BR112022008046A2 - Composto químico 9-oxoacridinil-10-acetato de l-lisina - Google Patents
Composto químico 9-oxoacridinil-10-acetato de l-lisinaInfo
- Publication number
- BR112022008046A2 BR112022008046A2 BR112022008046A BR112022008046A BR112022008046A2 BR 112022008046 A2 BR112022008046 A2 BR 112022008046A2 BR 112022008046 A BR112022008046 A BR 112022008046A BR 112022008046 A BR112022008046 A BR 112022008046A BR 112022008046 A2 BR112022008046 A2 BR 112022008046A2
- Authority
- BR
- Brazil
- Prior art keywords
- oxoacridinyl
- chemical compound
- acetate
- lysine
- lysine acetate
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 229960005357 lysine acetate Drugs 0.000 title 1
- KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 abstract 5
- 102000004083 Lymphotoxin-alpha Human genes 0.000 abstract 3
- 108090000542 Lymphotoxin-alpha Proteins 0.000 abstract 3
- 230000000259 anti-tumor effect Effects 0.000 abstract 3
- 102000003898 interleukin-24 Human genes 0.000 abstract 3
- 108090000237 interleukin-24 Proteins 0.000 abstract 3
- 235000019766 L-Lysine Nutrition 0.000 abstract 2
- 239000004472 Lysine Substances 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 230000000771 oncological effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/06—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2019134800A RU2730530C1 (ru) | 2019-10-29 | 2019-10-29 | Новое химическое соединение L-лизина 9-оксоакридинил-10-ацетат, стимулирующее продукцию интерлейкина-24 и фактора некроза опухолей - бета |
| PCT/RU2020/050289 WO2021086234A1 (ru) | 2019-10-29 | 2020-10-22 | Новое химическое соединение l-лизина 9-оксоакридинил-10-ацетат |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022008046A2 true BR112022008046A2 (pt) | 2022-07-12 |
Family
ID=72235056
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022008046A BR112022008046A2 (pt) | 2019-10-29 | 2020-10-22 | Composto químico 9-oxoacridinil-10-acetato de l-lisina |
Country Status (9)
| Country | Link |
|---|---|
| CN (1) | CN114901643B (ru) |
| BR (1) | BR112022008046A2 (ru) |
| CO (1) | CO2022007317A2 (ru) |
| EA (1) | EA035914B1 (ru) |
| EC (1) | ECSP22041864A (ru) |
| GE (1) | GEP20237566B (ru) |
| MD (1) | MD20220026A2 (ru) |
| RU (1) | RU2730530C1 (ru) |
| WO (1) | WO2021086234A1 (ru) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2326115C2 (ru) * | 2005-11-21 | 2008-06-10 | Ефаг АО | Соли 1-алкиламино-1-дезоксиполиолов с 9-оксоакридин-10-уксусной кислотой, лекарственные препараты на их основе, применение, способы профилактики и лечения |
| RU2325160C1 (ru) * | 2006-07-31 | 2008-05-27 | Ефаг АО | Средство для лечения рака предстательной железы и профилактики его рецидива |
| RU2346692C2 (ru) * | 2007-03-29 | 2009-02-20 | Ефаг АО | Применение 9-оксоакридин-10-уксусной кислоты, ее солей и сложных эфиров в комбинированной терапии рака яичников, способ лечения и наборы |
| RU2363466C2 (ru) * | 2007-03-29 | 2009-08-10 | АО Ефаг | Способ и набор для лечения и профилактики злокачественных опухолей женской репродуктивной системы с применением 9-оксоакридин-10-уксусной кислоты, и/или ее соли, и/или ее сложного эфира |
| MX2020004902A (es) * | 2017-11-20 | 2020-09-09 | Silicon Swat Inc | Derivados del acido oxoacridinilo acetico y metodos de uso. |
-
2019
- 2019-10-29 RU RU2019134800A patent/RU2730530C1/ru active
-
2020
- 2020-02-18 EA EA202000071A patent/EA035914B1/ru unknown
- 2020-10-22 WO PCT/RU2020/050289 patent/WO2021086234A1/ru active Application Filing
- 2020-10-22 CN CN202080090822.7A patent/CN114901643B/zh active Active
- 2020-10-22 GE GEAP202015959A patent/GEP20237566B/en unknown
- 2020-10-22 MD MDA20220026A patent/MD20220026A2/ru unknown
- 2020-10-22 BR BR112022008046A patent/BR112022008046A2/pt unknown
-
2022
- 2022-05-25 EC ECSENADI202241864A patent/ECSP22041864A/es unknown
- 2022-05-28 CO CONC2022/0007317A patent/CO2022007317A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EA035914B1 (ru) | 2020-08-31 |
| EA202000071A1 (ru) | 2020-08-28 |
| CN114901643B (zh) | 2024-06-25 |
| CN114901643A (zh) | 2022-08-12 |
| RU2730530C1 (ru) | 2020-08-24 |
| CO2022007317A2 (es) | 2022-06-21 |
| GEP20237566B (en) | 2023-11-10 |
| ECSP22041864A (es) | 2022-08-31 |
| MD20220026A2 (ru) | 2022-09-30 |
| WO2021086234A1 (ru) | 2021-05-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4A ANUIDADE. |