BR112021026579A2 - Método de cultivo heterotrófico de euglena gracilis, biorreator para micro-organismos em crescimento heterotrófico, sistema para produção de biomassa e método de cultivo heterotrófico de um micro-organismo - Google Patents

Método de cultivo heterotrófico de euglena gracilis, biorreator para micro-organismos em crescimento heterotrófico, sistema para produção de biomassa e método de cultivo heterotrófico de um micro-organismo

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Publication number
BR112021026579A2
BR112021026579A2 BR112021026579A BR112021026579A BR112021026579A2 BR 112021026579 A2 BR112021026579 A2 BR 112021026579A2 BR 112021026579 A BR112021026579 A BR 112021026579A BR 112021026579 A BR112021026579 A BR 112021026579A BR 112021026579 A2 BR112021026579 A2 BR 112021026579A2
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BR
Brazil
Prior art keywords
heterotrophic
microorganism
cultivation
bioreactor
microorganisms
Prior art date
Application number
BR112021026579A
Other languages
English (en)
Inventor
J Noble Adam
John Bayrak Alexander
Bijaya Uprety
Anthony Castiglione Lee
Zahid Sharif Mostafa
Paul-Philippe Champagne
Richard Cullen Ryan
Cameron Farrow Scott
Original Assignee
Noblegen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noblegen Inc filed Critical Noblegen Inc
Publication of BR112021026579A2 publication Critical patent/BR112021026579A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/02—Atmosphere, e.g. low oxygen conditions

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Thermal Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

método de cultivo heterotrófico de euglena gracilis, biorreator para micro-organismos em crescimento heterotrófico, sistema para produção de biomassa e método de cultivo heterotrófico de um micro-organismo. as concretizações aqui são direcionadas a métodos de cultivo heterotroficamente a. as concretizações neste documento são direcionadas a métodos, sistemas e biorreatores para cultivo heterotroficamente de micro-organismo euglena sp., um micro-organismo schizochytrium sp., ou micro-organismo chlorella sp. compreendendo: cultivar o micro-organismo em um meio de cultura contendo uma ou mais fontes de carbono, uma ou mais fontes de nitrogênio e um ou mais sal; manter um ph entre cerca de 2,0 a cerca de 4,0; manter uma temperatura de cerca de 20ºc a cerca de 30ºc; e manter um ambiente praticamente sem luz; em que a cultura ocorre em três estágios de cultivo.
BR112021026579A 2019-06-28 2020-06-29 Método de cultivo heterotrófico de euglena gracilis, biorreator para micro-organismos em crescimento heterotrófico, sistema para produção de biomassa e método de cultivo heterotrófico de um micro-organismo BR112021026579A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962868589P 2019-06-28 2019-06-28
US201962868343P 2019-06-28 2019-06-28
US201962954837P 2019-12-30 2019-12-30
PCT/IB2020/056135 WO2020261244A1 (en) 2019-06-28 2020-06-29 Methods of optimized euglena fermentation using engineered tank design

Publications (1)

Publication Number Publication Date
BR112021026579A2 true BR112021026579A2 (pt) 2022-02-15

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021026579A BR112021026579A2 (pt) 2019-06-28 2020-06-29 Método de cultivo heterotrófico de euglena gracilis, biorreator para micro-organismos em crescimento heterotrófico, sistema para produção de biomassa e método de cultivo heterotrófico de um micro-organismo

Country Status (8)

Country Link
US (1) US20220259551A1 (pt)
EP (1) EP3990619A1 (pt)
JP (1) JP2022538283A (pt)
CN (1) CN114302950A (pt)
BR (1) BR112021026579A2 (pt)
CA (1) CA3143895A1 (pt)
MX (1) MX2021016018A (pt)
WO (1) WO2020261244A1 (pt)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101633894B (zh) * 2009-08-20 2010-12-01 北京芳能科技有限公司 一种纤细裸藻的培养基及其开放式高密度养殖方法
EP3097201B1 (fr) * 2014-01-20 2018-11-28 Corbion Biotech, Inc. Procédé d'enrichissement en protéines de la biomasse de microalgues
CN108359608A (zh) * 2018-03-08 2018-08-03 青岛旭能生物工程有限责任公司 一种高密度发酵培养纤细裸藻的方法

Also Published As

Publication number Publication date
MX2021016018A (es) 2022-03-11
CA3143895A1 (en) 2020-12-30
EP3990619A1 (en) 2022-05-04
CN114302950A (zh) 2022-04-08
JP2022538283A (ja) 2022-09-01
WO2020261244A1 (en) 2020-12-30
US20220259551A1 (en) 2022-08-18

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