BR112021024540A2 - Métodos para selecionar uma célula ou um vírus, determinar a sequência de um ácido nucleico, produzir uma célula que expressa um ácido nucleico e tratar um sujeito, célula imune selecionada e método para selecionar uma célula imune - Google Patents

Métodos para selecionar uma célula ou um vírus, determinar a sequência de um ácido nucleico, produzir uma célula que expressa um ácido nucleico e tratar um sujeito, célula imune selecionada e método para selecionar uma célula imune

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Publication number
BR112021024540A2
BR112021024540A2 BR112021024540A BR112021024540A BR112021024540A2 BR 112021024540 A2 BR112021024540 A2 BR 112021024540A2 BR 112021024540 A BR112021024540 A BR 112021024540A BR 112021024540 A BR112021024540 A BR 112021024540A BR 112021024540 A2 BR112021024540 A2 BR 112021024540A2
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Prior art keywords
cell
nucleic acid
selecting
antigen
expresses
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BR112021024540A
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English (en)
Inventor
Amir Alpert
Claudia Wagner
Dominik Maurer
Gisela Schimmack
Heiko Schuster
Sara Yousef
Sebastian Bunk
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Immatics Biotechnologies Gmbh
Immatics Us Inc
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Application filed by Immatics Biotechnologies Gmbh, Immatics Us Inc filed Critical Immatics Biotechnologies Gmbh
Publication of BR112021024540A2 publication Critical patent/BR112021024540A2/pt

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Abstract

métodos para selecionar uma célula ou um vírus, determinar a sequência de um ácido nucleico, produzir uma célula que expressa um ácido nucleico e tratar um sujeito, célula imune selecionada e método para selecionar uma célula imune. a presente invenção refere-se a um método para selecionar uma célula ou um vírus que expressa em sua superfície uma proteína de ligação ao antígeno que se liga especificamente a um antígeno de proteína de interesse (pai), enquanto se aplica contrasseleção usando um antígeno de proteína semelhante (spa). além disso, a invenção fornece um método para determinar a sequência de um ácido nucleico que codifica uma proteína de ligação ao antígeno ou uma parte de ligação ao antígeno da mesma e um método para a produção de uma célula que expressa um ácido nucleico que codifica uma proteína de ligação ao antígeno ou uma parte de ligação ao antígeno parte da mesma. a invenção também refere-se a um método para tratar um sujeito com uma população de células selecionada.
BR112021024540A 2019-06-06 2020-06-04 Métodos para selecionar uma célula ou um vírus, determinar a sequência de um ácido nucleico, produzir uma célula que expressa um ácido nucleico e tratar um sujeito, célula imune selecionada e método para selecionar uma célula imune BR112021024540A2 (pt)

Applications Claiming Priority (3)

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US201962858167P 2019-06-06 2019-06-06
DE102019129341 2019-10-30
PCT/EP2020/065567 WO2020245326A1 (en) 2019-06-06 2020-06-04 Sorting with counter selection using sequence similar peptides

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BR112021024540A2 true BR112021024540A2 (pt) 2022-03-22

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BR112021024540A BR112021024540A2 (pt) 2019-06-06 2020-06-04 Métodos para selecionar uma célula ou um vírus, determinar a sequência de um ácido nucleico, produzir uma célula que expressa um ácido nucleico e tratar um sujeito, célula imune selecionada e método para selecionar uma célula imune

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US (2) US20200384028A1 (pt)
EP (2) EP3980776A1 (pt)
JP (2) JP2022535421A (pt)
KR (2) KR20220018006A (pt)
CN (2) CN114303060A (pt)
AU (2) AU2020286756A1 (pt)
BR (1) BR112021024540A2 (pt)
CA (2) CA3142386A1 (pt)
IL (1) IL288704A (pt)
MX (2) MX2021015033A (pt)
SG (2) SG11202112561UA (pt)
TW (2) TW202112805A (pt)
WO (2) WO2020245326A1 (pt)

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DE102018107224A1 (de) 2018-02-21 2019-08-22 Immatics Biotechnologies Gmbh Peptide und Kombinationen von Peptiden nicht-kanonischen Ursprungs zur Verwendung in der Immuntherapie gegen verschiedene Krebsarten
DE102018108612A1 (de) 2018-03-21 2019-09-26 Immatics US, Inc. Verfahren zur erhöhung der persistenz von adoptiv infundierten t-zellen

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