BR112022017754A2 - Métodos para retardar a perda de volume cerebral - Google Patents

Métodos para retardar a perda de volume cerebral

Info

Publication number
BR112022017754A2
BR112022017754A2 BR112022017754A BR112022017754A BR112022017754A2 BR 112022017754 A2 BR112022017754 A2 BR 112022017754A2 BR 112022017754 A BR112022017754 A BR 112022017754A BR 112022017754 A BR112022017754 A BR 112022017754A BR 112022017754 A2 BR112022017754 A2 BR 112022017754A2
Authority
BR
Brazil
Prior art keywords
methods
brain volume
volume loss
delay
delay brain
Prior art date
Application number
BR112022017754A
Other languages
English (en)
Inventor
Burcklen Michel
Hennessy Brian
Kracker Hilke
Linscheid Philippe
Sidorenko Tatiana
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of BR112022017754A2 publication Critical patent/BR112022017754A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Abstract

MÉTODOS PARA RETARDAR A PERDA DE VOLUME CEREBRAL. A revelação se refere a métodos para retardar a perda de volume cerebral. Em certos aspectos, são revelados métodos para retardar a perda de volume cerebral em um paciente com esclerose múltipla.
BR112022017754A 2020-03-06 2021-03-05 Métodos para retardar a perda de volume cerebral BR112022017754A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202062986171P 2020-03-06 2020-03-06
PCT/EP2021/055622 WO2021176070A1 (en) 2020-03-06 2021-03-05 Methods of slowing brain volume loss

Publications (1)

Publication Number Publication Date
BR112022017754A2 true BR112022017754A2 (pt) 2022-10-18

Family

ID=74859476

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022017754A BR112022017754A2 (pt) 2020-03-06 2021-03-05 Métodos para retardar a perda de volume cerebral

Country Status (10)

Country Link
US (1) US20230123588A1 (pt)
EP (1) EP4114388A1 (pt)
KR (1) KR20220151625A (pt)
AU (1) AU2021232637A1 (pt)
BR (1) BR112022017754A2 (pt)
CA (1) CA3170688A1 (pt)
IL (1) IL295976A (pt)
MX (1) MX2022010962A (pt)
TW (1) TW202146015A (pt)
WO (1) WO2021176070A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3221343A1 (en) 2021-10-11 2023-04-20 Allitia DIBERNARDO Methods of treating multiple sclerosis
CA3220702A1 (en) * 2022-02-11 2023-08-17 Actelion Pharmaceuticals Ltd Methods of slowing an increase in brain ventricular volume

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2854439A1 (de) 1978-12-16 1980-07-03 Hoechst Ag Ein isoxazolderivat, verfahren zu seiner herstellung, diese verbindung enthaltende mittel und verwendung
US4959389A (en) 1987-10-19 1990-09-25 Speiser Peter P Pharmaceutical preparation for the treatment of psoriatic arthritis
DE19853487A1 (de) 1998-11-19 2000-05-25 Fumapharm Ag Muri Verwendung von Dialkylfumaraten
ES2477884T3 (es) 2008-08-19 2014-07-18 Xenoport, Inc. Profármacos de hidrogenofumarato de metilo, composiciones farmacéuticas de los mismos y procedimientos de uso
GB0819182D0 (en) 2008-10-20 2008-11-26 Actelion Pharmaceuticals Ltd Crystalline forms
WO2012061060A1 (en) * 2010-10-25 2012-05-10 Sanofi-Aventis U.S. Llc Use of teriflunomide for treating brain atrophy
SI2970101T1 (sl) 2013-03-14 2018-09-28 Alkermes Pharma Ireland Limited Prozdravila fumaratov in njihova uporaba pri zdravljenju različnih bolezni
PL3256125T3 (pl) 2014-12-11 2022-05-09 Actelion Pharmaceuticals Ltd Schemat dawkowania ponesimodu, selektywnego agonisty receptora s1p1

Also Published As

Publication number Publication date
MX2022010962A (es) 2022-10-07
AU2021232637A1 (en) 2022-09-22
KR20220151625A (ko) 2022-11-15
US20230123588A1 (en) 2023-04-20
WO2021176070A1 (en) 2021-09-10
EP4114388A1 (en) 2023-01-11
TW202146015A (zh) 2021-12-16
CA3170688A1 (en) 2021-09-10
IL295976A (en) 2022-10-01

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