BR112022016268A2 - Composições imunogênicas de strep do grupo a com conjugados de polisacarídeo-proteína - Google Patents
Composições imunogênicas de strep do grupo a com conjugados de polisacarídeo-proteínaInfo
- Publication number
- BR112022016268A2 BR112022016268A2 BR112022016268A BR112022016268A BR112022016268A2 BR 112022016268 A2 BR112022016268 A2 BR 112022016268A2 BR 112022016268 A BR112022016268 A BR 112022016268A BR 112022016268 A BR112022016268 A BR 112022016268A BR 112022016268 A2 BR112022016268 A2 BR 112022016268A2
- Authority
- BR
- Brazil
- Prior art keywords
- group
- polysaccharide
- immunogenic compositions
- strep
- protein conjugates
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000002163 immunogen Effects 0.000 title abstract 3
- 241001505901 Streptococcus sp. 'group A' Species 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0283—Shigella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/2111—C5a peptidase (3.4.21.110)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6087—Polysaccharides; Lipopolysaccharides [LPS]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/116—Polyvalent bacterial antigens
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062977886P | 2020-02-18 | 2020-02-18 | |
| US202063013924P | 2020-04-22 | 2020-04-22 | |
| US202063090069P | 2020-10-09 | 2020-10-09 | |
| US202063123293P | 2020-12-09 | 2020-12-09 | |
| PCT/US2021/018402 WO2021167996A1 (en) | 2020-02-18 | 2021-02-17 | Group a strep immunogenic compositions with polysaccharide-protein conjugates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022016268A2 true BR112022016268A2 (pt) | 2022-10-11 |
Family
ID=74860575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022016268A BR112022016268A2 (pt) | 2020-02-18 | 2021-02-17 | Composições imunogênicas de strep do grupo a com conjugados de polisacarídeo-proteína |
Country Status (13)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023538365A (ja) | 2020-08-19 | 2023-09-07 | バックスサイト・インコーポレイテッド | 担体－タンパク質多糖結合方法 |
| JP2024506713A (ja) * | 2021-02-17 | 2024-02-14 | バックスサイト・インコーポレイテッド | 多糖およびそのポリペプチドコンジュゲートの精製方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6355255B1 (en) * | 1998-12-07 | 2002-03-12 | Regents Of The University Of Minnesota | Streptococcal C5a peptidase vaccine |
| NZ586430A (en) * | 2007-12-21 | 2012-09-28 | Novartis Ag | Mutant forms of streptolysin o (slo) |
| PT2349520T (pt) | 2008-10-27 | 2016-08-16 | Glaxosmithkline Biologicals Sa | Método de purificação para hidrato de carbono de estreptococos grupo a |
| WO2013020090A2 (en) | 2011-08-04 | 2013-02-07 | The Regents Of The University Of California | STREPTOCOCCAL GLcNAc-LACKING GLYCOPOLYPEPTIDES, CELL WALL CARBOHYDRATES, STREPTOCOCCUS VACCINES, AND METHODS FOR MAKING AND USING THEM |
| AU2013320313B2 (en) * | 2012-09-18 | 2018-07-12 | Glaxosmithkline Biologicals Sa | Outer membrane vesicles |
| IL267709B2 (en) * | 2016-12-30 | 2025-04-01 | Vaxcyte Inc | Polypeptide-antigen conjugates with unnatural amino acids |
-
2021
- 2021-02-17 CN CN202180015475.6A patent/CN115175697A/zh active Pending
- 2021-02-17 EP EP21710835.6A patent/EP4106807A1/en active Pending
- 2021-02-17 IL IL295702A patent/IL295702A/en unknown
- 2021-02-17 BR BR112022016268A patent/BR112022016268A2/pt not_active Application Discontinuation
- 2021-02-17 JP JP2022549495A patent/JP2023514332A/ja active Pending
- 2021-02-17 AU AU2021224585A patent/AU2021224585A1/en active Pending
- 2021-02-17 CA CA3168201A patent/CA3168201A1/en active Pending
- 2021-02-17 MX MX2022010129A patent/MX2022010129A/es unknown
- 2021-02-17 TW TW110105419A patent/TW202136285A/zh unknown
- 2021-02-17 PH PH1/2022/552118A patent/PH12022552118A1/en unknown
- 2021-02-17 WO PCT/US2021/018402 patent/WO2021167996A1/en not_active Ceased
- 2021-02-17 KR KR1020227032307A patent/KR20220143107A/ko active Pending
-
2022
- 2022-08-17 US US17/820,554 patent/US20230293658A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX2022010129A (es) | 2022-09-05 |
| TW202136285A (zh) | 2021-10-01 |
| CN115175697A (zh) | 2022-10-11 |
| IL295702A (en) | 2022-10-01 |
| AU2021224585A1 (en) | 2022-10-13 |
| PH12022552118A1 (en) | 2024-01-29 |
| EP4106807A1 (en) | 2022-12-28 |
| WO2021167996A1 (en) | 2021-08-26 |
| JP2023514332A (ja) | 2023-04-05 |
| US20230293658A1 (en) | 2023-09-21 |
| KR20220143107A (ko) | 2022-10-24 |
| CA3168201A1 (en) | 2021-08-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |