IL308414A (en) | 2024-01-01 |
| WO2022238553A1 (en) | 2022-11-17 |
| US20240317780A1 (en) | 2024-09-26 |
| KR20240008341A (ko) | 2024-01-18 |
| AU2022273184A1 (en) | 2023-10-12 |
| MX2023013485A (es) | 2023-12-07 |
| CA3214915A1 (en) | 2022-11-17 |
| EP4337270A1 (en) | 2024-03-20 |
| JP2024517971A (ja) | 2024-04-23 |
| CN117320759A (zh) | 2023-12-29 |
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