BR112022001567A2 - Derivados de isoquinolina e seu uso para o tratamento de infecções parasitárias. - Google Patents

Derivados de isoquinolina e seu uso para o tratamento de infecções parasitárias.

Info

Publication number
BR112022001567A2
BR112022001567A2 BR112022001567A BR112022001567A BR112022001567A2 BR 112022001567 A2 BR112022001567 A2 BR 112022001567A2 BR 112022001567 A BR112022001567 A BR 112022001567A BR 112022001567 A BR112022001567 A BR 112022001567A BR 112022001567 A2 BR112022001567 A2 BR 112022001567A2
Authority
BR
Brazil
Prior art keywords
compounds
treatment
parasitic infections
isoquinoline derivatives
preparing
Prior art date
Application number
BR112022001567A
Other languages
English (en)
Inventor
Bernd Alig
Claudia Böhm
Daniel Kulke
Hans-Georg Schwarz
Iring Heisler
Jana Irina Janssen Isa
Kirsten Börngen
Nils Griebenow
Walter Hübsch
Wei Zhuang
Original Assignee
Bayer Animal Health Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Animal Health Gmbh filed Critical Bayer Animal Health Gmbh
Publication of BR112022001567A2 publication Critical patent/BR112022001567A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

derivados de isoquinolina e seu uso para o tratamento de infecções parasitárias. a presente invenção abrange novos compostos de isoquinolina da fórmula geral (i): em que a, r1, r2, r3, r4, r5, r6 e q são como aqui definidos, métodos para preparar os referidos compostos, compostos intermediários úteis para preparar os referidos compostos, composições farmacêuticas e combinações compreendendo os referidos compostos e o uso dos referidos compostos para fabricar composições farmacêuticas para tratamento, controle e/ou prevenção de doenças, em particular de infecções de helmintos, como um agente único ou em combinação com outros ingredientes ativos.
BR112022001567A 2019-07-30 2020-07-27 Derivados de isoquinolina e seu uso para o tratamento de infecções parasitárias. BR112022001567A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19189099 2019-07-30
PCT/EP2020/071139 WO2021018839A1 (en) 2019-07-30 2020-07-27 Isoquinoline derivatives and their use for the treatment of parasitic infections

Publications (1)

Publication Number Publication Date
BR112022001567A2 true BR112022001567A2 (pt) 2022-04-12

Family

ID=67513381

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022001567A BR112022001567A2 (pt) 2019-07-30 2020-07-27 Derivados de isoquinolina e seu uso para o tratamento de infecções parasitárias.

Country Status (10)

Country Link
US (1) US20220274971A1 (pt)
EP (1) EP4003524A1 (pt)
JP (1) JP2022542682A (pt)
CN (1) CN114423749A (pt)
AU (1) AU2020321572A1 (pt)
BR (1) BR112022001567A2 (pt)
CA (1) CA3147542A1 (pt)
TW (1) TW202120490A (pt)
UY (1) UY38816A (pt)
WO (1) WO2021018839A1 (pt)

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AU2022377394A1 (en) 2021-11-01 2024-06-13 Boehringer Ingelheim Vetmedica Gmbh Anthelmintic pyrrolopyridazine compounds

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Also Published As

Publication number Publication date
CN114423749A (zh) 2022-04-29
JP2022542682A (ja) 2022-10-06
US20220274971A1 (en) 2022-09-01
TW202120490A (zh) 2021-06-01
UY38816A (es) 2021-02-26
AU2020321572A1 (en) 2022-02-17
EP4003524A1 (en) 2022-06-01
WO2021018839A1 (en) 2021-02-04
CA3147542A1 (en) 2021-02-04

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