BR112019006336A2 - beta-caseínas e a microbiota intestinal - Google Patents
beta-caseínas e a microbiota intestinalInfo
- Publication number
- BR112019006336A2 BR112019006336A2 BR112019006336A BR112019006336A BR112019006336A2 BR 112019006336 A2 BR112019006336 A2 BR 112019006336A2 BR 112019006336 A BR112019006336 A BR 112019006336A BR 112019006336 A BR112019006336 A BR 112019006336A BR 112019006336 A2 BR112019006336 A2 BR 112019006336A2
- Authority
- BR
- Brazil
- Prior art keywords
- beta
- casein
- caseins
- gut microbiota
- proline
- Prior art date
Links
- 102000011632 Caseins Human genes 0.000 title abstract 5
- 108010076119 Caseins Proteins 0.000 title abstract 5
- 235000021247 β-casein Nutrition 0.000 title abstract 5
- 244000005709 gut microbiome Species 0.000 title abstract 2
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 125000001500 prolyl group Chemical group [H]N1C([H])(C(=O)[*])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C13/00—Cream; Cream preparations; Making thereof
- A23C13/12—Cream preparations
- A23C13/14—Cream preparations containing milk products or non-fat milk components
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C15/00—Butter; Butter preparations; Making thereof
- A23C15/12—Butter preparations
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C19/00—Cheese; Cheese preparations; Making thereof
- A23C19/06—Treating cheese curd after whey separation; Products obtained thereby
- A23C19/09—Other cheese preparations; Mixtures of cheese with other foodstuffs
- A23C19/0917—Addition, to cheese or curd, of whey, whey components, substances recovered from separated whey, isolated or concentrated proteins from milk
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/13—Fermented milk preparations; Treatment using microorganisms or enzymes using additives
- A23C9/1307—Milk products or derivatives; Fruit or vegetable juices; Sugars, sugar alcohols, sweeteners; Oligosaccharides; Organic acids or salts thereof or acidifying agents; Flavours, dyes or pigments; Inert or aerosol gases; Carbonation methods
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/15—Reconstituted or recombined milk products containing neither non-milk fat nor non-milk proteins
- A23C9/1512—Reconstituted or recombined milk products containing neither non-milk fat nor non-milk proteins containing isolated milk or whey proteins, caseinates or cheese; Enrichment of milk products with milk proteins in isolated or concentrated form, e.g. ultrafiltration retentate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/20—Milk; Whey; Colostrum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
- A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
- A23J1/202—Casein or caseinates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
- A23V2200/32—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the digestive tract
- A23V2200/3202—Prebiotics, ingredients fermented in the gastrointestinal tract by beneficial microflora
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/54—Proteins
- A23V2250/542—Animal Protein
- A23V2250/5424—Dairy protein
- A23V2250/54246—Casein
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Dairy Products (AREA)
- Confectionery (AREA)
Abstract
a melhora do equilíbrio da microbiota intestinal benéfica de um animal provendo uma composição contendo beta-caseína, em que pelo menos 75% em peso da beta-caseína é uma variante da beta-caseína que tem uma prolina na posição 67 da sequência de aminoácidos da beta-caseína.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/NZ2016/050161 WO2018063008A1 (en) | 2016-09-30 | 2016-09-30 | Beta-caseins and gut microbiota |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112019006336A2 true BR112019006336A2 (pt) | 2019-06-25 |
BR112019006336B1 BR112019006336B1 (pt) | 2021-09-21 |
Family
ID=61759958
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112019006336-6A BR112019006336B1 (pt) | 2016-09-30 | 2016-09-30 | Beta-caseínas e a microbiota intestinal |
Country Status (11)
Country | Link |
---|---|
US (1) | US11925197B2 (pt) |
JP (1) | JP6873234B2 (pt) |
KR (2) | KR20220040497A (pt) |
AU (1) | AU2016424981B2 (pt) |
BR (1) | BR112019006336B1 (pt) |
CA (1) | CA3036494C (pt) |
MX (1) | MX2019003636A (pt) |
MY (1) | MY186302A (pt) |
PH (1) | PH12019550035A1 (pt) |
RU (1) | RU2769989C2 (pt) |
WO (1) | WO2018063008A1 (pt) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN118201501A (zh) * | 2021-12-03 | 2024-06-14 | N·V·努特里奇亚 | 用于改善婴儿微生物群的营养组合物 |
WO2024056784A1 (en) | 2022-09-14 | 2024-03-21 | N.V. Nutricia | Nutritional composition |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU691362B2 (en) | 1994-11-04 | 1998-05-14 | New Zealand Dairy Board | Method of selecting non-diabetogenic milk or milk products and milk or milk products so selected |
WO1996036239A1 (en) | 1995-05-16 | 1996-11-21 | Corran Norman Stuart Mclachlan | Food product and process |
EP1196047A4 (en) * | 1999-06-29 | 2004-12-22 | New Zealand Milk Inst Ltd | MILK-BASED PROPHYLACTIC FOOD SUPPLEMENTS |
AU9037401A (en) | 2000-09-08 | 2002-03-22 | New Zealand Dairy Board | Milk containing beta-casein with proline at position 67 does not aggravate neurological disorders |
US20060280802A1 (en) | 2002-10-04 | 2006-12-14 | Campbell Julie H | Therapeutic uses of beta-casein a2 and dietary supplement containing beta-casein a2 |
CN102123715B (zh) * | 2008-06-13 | 2014-12-17 | N.V.努特里奇亚 | 刺激免疫系统的营养物 |
JP6234227B2 (ja) * | 2011-11-30 | 2017-11-22 | 株式会社明治 | 腸内菌叢改善用栄養組成物 |
CA2913890A1 (en) * | 2013-05-31 | 2014-12-04 | The A2 Milk Company Limited | Beta-casein a2 and prevention of inflammation of the bowel |
CN105431156A (zh) * | 2013-07-12 | 2016-03-23 | 艾尔牛奶有限公司 | β-酪蛋白A2和减轻或预防乳糖不耐受症状 |
KR102626825B1 (ko) * | 2013-08-23 | 2024-01-17 | 디 에이2 밀크 컴퍼니 리미티드 | 베타-카세인 a2 및 혈중 글루코스 수준 |
CN103918792A (zh) | 2014-04-10 | 2014-07-16 | 陕西科技大学 | 一种木糖醇益生菌羊奶片及其制备方法 |
EP3297643A4 (en) * | 2015-05-22 | 2019-02-06 | The A2 Milk Company Limited | BETA-CASEIN-A2 AND ANTIOXIDATIVE CAPACITY |
-
2016
- 2016-09-30 AU AU2016424981A patent/AU2016424981B2/en active Active
- 2016-09-30 US US16/333,939 patent/US11925197B2/en active Active
- 2016-09-30 KR KR1020227008438A patent/KR20220040497A/ko not_active Application Discontinuation
- 2016-09-30 RU RU2019107600A patent/RU2769989C2/ru active
- 2016-09-30 BR BR112019006336-6A patent/BR112019006336B1/pt active IP Right Grant
- 2016-09-30 MX MX2019003636A patent/MX2019003636A/es unknown
- 2016-09-30 WO PCT/NZ2016/050161 patent/WO2018063008A1/en active Application Filing
- 2016-09-30 KR KR1020197009048A patent/KR102431753B1/ko active IP Right Grant
- 2016-09-30 JP JP2019517409A patent/JP6873234B2/ja active Active
- 2016-09-30 CA CA3036494A patent/CA3036494C/en active Active
- 2016-09-30 MY MYPI2019001532A patent/MY186302A/en unknown
-
2019
- 2019-03-08 PH PH12019550035A patent/PH12019550035A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
US20200008458A1 (en) | 2020-01-09 |
RU2019107600A3 (pt) | 2020-10-30 |
PH12019550035A1 (en) | 2019-07-24 |
RU2019107600A (ru) | 2020-10-30 |
CA3036494C (en) | 2022-10-18 |
US11925197B2 (en) | 2024-03-12 |
WO2018063008A1 (en) | 2018-04-05 |
RU2769989C2 (ru) | 2022-04-12 |
KR20190063463A (ko) | 2019-06-07 |
BR112019006336B1 (pt) | 2021-09-21 |
AU2016424981A1 (en) | 2019-04-11 |
AU2016424981B2 (en) | 2021-11-04 |
KR20220040497A (ko) | 2022-03-30 |
CA3036494A1 (en) | 2018-04-05 |
KR102431753B1 (ko) | 2022-08-11 |
MY186302A (en) | 2021-07-07 |
JP6873234B2 (ja) | 2021-05-19 |
JP2019532645A (ja) | 2019-11-14 |
MX2019003636A (es) | 2019-06-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/09/2016, OBSERVADAS AS CONDICOES LEGAIS. |