BR112022017574A2 - Compostos que têm como alvo proteínas de ligação ao rna ou proteínas modificadoras de rna - Google Patents
Compostos que têm como alvo proteínas de ligação ao rna ou proteínas modificadoras de rnaInfo
- Publication number
- BR112022017574A2 BR112022017574A2 BR112022017574A BR112022017574A BR112022017574A2 BR 112022017574 A2 BR112022017574 A2 BR 112022017574A2 BR 112022017574 A BR112022017574 A BR 112022017574A BR 112022017574 A BR112022017574 A BR 112022017574A BR 112022017574 A2 BR112022017574 A2 BR 112022017574A2
- Authority
- BR
- Brazil
- Prior art keywords
- rna
- proteins
- compounds
- modifying
- binding proteins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
COMPOSTOS QUE TÊM COMO ALVO PROTEÍNAS DE LIGAÇÃO AO RNA OU PROTEÍNAS MODIFICADORAS DE RNA. A presente invenção refere-se a um composto representado pela Fórmula (I): ou um sal farmaceuticamente aceitável do mesmo, composições que compreendem os mesmos e métodos de preparação e uso dos mesmos. As variáveis são descritas no presente documento.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202062984677P | 2020-03-03 | 2020-03-03 | |
PCT/US2021/020494 WO2021178420A1 (en) | 2020-03-03 | 2021-03-02 | Compounds targeting rna-binding proteins or rna-modifying proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022017574A2 true BR112022017574A2 (pt) | 2022-11-16 |
Family
ID=75223420
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022017574A BR112022017574A2 (pt) | 2020-03-03 | 2021-03-02 | Compostos que têm como alvo proteínas de ligação ao rna ou proteínas modificadoras de rna |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP4114831A1 (pt) |
JP (1) | JP2023517539A (pt) |
KR (1) | KR20230022829A (pt) |
CN (1) | CN116157392A (pt) |
AU (1) | AU2021231765A1 (pt) |
BR (1) | BR112022017574A2 (pt) |
CA (1) | CA3170415A1 (pt) |
IL (1) | IL296137A (pt) |
MX (1) | MX2022010957A (pt) |
TW (1) | TW202146398A (pt) |
WO (1) | WO2021178420A1 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2023137325A (ja) * | 2022-03-18 | 2023-09-29 | 日清食品ホールディングス株式会社 | 2-アセチル-1-ピロリンの製造方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US756011A (en) | 1903-06-01 | 1904-03-29 | James L Fitz Gerald | Gasolene-motor. |
RU2139351C1 (ru) | 1991-04-25 | 1999-10-10 | Чугаи Сейяку Кабусики Кайся | Н- и l-цепи моноклонального антитела рм1 (монат) к рецептору il-6r человека и их v-области, модифицированная монат, его н- и l-цепи и их v-области, cdr- последовательности, днк-последовательности |
TWI440469B (zh) | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
WO2017156557A1 (en) | 2016-03-07 | 2017-09-14 | Northeast Ohio Medical University | Animal model for studying zcchc6 in bone disease and development |
WO2017153952A1 (en) | 2016-03-10 | 2017-09-14 | Glaxosmithkline Intellectual Property Development Limited | 5-sulfamoyl-2-hydroxybenzamide derivatives |
WO2018005608A1 (en) | 2016-06-28 | 2018-01-04 | Northeast Ohio Medical University | Compositions and methods for preventing bone loss and/or stimulating bone healing |
-
2021
- 2021-03-02 CA CA3170415A patent/CA3170415A1/en active Pending
- 2021-03-02 KR KR1020227034193A patent/KR20230022829A/ko active Search and Examination
- 2021-03-02 BR BR112022017574A patent/BR112022017574A2/pt unknown
- 2021-03-02 EP EP21714486.4A patent/EP4114831A1/en active Pending
- 2021-03-02 AU AU2021231765A patent/AU2021231765A1/en active Pending
- 2021-03-02 IL IL296137A patent/IL296137A/en unknown
- 2021-03-02 MX MX2022010957A patent/MX2022010957A/es unknown
- 2021-03-02 WO PCT/US2021/020494 patent/WO2021178420A1/en unknown
- 2021-03-02 CN CN202180032685.6A patent/CN116157392A/zh active Pending
- 2021-03-02 JP JP2022553050A patent/JP2023517539A/ja active Pending
- 2021-03-03 TW TW110107621A patent/TW202146398A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP4114831A1 (en) | 2023-01-11 |
KR20230022829A (ko) | 2023-02-16 |
WO2021178420A1 (en) | 2021-09-10 |
IL296137A (en) | 2022-11-01 |
TW202146398A (zh) | 2021-12-16 |
JP2023517539A (ja) | 2023-04-26 |
AU2021231765A1 (en) | 2022-10-06 |
MX2022010957A (es) | 2023-01-24 |
CA3170415A1 (en) | 2021-09-10 |
CN116157392A (zh) | 2023-05-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved |
Owner name: REDONA THERAPEUTICS, INC. (US) |