BR112020008121A2 - compostos espirocíclico de alqueno como moduladores de receptor farnesoide x - Google Patents

Info

Publication number

BR112020008121A2

BR112020008121A2 BR112020008121-3A BR112020008121A BR112020008121A2 BR 112020008121 A2 BR112020008121 A2 BR 112020008121A2 BR 112020008121 A BR112020008121 A BR 112020008121A BR 112020008121 A2 BR112020008121 A2 BR 112020008121A2

Authority

BR

Brazil

Prior art keywords

independently

alkyl

mmol

heteroaryl

cyclopropyl

Prior art date

2017-11-01

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• 102100038495 Bile acid receptor Human genes 0.000 title abstract description 38
• 101000603876 Homo sapiens Bile acid receptor Proteins 0.000 title abstract description 38
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• 238000005160 1H NMR spectroscopy Methods 0.000 description 108
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• OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical class OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 74
• 235000019439 ethyl acetate Nutrition 0.000 description 74
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• CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 42
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