BR112022020521A2 - Compostos de corante ftalocianina, conjugados e métodos de uso dos mesmos - Google Patents
Compostos de corante ftalocianina, conjugados e métodos de uso dos mesmosInfo
- Publication number
- BR112022020521A2 BR112022020521A2 BR112022020521A BR112022020521A BR112022020521A2 BR 112022020521 A2 BR112022020521 A2 BR 112022020521A2 BR 112022020521 A BR112022020521 A BR 112022020521A BR 112022020521 A BR112022020521 A BR 112022020521A BR 112022020521 A2 BR112022020521 A2 BR 112022020521A2
- Authority
- BR
- Brazil
- Prior art keywords
- conjugates
- phthalocianine
- methods
- color compounds
- disclosed
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B47/00—Porphines; Azaporphines
- C09B47/04—Phthalocyanines abbreviation: Pc
- C09B47/30—Metal-free phthalocyanines
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B47/00—Porphines; Azaporphines
- C09B47/04—Phthalocyanines abbreviation: Pc
- C09B47/08—Preparation from other phthalocyanine compounds, e.g. cobaltphthalocyanineamine complex
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/548—Phosphates or phosphonates, e.g. bone-seeking
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0036—Porphyrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B47/00—Porphines; Azaporphines
- C09B47/04—Phthalocyanines abbreviation: Pc
- C09B47/32—Cationic phthalocyanine dyes
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B69/00—Dyes not provided for by a single group of this subclass
- C09B69/008—Dyes containing a substituent, which contains a silicium atom
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E10/00—Energy generation through renewable energy sources
- Y02E10/50—Photovoltaic [PV] energy
- Y02E10/542—Dye sensitized solar cells
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Radiation-Therapy Devices (AREA)
- Plural Heterocyclic Compounds (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cosmetics (AREA)
- Detergent Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063008476P | 2020-04-10 | 2020-04-10 | |
| US202063008502P | 2020-04-10 | 2020-04-10 | |
| PCT/US2021/026705 WO2021207691A1 (en) | 2020-04-10 | 2021-04-09 | Phthalocyanine dye compounds, conjugates and methods of use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022020521A2 true BR112022020521A2 (pt) | 2023-03-07 |
Family
ID=78022788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022020521A BR112022020521A2 (pt) | 2020-04-10 | 2021-04-09 | Compostos de corante ftalocianina, conjugados e métodos de uso dos mesmos |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US11466158B2 (enExample) |
| EP (1) | EP4132583A4 (enExample) |
| JP (3) | JP7125828B2 (enExample) |
| KR (1) | KR20230009890A (enExample) |
| CN (1) | CN115942958A (enExample) |
| AU (1) | AU2021251873A1 (enExample) |
| BR (1) | BR112022020521A2 (enExample) |
| CA (1) | CA3179937A1 (enExample) |
| MX (1) | MX2022012721A (enExample) |
| WO (1) | WO2021207691A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115003679A (zh) * | 2020-02-05 | 2022-09-02 | 国立大学法人东京大学 | 酞菁染料与抗体或肽的缀合物 |
| BR112022020521A2 (pt) | 2020-04-10 | 2023-03-07 | Rakuten Medical Inc | Compostos de corante ftalocianina, conjugados e métodos de uso dos mesmos |
| WO2022182483A1 (en) | 2021-02-02 | 2022-09-01 | Rakuten Medical, Inc. | Methods for local and systemic treatment of cancers, tumors and tumor cells |
| EP4319817A4 (en) * | 2021-04-09 | 2026-05-27 | Rakuten Medical Inc | PHTHALOCYANINE-BASED COLOUR COMPOUNDS, CONJUGATES AND ASSOCIATED PROCESSES OF USE |
| US12115223B2 (en) | 2021-04-22 | 2024-10-15 | The University Of Tokyo | Conjugate of biotin-modified dimer and phthalocyanine dye |
| CN113943305B (zh) * | 2021-11-15 | 2022-12-30 | 中国科学技术大学 | 酞菁荧光分子化合物、制备方法、酞菁荧光纳米材料 |
| CA3252736A1 (en) | 2022-02-18 | 2023-08-24 | Rakuten Medical, Inc. | Anti-PD-L1 (Programmed Death-Ligand 1) Antibody Molecules, Coding Polynucleotides, and Methods of Use |
| US20260176317A1 (en) | 2022-11-11 | 2026-06-25 | Rakuten Medical, Inc. | Engineered interleukin-15 polypeptides, complexes and uses thereof |
| EP4435060A1 (en) | 2023-03-23 | 2024-09-25 | Albert-Ludwigs-Universität Freiburg | Silicon phthalocyanine and tribenzophthalocyanine dyes and their use in diagnosis and therapy |
| WO2025035196A1 (pt) * | 2023-08-11 | 2025-02-20 | Use Phitta Cream Ltda - Epp | Creme hidratante com proteção antisséptica de ação prolongada para as mãos |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3710795A (en) | 1970-09-29 | 1973-01-16 | Alza Corp | Drug-delivery device with stretched, rate-controlling membrane |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US6060598A (en) * | 1990-05-15 | 2000-05-09 | Hyperion, Inc. | Fluorescence immunoassays using fluorescent dyes free of aggregation and serum binding |
| CA2082934C (en) * | 1990-05-15 | 2003-08-05 | Walter B. Dandliker | Phthalocyanatopolyethylene glycol, and phthalocyanato saccharides as fluorescent digoxin reagents |
| ATE206395T1 (de) | 1990-05-15 | 2001-10-15 | Hyperion Inc | Fluoreszierende porphyrin- und fluoreszierende phthalocyanin-polyethylenglykol-, polyol- und saccharidderivate als fluoreszierende sonden |
| US5484778C1 (en) * | 1990-07-17 | 2001-05-08 | Univ Cleveland Hospitals | Phthalocynine photosensitizers for photodynamic therapy and methods for their use |
| US5763602A (en) * | 1996-10-01 | 1998-06-09 | Li; Ying-Syi | Methods of syntheses of phthalocyanine compounds |
| US7005518B2 (en) | 2002-10-25 | 2006-02-28 | Li-Cor, Inc. | Phthalocyanine dyes |
| CN1315850C (zh) | 2004-06-11 | 2007-05-16 | 福州大学 | 轴向取代酞菁配合物、它的制备及其在光动力治疗中的应用 |
| CN103539799B (zh) | 2013-08-29 | 2016-01-06 | 中国医学科学院生物医学工程研究所 | 一种水溶性氨基多羧酸修饰酞菁化合物的制备方法和用途 |
| WO2015042325A1 (en) | 2013-09-18 | 2015-03-26 | Aura Biosciences, Inc. | Virus-like particle conjugates for diagnosis and treatment of tumors |
| ES2992591T3 (en) | 2015-08-18 | 2024-12-16 | Rakuten Medical Inc | Compositions, combinations and related methods for photoimmunotherapy |
| ES2999358T3 (en) * | 2015-08-18 | 2025-02-25 | Rakuten Medical Inc | Phthalocyanine dye conjugates and their storage |
| CA3026651A1 (en) | 2016-06-09 | 2017-12-14 | Blinkbio, Inc. | Silanol based therapeutic payloads |
| US10416366B2 (en) | 2016-10-25 | 2019-09-17 | Rakuten Medical, Inc. | Light diffusing devices for use in photoimmunotherapy |
| CN109863346A (zh) | 2016-10-25 | 2019-06-07 | 乐天医药生技股份有限公司 | 用于光免疫治疗的光漫射装置 |
| JP2020508323A (ja) * | 2017-02-23 | 2020-03-19 | ラクテン メディカル インコーポレイテッド | 光免疫療法のための治療用組成物および関連する方法 |
| US11879014B2 (en) | 2017-03-17 | 2024-01-23 | Tusk Therapeutics Ltd. | Method of treating cancer or depleting regulatory T cells in a subject by administering a human IGG1 anti-CD25 antibody |
| WO2019008386A1 (en) | 2017-07-06 | 2019-01-10 | Tusk Therapeutics Ltd | COMPOUNDS AND METHODS FOR DEPLOYING SPECIFIC CELLS FROM A TUMOR |
| JP2020017910A (ja) | 2018-07-27 | 2020-01-30 | ソニーセミコンダクタソリューションズ株式会社 | ストリーキング補正回路、撮像装置、及び、電子機器 |
| JP7625188B2 (ja) * | 2019-09-30 | 2025-02-03 | 国立大学法人 東京大学 | ビオチン改変二量体とフタロシアニン染料とのコンジュゲート |
| CN115003679A (zh) | 2020-02-05 | 2022-09-02 | 国立大学法人东京大学 | 酞菁染料与抗体或肽的缀合物 |
| BR112022020521A2 (pt) | 2020-04-10 | 2023-03-07 | Rakuten Medical Inc | Compostos de corante ftalocianina, conjugados e métodos de uso dos mesmos |
| EP4319817A4 (en) | 2021-04-09 | 2026-05-27 | Rakuten Medical Inc | PHTHALOCYANINE-BASED COLOUR COMPOUNDS, CONJUGATES AND ASSOCIATED PROCESSES OF USE |
-
2021
- 2021-04-09 BR BR112022020521A patent/BR112022020521A2/pt not_active Application Discontinuation
- 2021-04-09 CN CN202180042331.XA patent/CN115942958A/zh active Pending
- 2021-04-09 AU AU2021251873A patent/AU2021251873A1/en active Pending
- 2021-04-09 JP JP2021571480A patent/JP7125828B2/ja active Active
- 2021-04-09 MX MX2022012721A patent/MX2022012721A/es unknown
- 2021-04-09 EP EP21783992.7A patent/EP4132583A4/en active Pending
- 2021-04-09 KR KR1020227039145A patent/KR20230009890A/ko not_active Withdrawn
- 2021-04-09 CA CA3179937A patent/CA3179937A1/en active Pending
- 2021-04-09 WO PCT/US2021/026705 patent/WO2021207691A1/en not_active Ceased
- 2021-09-22 US US17/482,239 patent/US11466158B2/en active Active
-
2022
- 2022-08-08 JP JP2022126602A patent/JP2022191209A/ja active Pending
- 2022-08-12 JP JP2022128871A patent/JP7900220B2/ja active Active
- 2022-09-23 US US17/934,705 patent/US12448518B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CA3179937A1 (en) | 2021-10-14 |
| US20220010140A1 (en) | 2022-01-13 |
| WO2021207691A1 (en) | 2021-10-14 |
| AU2021251873A1 (en) | 2022-11-10 |
| US11466158B2 (en) | 2022-10-11 |
| EP4132583A4 (en) | 2024-11-13 |
| EP4132583A1 (en) | 2023-02-15 |
| JP7900220B2 (ja) | 2026-08-04 |
| CN115942958A (zh) | 2023-04-07 |
| JP2022191210A (ja) | 2022-12-27 |
| MX2022012721A (es) | 2023-01-16 |
| JP2022191209A (ja) | 2022-12-27 |
| JP7125828B2 (ja) | 2022-08-25 |
| KR20230009890A (ko) | 2023-01-17 |
| US12448518B2 (en) | 2025-10-21 |
| US20230399515A1 (en) | 2023-12-14 |
| JP2022527672A (ja) | 2022-06-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |