BR112022009932A2 - Método de produção de toxina botulínica. - Google Patents

Método de produção de toxina botulínica.

Info

Publication number
BR112022009932A2
BR112022009932A2 BR112022009932A BR112022009932A BR112022009932A2 BR 112022009932 A2 BR112022009932 A2 BR 112022009932A2 BR 112022009932 A BR112022009932 A BR 112022009932A BR 112022009932 A BR112022009932 A BR 112022009932A BR 112022009932 A2 BR112022009932 A2 BR 112022009932A2
Authority
BR
Brazil
Prior art keywords
botulinum toxin
production method
toxin production
present disclosure
free
Prior art date
Application number
BR112022009932A
Other languages
English (en)
Inventor
Stahl Ulf
Frank Peter
Jarstad Anders
Pickett Andrew
Original Assignee
Galderma Holding SA
Ipsen Biopharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Holding SA, Ipsen Biopharm Ltd filed Critical Galderma Holding SA
Publication of BR112022009932A2 publication Critical patent/BR112022009932A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/145—Clostridium

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

MÉTODO DE PRODUÇÃO DE TOXINA BOTULÍNICA. A presente divulgação se refere de maneira geral ao campo de produção de toxina botulínica. Mais especificamente, a presente divulgação refere-se a um método para produzir toxina botulínica em um meio de cultura livre ou substancialmente livre de produto animal. A presente divulgação também se refere ao meio de cultura para produção de toxina botulínica que é livre ou substancialmente livre de produto animal.
BR112022009932A 2019-12-20 2020-12-19 Método de produção de toxina botulínica. BR112022009932A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962951549P 2019-12-20 2019-12-20
PCT/IB2020/062252 WO2021124296A1 (en) 2019-12-20 2020-12-19 Method of producing botulinum toxin

Publications (1)

Publication Number Publication Date
BR112022009932A2 true BR112022009932A2 (pt) 2022-08-09

Family

ID=74004131

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022009932A BR112022009932A2 (pt) 2019-12-20 2020-12-19 Método de produção de toxina botulínica.

Country Status (13)

Country Link
US (1) US20220356440A1 (pt)
EP (1) EP4077706A1 (pt)
JP (1) JP2023507654A (pt)
KR (1) KR20220140696A (pt)
CN (1) CN114945678A (pt)
AU (1) AU2020407634A1 (pt)
BR (1) BR112022009932A2 (pt)
CA (1) CA3158105A1 (pt)
GE (1) GEP20247609B (pt)
IL (1) IL292927A (pt)
MX (1) MX2022007600A (pt)
TW (1) TW202136518A (pt)
WO (1) WO2021124296A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102209159B1 (ko) * 2019-03-29 2021-01-29 (주)제테마 독소의 제조방법
KR20240041474A (ko) * 2022-09-23 2024-04-01 (주)제테마 보툴리눔 독소 생산성을 증가시키는 방법

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1913205A (en) 1927-12-27 1933-06-06 Sherer Gillett Company Antifogging device
CA962933A (en) 1969-12-05 1975-02-18 Yutaka Hori Metal foil-plastic laminated film and method of producing the same
AU2431995A (en) 1994-05-09 1995-11-29 William J. Binder Method for reduction of headache pain
US6921538B2 (en) 2002-05-10 2005-07-26 Allergan, Inc. Therapeutic treatments for neuropsychiatric disorders
US20040235139A1 (en) * 2002-12-23 2004-11-25 Demain Arnold L. Clostridium difficile culture and toxin production methods
US7148041B2 (en) * 2003-09-25 2006-12-12 Allergan, Inc. Animal product free media and processes for obtaining a botulinum toxin
US9078892B2 (en) 2004-02-26 2015-07-14 Allergan, Inc. Methods for treating pain and for treating a medication overuse disorder
WO2006042542A2 (en) * 2004-10-19 2006-04-27 Statens Serum Institut Production of tetanus, diphtheria, and pertussis toxins and toxoids using fermentation media containing no components of animal or soy origin
US8129139B2 (en) * 2009-07-13 2012-03-06 Allergan, Inc. Process for obtaining botulinum neurotoxin
KR101723167B1 (ko) * 2015-04-28 2017-04-05 주식회사 대웅 보툴리눔 독소의 제조를 위한 배지 조성물
US20210108187A1 (en) * 2017-04-28 2021-04-15 Bonti, Inc. Botulinum neurotoxins production methods

Also Published As

Publication number Publication date
EP4077706A1 (en) 2022-10-26
GEP20247609B (en) 2024-03-11
CN114945678A (zh) 2022-08-26
IL292927A (en) 2022-07-01
CA3158105A1 (en) 2021-06-24
KR20220140696A (ko) 2022-10-18
WO2021124296A1 (en) 2021-06-24
JP2023507654A (ja) 2023-02-24
US20220356440A1 (en) 2022-11-10
MX2022007600A (es) 2022-07-19
TW202136518A (zh) 2021-10-01
AU2020407634A1 (en) 2022-06-09

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Legal Events

Date Code Title Description
B25G Requested change of headquarter approved

Owner name: GALDERMA HOLDING SA (CH) ; IPSEN BIOPHARM LIMITED (GB)