BR112022021380A2 - Nanopartículas de rna mensageiro para tratamento - Google Patents

Nanopartículas de rna mensageiro para tratamento

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Publication number
BR112022021380A2
BR112022021380A2 BR112022021380A BR112022021380A BR112022021380A2 BR 112022021380 A2 BR112022021380 A2 BR 112022021380A2 BR 112022021380 A BR112022021380 A BR 112022021380A BR 112022021380 A BR112022021380 A BR 112022021380A BR 112022021380 A2 BR112022021380 A2 BR 112022021380A2
Authority
BR
Brazil
Prior art keywords
treatment
messenger rna
messenger
nanoparticles
rna nanoparticles
Prior art date
Application number
BR112022021380A
Other languages
English (en)
Inventor
Deutsch Samuel
Fay Nicole
Frimannsson Daniel
Haabeth Ole
Mckinlay Colin
Original Assignee
Nutcracker Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nutcracker Therapeutics Inc filed Critical Nutcracker Therapeutics Inc
Publication of BR112022021380A2 publication Critical patent/BR112022021380A2/pt

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
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Abstract

NANOPARTÍCULAS DE RNA MENSAGEIRO PARA TRATAMENTO. O presente documento fornece exemplos de nanopartículas de tratamento de RNA mensageiro e métodos de uso dos mesmos para tratar um paciente. Uma nanopartícula de tratamento de RNA mensageiro pode incluir um ou mais RNAs mensageiros codificando um antígeno específico de tumor e um agente imunomodulador; e uma molécula de veículo de liberação encapsulando os referidos um ou mais RNAs mensageiros.
BR112022021380A 2020-04-22 2021-04-21 Nanopartículas de rna mensageiro para tratamento BR112022021380A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063014074P 2020-04-22 2020-04-22
PCT/US2021/028312 WO2021216647A1 (en) 2020-04-22 2021-04-21 Mrna treatment nanoparticles

Publications (1)

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BR112022021380A2 true BR112022021380A2 (pt) 2022-12-06

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BR112022021380A BR112022021380A2 (pt) 2020-04-22 2021-04-21 Nanopartículas de rna mensageiro para tratamento

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US (1) US11879126B2 (pt)
EP (1) EP4139044A1 (pt)
JP (1) JP2023523150A (pt)
KR (1) KR20230005241A (pt)
CN (1) CN115956003A (pt)
AU (1) AU2021259571A1 (pt)
BR (1) BR112022021380A2 (pt)
CA (1) CA3174267A1 (pt)
IL (1) IL297161A (pt)
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