BR112020004760A2 - métodos e composições para tratamento de doenças pulmonares crônicas - Google Patents

métodos e composições para tratamento de doenças pulmonares crônicas Download PDF

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Publication number
BR112020004760A2
BR112020004760A2 BR112020004760-0A BR112020004760A BR112020004760A2 BR 112020004760 A2 BR112020004760 A2 BR 112020004760A2 BR 112020004760 A BR112020004760 A BR 112020004760A BR 112020004760 A2 BR112020004760 A2 BR 112020004760A2
Authority
BR
Brazil
Prior art keywords
igf
agonist
analog
months
weeks
Prior art date
Application number
BR112020004760-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Norman Barton
Alexandra Mangili
Original Assignee
Shire Human Genetic Therapies, Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Human Genetic Therapies, Inc filed Critical Shire Human Genetic Therapies, Inc
Publication of BR112020004760A2 publication Critical patent/BR112020004760A2/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1754—Insulin-like growth factor binding proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/30—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
BR112020004760-0A 2017-09-11 2018-09-11 métodos e composições para tratamento de doenças pulmonares crônicas BR112020004760A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762557113P 2017-09-11 2017-09-11
US62/557,113 2017-09-11
PCT/US2018/050427 WO2019051474A1 (en) 2017-09-11 2018-09-11 METHODS AND COMPOSITIONS FOR TREATING CHRONIC PULMONARY DISEASES

Publications (1)

Publication Number Publication Date
BR112020004760A2 true BR112020004760A2 (pt) 2020-09-15

Family

ID=63794620

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112020004760-0A BR112020004760A2 (pt) 2017-09-11 2018-09-11 métodos e composições para tratamento de doenças pulmonares crônicas

Country Status (25)

Country Link
US (3) US20190151411A1 (cg-RX-API-DMAC10.html)
EP (3) EP3681602B1 (cg-RX-API-DMAC10.html)
JP (3) JP7819893B2 (cg-RX-API-DMAC10.html)
KR (1) KR20200097679A (cg-RX-API-DMAC10.html)
CN (1) CN111432881A (cg-RX-API-DMAC10.html)
AU (2) AU2018328827B2 (cg-RX-API-DMAC10.html)
BR (1) BR112020004760A2 (cg-RX-API-DMAC10.html)
CA (1) CA3075482A1 (cg-RX-API-DMAC10.html)
CL (1) CL2020000597A1 (cg-RX-API-DMAC10.html)
CO (1) CO2020004244A2 (cg-RX-API-DMAC10.html)
DK (1) DK3681602T3 (cg-RX-API-DMAC10.html)
EA (1) EA202090705A1 (cg-RX-API-DMAC10.html)
EC (1) ECSP20055797A (cg-RX-API-DMAC10.html)
ES (1) ES3075637T3 (cg-RX-API-DMAC10.html)
IL (1) IL273174B2 (cg-RX-API-DMAC10.html)
LT (1) LT3681602T (cg-RX-API-DMAC10.html)
MX (1) MX421623B (cg-RX-API-DMAC10.html)
MY (1) MY204825A (cg-RX-API-DMAC10.html)
PE (1) PE20201166A1 (cg-RX-API-DMAC10.html)
PH (1) PH12020500489A1 (cg-RX-API-DMAC10.html)
PT (1) PT3681602T (cg-RX-API-DMAC10.html)
SG (1) SG11202002088TA (cg-RX-API-DMAC10.html)
UA (1) UA128690C2 (cg-RX-API-DMAC10.html)
WO (1) WO2019051474A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA202001568B (cg-RX-API-DMAC10.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3681602B1 (en) 2017-09-11 2026-04-15 Oak Hill Bio Limited Compositions for reducing the incidence of bpd
KR20230113287A (ko) * 2020-10-19 2023-07-28 오크 힐 바이오 리미티드 신생아에 사용하기에 적합한 조성물
CA3248280A1 (en) * 2022-05-04 2023-11-09 Oak Hill Bio Limited POLYTHERAPY FOR PREMATURE INFANTS
WO2023242440A1 (en) * 2022-06-17 2023-12-21 Oak Hill Bio Limited Treament of lungs in infants

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IL71991A (en) 1983-06-06 1994-05-30 Genentech Inc Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes
ATE90690T1 (de) 1987-04-06 1993-07-15 Celtrix Pharma Menschliche somatomedin-traeger-proteinuntereinheiten und verfahren zu ihrer herstellung.
DK131988A (da) 1988-03-11 1989-09-12 Erasmus University Igf-bindingsprotein, dna-struktur, der koder for igf-bindingsproteinet og vektor indeholdende denne dna-struktur
US5258287A (en) 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53
ATE132164T1 (de) 1988-04-12 1996-01-15 Amgen Boulder Inc Verfahren zur steigerung und zur hemmung der wirkung eines insulinähnlichen wachstumfaktors
GB8826451D0 (en) 1988-11-11 1988-12-14 Sandoz Ltd Improvements in/relating to organic compounds
IL92816A0 (en) 1988-12-22 1990-09-17 Biogrowth Inc Recombinant dna molecules,hosts,processes and human somatomedin carrier protein-like polypeptides
EP0639981A4 (en) 1992-05-08 1995-06-28 Univ Jefferson ANALOGS OF THE IGF FACTOR (01/18/94).
US5563046A (en) 1993-08-02 1996-10-08 Celtrix Pharmaceuticals, Inc. Fusion polypeptides and proteins
US5789547A (en) 1995-06-07 1998-08-04 Celtrix Pharmaceuticals, Inc. Method of producing insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) with correct folding and disulfide bonding
US5783556A (en) 1996-08-13 1998-07-21 Genentech, Inc. Formulated insulin-containing composition
EP0956041A1 (en) 1996-09-16 1999-11-17 Dalhousie University Use of igf-i for the treatment of polycystic kidney disease and related indications
US6121416A (en) 1997-04-04 2000-09-19 Genentech, Inc. Insulin-like growth factor agonist molecules
US6436897B2 (en) 1998-06-01 2002-08-20 Celtrix Pharmaceuticals, Inc. Pharmaceutical formulations for IGF/IGFBP
US20020028764A1 (en) 2000-09-04 2002-03-07 Aarhus Amt. Treatment of acute and chronic liver disease
CA2429615C (en) 2000-11-28 2016-07-12 Children's Medical Center Corporation Determination of risk and treatment of complications of prematurity
WO2004113382A1 (en) 2003-06-13 2004-12-29 Insmed, Inc. Recombinant igf expression systems
CA2899824A1 (en) 2004-12-24 2006-06-29 Insmed, Inc. Purified rhigf-i/rhigfbp-3 complexes and their method of manufacture
WO2008130315A1 (en) * 2007-04-18 2008-10-30 Premacure Ab Method and product for treatment and/or prevention of complications of prematurity
RU2558821C2 (ru) 2009-11-17 2015-08-10 Ипсен Фарма С.А.С. ЛЕКАРСТВЕННАЯ ФОРМА ДЛЯ КОМБИНАЦИИ hGH И rhIGF-1
US9168289B2 (en) 2011-02-01 2015-10-27 Mor Research Applications Ltd. Method of treatment of small for gestational age infants under two years of age
CA2897062A1 (en) 2013-01-15 2014-07-24 Teva Pharmaceutical Industries Ltd. Lyophilization process
KR20140119396A (ko) 2013-03-29 2014-10-10 삼성전자주식회사 단백질 약물의 액상 제형
EP3681602B1 (en) 2017-09-11 2026-04-15 Oak Hill Bio Limited Compositions for reducing the incidence of bpd

Also Published As

Publication number Publication date
CN111432881A (zh) 2020-07-17
AU2018328827B2 (en) 2024-07-25
IL273174B2 (en) 2024-12-01
MY204825A (en) 2024-09-18
CO2020004244A2 (es) 2020-05-29
CA3075482A1 (en) 2019-03-14
AU2024227601B2 (en) 2026-04-23
UA128690C2 (uk) 2024-10-02
MX421623B (es) 2025-03-14
JP2025114869A (ja) 2025-08-05
EP3681602B1 (en) 2026-04-15
ES3075637T3 (en) 2026-08-06
EP4663184A3 (en) 2026-03-18
US20220088132A1 (en) 2022-03-24
IL273174A (en) 2020-04-30
WO2019051474A1 (en) 2019-03-14
JP7819893B2 (ja) 2026-02-25
IL273174B1 (en) 2024-08-01
PH12020500489A1 (en) 2021-02-22
LT3681602T (lt) 2026-07-27
AU2024227601A1 (en) 2024-11-14
US20240415927A1 (en) 2024-12-19
EP4748372A2 (en) 2026-05-27
EP4748372A3 (en) 2026-08-05
KR20200097679A (ko) 2020-08-19
AU2018328827A1 (en) 2020-04-02
JP2020533344A (ja) 2020-11-19
DK3681602T3 (da) 2026-06-29
JP2023145646A (ja) 2023-10-11
US12678482B2 (en) 2026-07-14
CL2020000597A1 (es) 2020-12-04
EP3681602A1 (en) 2020-07-22
SG11202002088TA (en) 2020-04-29
ZA202001568B (en) 2023-09-27
PE20201166A1 (es) 2020-10-28
EP4663184A2 (en) 2025-12-17
EA202090705A1 (ru) 2020-06-11
ECSP20055797A (es) 2020-10-30
PT3681602T (pt) 2026-07-20
US20190151411A1 (en) 2019-05-23
MX2020002744A (es) 2020-10-01

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP)

B350 Update of information on the portal [chapter 15.35 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B25G Requested change of headquarter approved

Owner name: TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP)

B25A Requested transfer of rights approved

Owner name: OAK HILL BIO LIMITED (GB)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]