BR112022024090A2 - Processo para preparar compostos de amidoxima de fórmula i - Google Patents

Processo para preparar compostos de amidoxima de fórmula i

Info

Publication number
BR112022024090A2
BR112022024090A2 BR112022024090A BR112022024090A BR112022024090A2 BR 112022024090 A2 BR112022024090 A2 BR 112022024090A2 BR 112022024090 A BR112022024090 A BR 112022024090A BR 112022024090 A BR112022024090 A BR 112022024090A BR 112022024090 A2 BR112022024090 A2 BR 112022024090A2
Authority
BR
Brazil
Prior art keywords
formula
amidoxime compounds
substituted
give
preparing amidoxime
Prior art date
Application number
BR112022024090A
Other languages
English (en)
Inventor
Vogt Florian
Borate Kailaskumar
Wolf Bernd
Gebhardt Joachim
Michel Jacques Garivet Guillaume
Shinde Harish
Goetz Roland
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of BR112022024090A2 publication Critical patent/BR112022024090A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/30—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same unsaturated acyclic carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/57—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and carboxyl groups, other than cyano groups, bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
    • C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/002—Nitriles (-CN)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCESSO PARA PREPARAR COMPOSTOS DE AMIDOXIMA DE FÓRMULA I. A presente invenção refere-se a um processo para a preparação de ácidos 4-(N?-hidroxi-carbamimidoil)benzoicos substituídos, que podem ser obtidos por hidratação catalisada por nitrilase de tereftalonitrilas substituídos de fórmula II em um meio aquoso para dar ácidos (amônio) 4-cianobenzoicos IIa. A hidratação é seguida por tratamento do meio de reação aquoso com hidroxilamina ou um sal do mesmo para dar amidoximas I.
BR112022024090A 2020-05-29 2021-05-20 Processo para preparar compostos de amidoxima de fórmula i BR112022024090A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN202021022648 2020-05-29
EP20185642 2020-07-14
PCT/EP2021/063439 WO2021239568A1 (en) 2020-05-29 2021-05-20 Preparation of substituted 4-(n'-hydroxycarbamimidoyl)benzoic acids

Publications (1)

Publication Number Publication Date
BR112022024090A2 true BR112022024090A2 (pt) 2022-12-20

Family

ID=76098951

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022024090A BR112022024090A2 (pt) 2020-05-29 2021-05-20 Processo para preparar compostos de amidoxima de fórmula i

Country Status (8)

Country Link
US (1) US20230183171A1 (pt)
EP (1) EP4157824A1 (pt)
KR (1) KR20230018372A (pt)
CN (1) CN115427401A (pt)
BR (1) BR112022024090A2 (pt)
IL (1) IL298517A (pt)
MX (1) MX2022014913A (pt)
WO (1) WO2021239568A1 (pt)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2729454B1 (en) * 2011-07-08 2015-09-16 Novartis AG Novel trifluoromethyl-oxadiazole derivatives and their use in the treatment of disease
BR122021017881B1 (pt) 2014-06-06 2021-11-23 Basf Se Uso dos compostos, composição agroquímica e método para o combate dos fungos fitopatogênicos
JP6596090B2 (ja) * 2014-12-17 2019-10-23 キングス カレッジ ロンドン レチノイン酸受容体ベータ（ＲＡＲβ）アゴニストとしてのビシクロヘテロアリール−ヘテロアリール−安息香酸化合物
CA3027013A1 (en) 2016-06-09 2017-12-14 Basf Se Substituted oxadiazoles for combating phytopathogenic fungi
BR112018074569B1 (pt) 2016-06-09 2022-10-04 Basf Se Compostos, uso de n-(2,4-difluorofenil)-4-[5-(trifluorometil)-1,2,4-oxadiazol-3-il] benzamida, composição agroquímica e método para combater fungos nocivos fitopatogênicos
BR112020001211B1 (pt) 2017-07-28 2023-05-16 Basf Se Processo para preparar compostos de fórmula i
CN107641622B (zh) * 2017-11-01 2021-10-08 中国科学院天津工业生物技术研究所 可水解对苯二甲腈制备对氰基苯甲酸的腈水解酶
CN113614242A (zh) * 2019-01-22 2021-11-05 巴斯夫欧洲公司 4-氰基苯甲酸或其盐的生产方法

Also Published As

Publication number Publication date
US20230183171A1 (en) 2023-06-15
KR20230018372A (ko) 2023-02-07
EP4157824A1 (en) 2023-04-05
MX2022014913A (es) 2023-01-04
IL298517A (en) 2023-01-01
WO2021239568A1 (en) 2021-12-02
CN115427401A (zh) 2022-12-02

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