BR112020001367A2 - métodos de proteção da integridade vascular induzida por terapia de radiação direcionada - Google Patents
métodos de proteção da integridade vascular induzida por terapia de radiação direcionada Download PDFInfo
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762537049P | 2017-07-26 | 2017-07-26 | |
| US62/537,049 | 2017-07-26 | ||
| PCT/US2018/043821 WO2019023418A1 (en) | 2017-07-26 | 2018-07-26 | METHODS FOR PROTECTING VASCULAR INTEGRITY INDUCED BY TARGETED RADIOTHERAPY |
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| BR112020001367A2 true BR112020001367A2 (pt) | 2020-08-11 |
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| BR112020001367-6A BR112020001367A2 (pt) | 2017-07-26 | 2018-07-26 | métodos de proteção da integridade vascular induzida por terapia de radiação direcionada |
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| US (1) | US12251424B2 (https=) |
| EP (1) | EP3658191A1 (https=) |
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| MX2021008943A (es) * | 2019-01-25 | 2021-11-04 | Janssen Pharmaceutica Nv | Metodos para mitigar la lesion hepatica y promover la hipertrofia hepatica, la regeneracion e injerto celular en conjunto con tratamientos de radiacion y/o radiomimeticos. |
| CN113402614A (zh) * | 2021-04-22 | 2021-09-17 | 山东泉港药业有限公司 | 血小板生成素拟肽融合蛋白(fc-tmp)编码基因与应用 |
| CN119654158A (zh) * | 2022-05-20 | 2025-03-18 | 詹森药业有限公司 | 用于减轻与暴露于辐射和/或辐射或拟辐射治疗相关的肺损伤的方法 |
| WO2024095178A1 (en) | 2022-11-01 | 2024-05-10 | Janssen Pharmaceutica Nv | Thrombopoietin mimetic for use in the treatment of acute liver failure |
| WO2025002113A1 (zh) * | 2023-06-26 | 2025-01-02 | 上海济煜医药科技有限公司 | 一种人血小板生成素受体激动剂的融合蛋白 |
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| AU680422B2 (en) | 1992-06-11 | 1997-07-31 | Alkermes Controlled Therapeutics, Inc. | Erythropoietin drug delivery system |
| US5354934A (en) | 1993-02-04 | 1994-10-11 | Amgen Inc. | Pulmonary administration of erythropoietin |
| US6083913A (en) * | 1995-06-07 | 2000-07-04 | Glaxo Wellcome Inc. | Peptides and compounds that bind to a thrombopoietin receptor |
| US5869451A (en) | 1995-06-07 | 1999-02-09 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
| US7091311B2 (en) | 1996-06-07 | 2006-08-15 | Smithkline Beecham Corporation | Peptides and compounds that bind to a receptor |
| US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
| ES2781475T3 (es) | 2002-09-18 | 2020-09-02 | Janssen Pharmaceuticals Inc | Métodos para aumentar la producción de células madre hematopoyéticas y plaquetas |
| US7723295B2 (en) | 2003-08-28 | 2010-05-25 | Ortho-Mcneil Pharmaceutical, Inc. | Peptides and compounds that bind to a receptor |
| SG131110A1 (en) | 2003-08-28 | 2007-04-26 | Ortho Mcneil Pharm Inc | Peptides and compounds that bind to thrombopoietin receptors |
| US20060210542A1 (en) | 2004-08-16 | 2006-09-21 | Yurkow Edward J | Use of TPO mimetic compounds and pharmaceutical compositions in the treatment of anemia |
| US7615533B2 (en) | 2004-08-16 | 2009-11-10 | Janssen Pharmaceutica N.V. | TPO peptide compounds for treatment of anemia |
| EP1986677A2 (en) * | 2006-01-25 | 2008-11-05 | Amgen Inc. | Thrombopoietic compounds |
| DK1984014T3 (da) | 2006-02-14 | 2014-09-15 | Janssen Pharmaceutica Nv | Anvendelse af tpo-peptidforbindelser og farmaceutiske sammensætninger ved behandlingen af anæmi |
| CN100391474C (zh) * | 2006-06-13 | 2008-06-04 | 卢建军 | 用于治疗血小板减少的注射用药物 |
| CA2670345A1 (en) | 2006-12-01 | 2008-06-12 | Stategics, Inc. | Thrombopoietin mimetics |
| US8383124B2 (en) | 2008-03-12 | 2013-02-26 | Children's Hospital Medical Center | Mobilization of hematopoietic stem cells |
| ES2729622T3 (es) | 2008-06-03 | 2019-11-05 | Janssen Pharmaceutica Nv | Péptido mimético de TPO para prevenir el desorden hematológico asociado al tratamiento contra el cáncer |
| JP2012518408A (ja) | 2009-02-24 | 2012-08-16 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | 治療用ｔｐｏ／ｅｐｏ模倣ペプチドを含む抗体 |
| JP2012250880A (ja) | 2011-06-03 | 2012-12-20 | Semiconductor Energy Lab Co Ltd | グラフェン、蓄電装置および電気機器 |
| US20140047572A1 (en) | 2012-08-13 | 2014-02-13 | University Of Rochester | Thrombopoietin mimetics for the treatment of radiation or chemical induced bone marrow injury |
| US20140051631A1 (en) | 2012-08-17 | 2014-02-20 | Francoise Porteu | Pharmaceutical composition comprising tpo or an agonist of the tpo receptor |
| JP6150374B2 (ja) | 2012-11-15 | 2017-06-21 | 国立大学法人弘前大学 | 放射線被ばく治療剤及び放射線被ばく治療方法 |
| WO2020154637A1 (en) | 2019-01-25 | 2020-07-30 | Janssen Pharmaceutica Nv | Methods of enhancing protection against organ and vascular injury, hematopoietic recovery and survival in response to total body radiation/chemical exposure |
| MX2021008943A (es) | 2019-01-25 | 2021-11-04 | Janssen Pharmaceutica Nv | Metodos para mitigar la lesion hepatica y promover la hipertrofia hepatica, la regeneracion e injerto celular en conjunto con tratamientos de radiacion y/o radiomimeticos. |
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| WO2019023418A1 (en) | 2019-01-31 |
| AU2018306329B2 (en) | 2024-09-19 |
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| CN111432845B (zh) | 2024-02-06 |
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| US12251424B2 (en) | 2025-03-18 |
| KR102688415B1 (ko) | 2024-07-24 |
| CN111432845A (zh) | 2020-07-17 |
| JP2020528903A (ja) | 2020-10-01 |
| US20200164039A1 (en) | 2020-05-28 |
| EP3658191A1 (en) | 2020-06-03 |
| AU2018306329A1 (en) | 2020-02-13 |
| PH12020500166A1 (en) | 2020-09-14 |
| AU2018306329B8 (en) | 2025-02-20 |
| IL272213A (en) | 2020-03-31 |
| CA3070442A1 (en) | 2019-01-31 |
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