BR112021026812A2 - Ligantes de antígeno de membrana específico da próstata (psma) e usos dos mesmos - Google Patents

Ligantes de antígeno de membrana específico da próstata (psma) e usos dos mesmos

Info

Publication number
BR112021026812A2
BR112021026812A2 BR112021026812A BR112021026812A BR112021026812A2 BR 112021026812 A2 BR112021026812 A2 BR 112021026812A2 BR 112021026812 A BR112021026812 A BR 112021026812A BR 112021026812 A BR112021026812 A BR 112021026812A BR 112021026812 A2 BR112021026812 A2 BR 112021026812A2
Authority
BR
Brazil
Prior art keywords
psma
ligands
specific membrane
membrane antigen
prostate specific
Prior art date
Application number
BR112021026812A
Other languages
English (en)
Portuguese (pt)
Inventor
Daniela Chicco
Lorenza Fugazza
Gilbert Pomper Martin
F Mariani Maurizio
Sangeeta Ray
Original Assignee
Advanced Accelerator Applications Italy Srl
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Accelerator Applications Italy Srl, Univ Johns Hopkins filed Critical Advanced Accelerator Applications Italy Srl
Publication of BR112021026812A2 publication Critical patent/BR112021026812A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0497Organic compounds conjugates with a carrier being an organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0402Organic compounds carboxylic acid carriers, fatty acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
BR112021026812A 2019-07-02 2020-06-30 Ligantes de antígeno de membrana específico da próstata (psma) e usos dos mesmos BR112021026812A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19184015 2019-07-02
PCT/EP2020/068386 WO2021001360A1 (en) 2019-07-02 2020-06-30 Prostate specific membrane antigen (psma) ligands and uses thereof

Publications (1)

Publication Number Publication Date
BR112021026812A2 true BR112021026812A2 (pt) 2022-02-22

Family

ID=67145647

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021026812A BR112021026812A2 (pt) 2019-07-02 2020-06-30 Ligantes de antígeno de membrana específico da próstata (psma) e usos dos mesmos

Country Status (15)

Country Link
US (1) US20230226227A1 (es)
EP (1) EP3993837A1 (es)
JP (1) JP2022538478A (es)
KR (1) KR20220044496A (es)
CN (1) CN114341118A (es)
AR (1) AR119331A1 (es)
AU (2) AU2020299974A1 (es)
BR (1) BR112021026812A2 (es)
CA (1) CA3144557A1 (es)
CL (1) CL2021003525A1 (es)
CO (1) CO2021017708A2 (es)
IL (1) IL289039A (es)
MX (1) MX2022000136A (es)
TW (1) TW202114742A (es)
WO (1) WO2021001360A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115484991A (zh) * 2020-04-29 2022-12-16 诺华股份有限公司 用于放射性标记psma结合配体的方法及其试剂盒

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2415709A1 (en) 2000-07-11 2003-01-10 Bml, Inc. Remedies for bone diseases
DE202014011600U1 (de) * 2013-10-18 2023-05-31 Deutsches Krebsforschungszentrum, Stiftung Des Öffentlichen Rechts Markierte Inhibitoren des prostataspezifischen Membranantigens (PSMA), deren Verwendung als bildgebende Mittel und pharmazeutische Wirkstoffe für die Behandlung von Prostatakrebs
CN114716387A (zh) * 2016-03-22 2022-07-08 约翰霍普金斯大学 用于前列腺癌的腔内放射疗法的前列腺特异性膜抗原靶向的高亲和力剂
WO2018222778A1 (en) * 2017-05-30 2018-12-06 The Johns Hopkins University Prostate-specific membrane antigen targeted high-affinity agents for endoradiotherapy of prostate cancer
IL276528B1 (en) * 2018-02-06 2024-07-01 Univ Johns Hopkins Halogen-labeled urea-polyaminocarboxylates targeting PSMA for cancer radiotherapy
US20210338846A1 (en) * 2018-07-30 2021-11-04 The Johns Hopkins University Competitive prostate-specific membrane antigen (psma) binding agents for reduction of non-target organ uptake of radiolabeled psma inhibitors for psma positive tumor imaging and radiopharmaceutical therapy

Also Published As

Publication number Publication date
IL289039A (en) 2022-02-01
EP3993837A1 (en) 2022-05-11
CO2021017708A2 (es) 2022-05-20
CN114341118A (zh) 2022-04-12
CL2021003525A1 (es) 2022-10-21
US20230226227A1 (en) 2023-07-20
WO2021001360A1 (en) 2021-01-07
KR20220044496A (ko) 2022-04-08
AR119331A1 (es) 2021-12-09
AU2024200850A1 (en) 2024-02-29
CA3144557A1 (en) 2021-01-07
MX2022000136A (es) 2022-04-27
AU2020299974A1 (en) 2022-01-27
JP2022538478A (ja) 2022-09-02
TW202114742A (zh) 2021-04-16

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