BR112019024483A2 - Método de tratamento de lesão cerebral traumática - Google Patents

Método de tratamento de lesão cerebral traumática Download PDF

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Publication number
BR112019024483A2
BR112019024483A2 BR112019024483-2A BR112019024483A BR112019024483A2 BR 112019024483 A2 BR112019024483 A2 BR 112019024483A2 BR 112019024483 A BR112019024483 A BR 112019024483A BR 112019024483 A2 BR112019024483 A2 BR 112019024483A2
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BR
Brazil
Prior art keywords
cerebral injury
treating traumatic
traumatic cerebral
treating
patient
Prior art date
Application number
BR112019024483-2A
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English (en)
Inventor
Chan Phillip
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Cytosorbents Corporation
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Filing date
Publication date
Application filed by Cytosorbents Corporation filed Critical Cytosorbents Corporation
Publication of BR112019024483A2 publication Critical patent/BR112019024483A2/pt

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/717—Celluloses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/362—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits changing physical properties of target cells by binding them to added particles to facilitate their subsequent separation from other cells, e.g. immunoaffinity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
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    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3687—Chemical treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3692—Washing or rinsing blood or blood constituents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
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    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/24—Naturally occurring macromolecular compounds, e.g. humic acids or their derivatives
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J20/26—Synthetic macromolecular compounds
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J20/28069—Pore volume, e.g. total pore volume, mesopore volume, micropore volume
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    • B01J20/28069—Pore volume, e.g. total pore volume, mesopore volume, micropore volume
    • B01J20/28076—Pore volume, e.g. total pore volume, mesopore volume, micropore volume being more than 1.0 ml/g
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
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    • B01J20/3268—Macromolecular compounds
    • B01J20/3276—Copolymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Nanotechnology (AREA)
  • Immunology (AREA)
  • Thermal Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

a presente invenção se refere a métodos de tratamento de um paciente que sofre de uma lesão cerebral traumática (lct), compreendendo colocar em contato o sangue do dito paciente com um sorvente para um mediador inflamatório e kits para a realização dos ditos tratamentos.
BR112019024483-2A 2017-05-23 2018-05-21 Método de tratamento de lesão cerebral traumática BR112019024483A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762509790P 2017-05-23 2017-05-23
US62/509,790 2017-05-23
PCT/US2018/033661 WO2018217629A1 (en) 2017-05-23 2018-05-21 Method of treating traumatic brain injury

Publications (1)

Publication Number Publication Date
BR112019024483A2 true BR112019024483A2 (pt) 2020-06-16

Family

ID=64395868

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019024483-2A BR112019024483A2 (pt) 2017-05-23 2018-05-21 Método de tratamento de lesão cerebral traumática

Country Status (10)

Country Link
US (1) US20200086032A1 (pt)
EP (1) EP3630325A4 (pt)
JP (2) JP2020521539A (pt)
KR (1) KR20200010418A (pt)
CN (1) CN110662590B (pt)
AU (1) AU2018273348A1 (pt)
BR (1) BR112019024483A2 (pt)
CA (1) CA3063468A1 (pt)
MX (1) MX2019014058A (pt)
WO (1) WO2018217629A1 (pt)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4265768A (en) * 1979-12-26 1981-05-05 Rohm And Haas Company Ion exchange material prepared from partially pyrolyzed macroporous polymer particles
US20020197250A1 (en) * 2001-04-10 2002-12-26 Renal Tech International Biocompatible devices, systems, and methods for reducing levels of pro-inflammatory or anti-inflammatory stimulators or mediators in the blood
IT1319785B1 (it) * 2000-01-12 2003-11-03 Gambro Dasco Spa Metodo di svuotamento di un circuito ematico in una macchina didialisi e circuito ematico per l'attuazione del metodo.
US8535258B2 (en) * 2000-03-24 2013-09-17 Immunocept, L.L.C. Hemofiltration methods for treatment of diseases in a mammal
US9604196B2 (en) * 2006-11-20 2017-03-28 Cytosorbent, Inc. Size-selective hemocompatible polymer system
US20100222421A1 (en) * 2009-02-27 2010-09-02 National Defense Medical Center Usage of Baicalein in the Preparation of a Pharmaceutical Composition for the Treatment of Traumatic Brain Injury
CA2795177C (en) * 2010-04-01 2018-07-03 Cytosorbents Corporation Method of treating inflammation
US10064406B2 (en) * 2011-01-06 2018-09-04 Cytosorbents Corporation Polymeric sorbent for removal of impurities from whole blood and blood products
US10426158B2 (en) * 2011-08-12 2019-10-01 Cytosorbents Corporation Polymeric sorbent for removal of impurities from whole blood and blood products
US20150335576A1 (en) * 2012-06-29 2015-11-26 Cytosorbents Corporation Methods of using polymers
CN106457205B (zh) * 2014-07-22 2020-09-22 旭化成医疗株式会社 去除组蛋白的吸附材料和生物来源液体净化设备
RU2742768C2 (ru) * 2015-10-22 2021-02-10 Сайтосорбентс Корпорейшн Применение многофункционального гемосовместимого пористого полимерно гранулированного сорбента для удаления гемоглобина, калия, цитокинов, биоактивных липидов и иммуноглобулинов из биологических жидкостей

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Publication number Publication date
CA3063468A1 (en) 2018-11-29
CN110662590A (zh) 2020-01-07
WO2018217629A1 (en) 2018-11-29
KR20200010418A (ko) 2020-01-30
MX2019014058A (es) 2020-07-28
JP2020521539A (ja) 2020-07-27
AU2018273348A1 (en) 2019-11-21
JP2023078459A (ja) 2023-06-06
CN110662590B (zh) 2022-12-23
EP3630325A4 (en) 2021-02-17
EP3630325A1 (en) 2020-04-08
US20200086032A1 (en) 2020-03-19

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