BR112021020429A2 - Método e aparelho para recondicionar rins - Google Patents

Método e aparelho para recondicionar rins

Info

Publication number
BR112021020429A2
BR112021020429A2 BR112021020429A BR112021020429A BR112021020429A2 BR 112021020429 A2 BR112021020429 A2 BR 112021020429A2 BR 112021020429 A BR112021020429 A BR 112021020429A BR 112021020429 A BR112021020429 A BR 112021020429A BR 112021020429 A2 BR112021020429 A2 BR 112021020429A2
Authority
BR
Brazil
Prior art keywords
kidney
mmhg
kpa
minutes
reconditioning
Prior art date
Application number
BR112021020429A
Other languages
English (en)
Inventor
Michael Olausson
Original Assignee
Uglk Science Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uglk Science Ab filed Critical Uglk Science Ab
Publication of BR112021020429A2 publication Critical patent/BR112021020429A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • A01N1/021Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • A01N1/021Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0236Mechanical aspects
    • A01N1/0242Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
    • A01N1/0247Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • External Artificial Organs (AREA)

Abstract

método e aparelho para recondicionar rins. método e dispositivo e fluido para recuperar um rim colhido, por exemplo, de uma carcaça de parada cardíaca, em que o rim foi exposto à isquemia quente durante 4 horas ou mais. na cirurgia em bancada, após a colheita, é injetado lys-plasminogênio no rim e, após 15 minutos, o t-pa é injetado. um fluido de circulação hiperoncótico compreendendo albumina e eletrólitos são adicionados e circulados através do rim juntamente com o referido lys-plasminogênio e t-pa, pelo qual a circulação a pressão é aumentada de 20 mmhg (2,66 kpa) para 70 mmhg (9,33 kpa) durante 30 a 75 minutos, por exemplo em passos de 5 mmhg (0,66 kpa) por 5 minutos. então, o rim é avaliado por critérios convencionais.
BR112021020429A 2019-04-12 2020-04-12 Método e aparelho para recondicionar rins BR112021020429A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE1930123 2019-04-12
PCT/SE2020/050380 WO2020209787A1 (en) 2019-04-12 2020-04-12 Method and apparatus for reconditioning kidneys

Publications (1)

Publication Number Publication Date
BR112021020429A2 true BR112021020429A2 (pt) 2021-12-14

Family

ID=72750508

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021020429A BR112021020429A2 (pt) 2019-04-12 2020-04-12 Método e aparelho para recondicionar rins

Country Status (13)

Country Link
US (1) US20220183273A1 (pt)
EP (1) EP3952644A4 (pt)
JP (1) JP2022528752A (pt)
KR (1) KR20210151202A (pt)
CN (1) CN113677201B (pt)
AU (1) AU2020270928A1 (pt)
BR (1) BR112021020429A2 (pt)
CA (1) CA3134900A1 (pt)
EA (1) EA202192438A1 (pt)
IL (1) IL287036A (pt)
MX (1) MX2021012243A (pt)
SG (1) SG11202110554YA (pt)
WO (1) WO2020209787A1 (pt)

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5520912A (en) 1993-07-02 1996-05-28 Immuno Aktiengesellschaft Prevention and treatment of ischemic events and reperfusion injury resulting therefrom using lys-plasminogen
AU8131794A (en) * 1993-11-02 1995-05-23 Emory University Composition for tissue and organ transplantation preservation
US6100082A (en) 1997-09-23 2000-08-08 Hassanein; Waleed H. Perfusion apparatus and method including chemical compositions for maintaining an organ
EP1929863B1 (en) * 1998-09-29 2016-11-09 Organ Recovery Systems, Inc. Apparatus and method for maintaining and/or restoring viability of organs
JP2004507473A (ja) * 2000-08-25 2004-03-11 オルガン リカヴァリー システムス インコーポレイテッド 血栓溶解性器官処理および修復法
AU2002214443B2 (en) * 2000-11-03 2005-12-15 Vitrolife Ab Evaluation and preservation solution
US20020197252A1 (en) * 2001-04-10 2002-12-26 Renal Tech International Selective adsorption devices and systems
EP1554347B1 (en) * 2002-10-15 2007-05-30 Agfa Graphics N.V. Polymer for heat-sensitive lithographic printing plate precursor
AU2009335398B2 (en) * 2008-12-30 2013-03-28 Endothel Pharma Aps Methods of identifying critically ill patients at increased risk of development of organ failure and compounds for the treatment hereof
WO2012128696A1 (en) * 2011-03-23 2012-09-27 Vivoline Medical Ab Apparatus for maintaining a harvested organ viable and transportable
CN204763020U (zh) * 2015-02-16 2015-11-18 杭州电子科技大学 亚常温移植器官体外智能支持系统
AU2018246007C1 (en) * 2017-03-27 2022-06-23 Cytosorbents Corporation Methods for removal of toxins from blood using an extracorporeal circuit comprised of a hollow-fiber filter module and polymer sorbent in combination
CN107156109A (zh) * 2017-05-31 2017-09-15 上海市杨浦区市东医院 一种离体器官保存系统

Also Published As

Publication number Publication date
AU2020270928A1 (en) 2021-10-21
KR20210151202A (ko) 2021-12-13
MX2021012243A (es) 2021-12-10
WO2020209787A8 (en) 2021-10-14
EA202192438A1 (ru) 2022-01-28
EP3952644A1 (en) 2022-02-16
EP3952644A4 (en) 2023-06-07
SG11202110554YA (en) 2021-10-28
US20220183273A1 (en) 2022-06-16
WO2020209787A1 (en) 2020-10-15
CN113677201B (zh) 2023-09-26
IL287036A (en) 2021-12-01
CA3134900A1 (en) 2020-10-15
JP2022528752A (ja) 2022-06-15
CN113677201A (zh) 2021-11-19

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Legal Events

Date Code Title Description
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements