BR112021006618A2 - composições e métodos para o tratamento da presbiopia - Google Patents

composições e métodos para o tratamento da presbiopia

Info

Publication number
BR112021006618A2
BR112021006618A2 BR112021006618A BR112021006618A BR112021006618A2 BR 112021006618 A2 BR112021006618 A2 BR 112021006618A2 BR 112021006618 A BR112021006618 A BR 112021006618A BR 112021006618 A BR112021006618 A BR 112021006618A BR 112021006618 A2 BR112021006618 A2 BR 112021006618A2
Authority
BR
Brazil
Prior art keywords
methods
container
presbyopia
compositions
treatment
Prior art date
Application number
BR112021006618A
Other languages
English (en)
Other versions
BR112021006618B1 (pt
Inventor
Horn Gerald
Original Assignee
Presbyopia Therapies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Presbyopia Therapies Inc filed Critical Presbyopia Therapies Inc
Publication of BR112021006618A2 publication Critical patent/BR112021006618A2/pt
Publication of BR112021006618B1 publication Critical patent/BR112021006618B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1412—Containers with closing means, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

composições e métodos para o tratamento da presbiopia. a invenção fornece composições e métodos para o tratamento da presbiopia. os métodos preferencialmente compreendem o armazenamento de uma composição de aceclidina em um recipiente tendo um espaço superior a uma temperatura de cerca de 2 a cerca de 8 graus celsius. os métodos compreendem ainda encher o recipiente sob uma camada de gás inerte e / ou encerrar o recipiente com um material anti- lixiviação ou dispor o recipiente em um segundo recipiente contendo um material anti-lixiviação.
BR112021006618-7A 2018-10-10 2019-10-08 Composições e métodos para o tratamento da presbiopia BR112021006618B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862743720P 2018-10-10 2018-10-10
US62/743,720 2018-10-10
PCT/US2019/055116 WO2020076769A1 (en) 2018-10-10 2019-10-08 Compositions and methods for the treatment of presbyopia

Publications (2)

Publication Number Publication Date
BR112021006618A2 true BR112021006618A2 (pt) 2021-07-06
BR112021006618B1 BR112021006618B1 (pt) 2022-09-27

Family

ID=70161531

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021006618-7A BR112021006618B1 (pt) 2018-10-10 2019-10-08 Composições e métodos para o tratamento da presbiopia

Country Status (12)

Country Link
US (1) US10836760B2 (pt)
EP (1) EP3863630A4 (pt)
JP (1) JP2022504746A (pt)
KR (1) KR20210076941A (pt)
CN (1) CN113518620A (pt)
AU (1) AU2019357979A1 (pt)
BR (1) BR112021006618B1 (pt)
CA (1) CA3114204A1 (pt)
MA (1) MA53873A (pt)
MX (1) MX2021004183A (pt)
SG (1) SG11202103033WA (pt)
WO (1) WO2020076769A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210338666A1 (en) * 2020-04-30 2021-11-04 Eye Therapies, Llc Brimonidine combinations and uses thereof
EP4228636A1 (en) * 2020-10-13 2023-08-23 Lenz Therapeutics, Inc. Compositions and methods for storage stable ophthalmic drugs
WO2022232205A1 (en) * 2021-04-28 2022-11-03 Lenz Therapeutics, Inc. A method of reducing brow ache
CN116459251A (zh) * 2022-01-18 2023-07-21 苏州普乐康医药科技有限公司 一种含西维美林的眼用制剂及其制备方法和应用
TW202329958A (zh) * 2022-01-25 2023-08-01 張金明 西維美林水溶液組合物和使用方法
US20230310380A1 (en) * 2022-04-05 2023-10-05 Alan Neil Glazier Methods, devices, and systems for treating lens protein aggregation diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0648118A1 (en) * 1992-07-02 1995-04-19 Telor Ophthalmic Pharmaceuticals, Inc. Methods and products for treating presbyopia
US20090297566A1 (en) * 2004-12-27 2009-12-03 Brinkman Kyle R Oxygen-impervious packaging with optional oxygen scavenger, stabilized thyroid hormone compositions and methods for storing thyroid hormone pharmaceutical compositions
US9320709B2 (en) * 2013-08-28 2016-04-26 Presbyopia Therapies Llc Storage stable compositions and methods for the treatment of refractive errors of the eye
US10307408B2 (en) * 2013-08-28 2019-06-04 Presbyopia Therapies, LLC Contact lens compositions and methods for the treatment of presbyopia
US20190038609A1 (en) * 2013-08-28 2019-02-07 Presbyopia Therapies, LLC Compositions and methods for the treatment of presbyopia

Also Published As

Publication number Publication date
MA53873A (fr) 2022-01-19
WO2020076769A1 (en) 2020-04-16
EP3863630A1 (en) 2021-08-18
BR112021006618B1 (pt) 2022-09-27
KR20210076941A (ko) 2021-06-24
AU2019357979A1 (en) 2021-04-29
CN113518620A (zh) 2021-10-19
SG11202103033WA (en) 2021-04-29
JP2022504746A (ja) 2022-01-13
MX2021004183A (es) 2021-10-26
US10836760B2 (en) 2020-11-17
EP3863630A4 (en) 2022-06-29
US20200115377A1 (en) 2020-04-16
CA3114204A1 (en) 2020-04-16

Similar Documents

Publication Publication Date Title
BR112021006618A2 (pt) composições e métodos para o tratamento da presbiopia
AR106763A1 (es) Oxadiazoles sustituidos para combatir hongos fitopatógenos
AR106679A1 (es) Oxadiazoles sustituidos para combatir hongos fitopatógenos
MY182833A (en) Apparatus and methods for labeling vials or ampoules stored at temperatures as low as -200 ?c
BR112017005316A2 (pt) propante revestido e infundido contendo agente de tratamento químico e processos de uso do mesmo
BR112017000301A2 (pt) tratamento de leucemia com inibidores de histona desacetilase
BR112019001112A2 (pt) aprimoramento da criopreservação de célula com glicolipídeos
BR112017002096A2 (pt) composições de poliuretano termoplástico e artigos e métodos dos mesmos
BR112016008644A2 (pt) Inibidor de dinamina 2 para uso no tratamento de uma miopatia centronuclear; método para identificar ou triar moléculas úteis no tratamento de uma miopatia centronuclear, de preferência, xlcnm; e composição farmacêutica
BR112015019827A2 (pt) materiais tratados de substrato por metátese e métodos de preparar e usar o mesmo
BR112018070852A2 (pt) composições de dissulfeto de selênio para uso no tratamento de disfunção das glândulas meibomianas
EA201991073A1 (ru) Ингибиторы magl
JOP20200252B1 (ar) مركبات مساعدة لعامل تمايز النمو 15 وطرق استخدامها
BR112019009137A2 (pt) composição, dispositivo, cartucho e método para gerar um meio inalável
BR112017010672A2 (pt) ?dispositivo de liberação de composições e método de tratamento cosmético?
EA201891792A1 (ru) Композиции для обработки волос
BR112017019731A2 (pt) compostos heterocíclicos tricíclicos úteis como inibidores de tnf
CL2018000558A1 (es) Compuestos útiles para inhibir ror-gamma-t
NO20180002A1 (en) Aminobenzisoxazole compounds as agonists of A7-nicotinic acetylcholine receptors
CO2017004276A2 (es) Composiciones y métodos para mejorar la movilidad o actividad o tratar la fragilidad
BR112018074755A2 (pt) composição líquida não oleosa, não aquosa, e, métodos para controle de pragas e para melhorar o crescimento das plantas.
CL2021000129A1 (es) Apirasas solubilizadas, métodos y usos
CL2021001096A1 (es) Métodos para tratar el síndrome mielodisplásico. (divisional de la solicitud no. 202000196)
BR112017016149A2 (pt) cápsula de mistura para material dentário e método para preparação de material dentário
EA201991570A1 (ru) Амидные соединения и их применение

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 08/10/2019, OBSERVADAS AS CONDICOES LEGAIS

B25D Requested change of name of applicant approved

Owner name: LENZ THERAPEUTICS, INC. (US)