BR112023023391A2 - Inibidor de diminuição de esteroide de receptor de interferon tipo 1 em pacientes com lúpus eritematoso sistêmico - Google Patents
Inibidor de diminuição de esteroide de receptor de interferon tipo 1 em pacientes com lúpus eritematoso sistêmicoInfo
- Publication number
- BR112023023391A2 BR112023023391A2 BR112023023391A BR112023023391A BR112023023391A2 BR 112023023391 A2 BR112023023391 A2 BR 112023023391A2 BR 112023023391 A BR112023023391 A BR 112023023391A BR 112023023391 A BR112023023391 A BR 112023023391A BR 112023023391 A2 BR112023023391 A2 BR 112023023391A2
- Authority
- BR
- Brazil
- Prior art keywords
- lupus erythematosus
- systemic lupus
- patients
- steroid
- receptor type
- Prior art date
Links
- 201000000596 systemic lupus erythematosus Diseases 0.000 title abstract 4
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 102000001617 Interferon Receptors Human genes 0.000 title 1
- 108010054267 Interferon Receptors Proteins 0.000 title 1
- 150000003431 steroids Chemical class 0.000 title 1
- 102000014150 Interferons Human genes 0.000 abstract 1
- 108010050904 Interferons Proteins 0.000 abstract 1
- 229940079322 interferon Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Abstract
nibidor de diminuição de esteroide de receptor de interferon tipo 1 em pacientes com lúpus eritematoso sistêmico. a presente invenção refere-se a métodos e composições para o tratamento de lúpus eritematoso sistêmico (sle).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202163187485P | 2021-05-12 | 2021-05-12 | |
US202163230113P | 2021-08-06 | 2021-08-06 | |
PCT/EP2022/062770 WO2022238479A1 (en) | 2021-05-12 | 2022-05-11 | Inhibitor of type 1 interferon receptor steroid sparing in systemic lupus erythematosus patients |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112023023391A2 true BR112023023391A2 (pt) | 2024-01-23 |
Family
ID=82019468
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112023023391A BR112023023391A2 (pt) | 2021-05-12 | 2022-05-11 | Inibidor de diminuição de esteroide de receptor de interferon tipo 1 em pacientes com lúpus eritematoso sistêmico |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP4337696A1 (pt) |
JP (1) | JP2024516886A (pt) |
KR (1) | KR20240006549A (pt) |
AU (1) | AU2022274306A1 (pt) |
BR (1) | BR112023023391A2 (pt) |
CA (1) | CA3219401A1 (pt) |
IL (1) | IL308128A (pt) |
TW (1) | TW202313103A (pt) |
WO (1) | WO2022238479A1 (pt) |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2662390T3 (da) | 2004-06-21 | 2017-11-06 | Squibb & Sons Llc | Interferon alpha receptor 1-antistoffer og anvendelse heraf |
JP5608100B2 (ja) | 2008-02-08 | 2014-10-15 | メディミューン,エルエルシー | 低下したFcリガンド親和性を有する抗IFNAR1抗体 |
PT2473636T (pt) | 2009-09-03 | 2017-02-06 | Medimmune Llc | Diagnóstico de interferão de tipo-1 |
ES2818229T3 (es) * | 2015-08-19 | 2021-04-09 | Astrazeneca Ab | Formulación anti-IFNAR1 estable |
CN106243226B (zh) | 2016-08-05 | 2019-02-12 | 北京智仁美博生物科技有限公司 | 抗人ifnar1的抗体及其用途 |
CN113278070B (zh) | 2021-04-25 | 2022-06-14 | 福州迈新生物技术开发有限公司 | 抗ck17蛋白单克隆抗体及其细胞株、制备方法和应用 |
-
2022
- 2022-05-11 BR BR112023023391A patent/BR112023023391A2/pt unknown
- 2022-05-11 KR KR1020237038761A patent/KR20240006549A/ko unknown
- 2022-05-11 EP EP22729455.0A patent/EP4337696A1/en active Pending
- 2022-05-11 JP JP2023568736A patent/JP2024516886A/ja active Pending
- 2022-05-11 AU AU2022274306A patent/AU2022274306A1/en active Pending
- 2022-05-11 WO PCT/EP2022/062770 patent/WO2022238479A1/en active Application Filing
- 2022-05-11 CA CA3219401A patent/CA3219401A1/en active Pending
- 2022-05-11 IL IL308128A patent/IL308128A/en unknown
- 2022-05-12 TW TW111117746A patent/TW202313103A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
KR20240006549A (ko) | 2024-01-15 |
TW202313103A (zh) | 2023-04-01 |
CA3219401A1 (en) | 2022-11-17 |
AU2022274306A1 (en) | 2023-11-23 |
EP4337696A1 (en) | 2024-03-20 |
JP2024516886A (ja) | 2024-04-17 |
AU2022274306A9 (en) | 2023-11-30 |
IL308128A (en) | 2023-12-01 |
WO2022238479A1 (en) | 2022-11-17 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112015027288A8 (pt) | uso de uma dose de imunossupressor, composição de nanocarreadores sintéticos tolerogênicos e kit | |
BR112015029987A2 (pt) | beta-caseína a2 e a prevenção de inflamação do intestino | |
BR112017011644A2 (pt) | métodos e composições de ativação da ligase parkina | |
BR112015027757A2 (pt) | elastômeros parcialmente fluorados e métodos para a produção e uso dos mesmos | |
BR112015025321A2 (pt) | dispositivo suplementar para um dispositivo de injeção operável manualmente | |
BR112014009528A8 (pt) | métodos e composições para tratar eritropoiese ineficaz | |
BR112022007677A2 (pt) | L-asparaginase recombinante | |
BR112017009440A2 (pt) | uso de composições que modulam a estrutura de cromatina quanto à doença do enxerto versus hospedeiro (gvhd) | |
BR112016024022A2 (pt) | composição de silicone curável | |
BR112022011902A2 (pt) | Terapias de combinação | |
BR112017024180A8 (pt) | Aparelho de alimentação de prendedores | |
BR112017027246A2 (pt) | marcador de indução de degradação de proteína e uso do mesmo | |
BR112014000542A2 (pt) | composições de peroxidase eosinofílica e métodos de uso das mesmas | |
BR112019000989A2 (pt) | método para tratar sulfeto de hidrogênio em uma corrente, sequestrante, composição, e, uso de uma composição | |
CY1115775T1 (el) | Συνθεση ψυκτικου μεσου | |
BR112018067851A2 (pt) | composições e métodos para o tratamento de artrite reumatoide | |
CO2021002637A2 (es) | Arni variante frente a alfa-sinucleína | |
CO2022000270A2 (es) | Inhibidores de enzimas | |
BRPI0512642A (pt) | aparelho e método de proteção contra corrosão | |
BR112023023391A2 (pt) | Inibidor de diminuição de esteroide de receptor de interferon tipo 1 em pacientes com lúpus eritematoso sistêmico | |
BR112013005887A2 (pt) | compostos de sacarídeo substituído e composições dentais | |
BR112015032339A8 (pt) | Composição resistente à água | |
BR112017011375A2 (pt) | fio de aço de alta resistência à tensão | |
BR112017012994A2 (pt) | chapa de aço elétrica | |
BR112019000635A2 (pt) | inibidor de receptor 2 do tipo toll (tlr2) e seu uso, anticorpo, composição e método para tratar uma afecção inflamatória |