BR112019002689A2 - terapia com rapamicina tópica - Google Patents
terapia com rapamicina tópicaInfo
- Publication number
- BR112019002689A2 BR112019002689A2 BR112019002689A BR112019002689A BR112019002689A2 BR 112019002689 A2 BR112019002689 A2 BR 112019002689A2 BR 112019002689 A BR112019002689 A BR 112019002689A BR 112019002689 A BR112019002689 A BR 112019002689A BR 112019002689 A2 BR112019002689 A2 BR 112019002689A2
- Authority
- BR
- Brazil
- Prior art keywords
- rapamycin
- conditions
- topical rapamycin
- rapamycin therapy
- therapy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662372940P | 2016-08-10 | 2016-08-10 | |
PCT/US2017/046320 WO2018031789A1 (en) | 2016-08-10 | 2017-08-10 | Topical rapamycin therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112019002689A2 true BR112019002689A2 (pt) | 2019-05-14 |
Family
ID=59684091
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112019002689A BR112019002689A2 (pt) | 2016-08-10 | 2017-08-10 | terapia com rapamicina tópica |
Country Status (11)
Country | Link |
---|---|
US (1) | US20190167649A1 (pt) |
EP (1) | EP3496712A1 (pt) |
JP (1) | JP2019527711A (pt) |
KR (1) | KR20190039220A (pt) |
CN (1) | CN109689053A (pt) |
AU (1) | AU2017311491A1 (pt) |
BR (1) | BR112019002689A2 (pt) |
CA (1) | CA3032473A1 (pt) |
MX (1) | MX2019001670A (pt) |
RU (1) | RU2019106483A (pt) |
WO (1) | WO2018031789A1 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL302385B1 (en) | 2017-01-06 | 2024-02-01 | Palvella Therapeutics Inc | Non-aqueous preparations of mTOR inhibitors and methods of use |
US20210177810A1 (en) * | 2018-02-06 | 2021-06-17 | Georgetown University | TOPICAL mTOR INHIBITORS FOR CUTANEOUS PROLIFERATIVE AND VASCULAR CONDITIONS |
EP3817743A4 (en) | 2018-07-02 | 2022-07-06 | Palvella Therapeutics, Inc. | ANHYDROUS COMPOSITIONS OF MTOR INHIBITORS AND METHODS OF USE |
BR112021003497A2 (pt) * | 2018-08-30 | 2021-05-18 | Chemistryrx. | composições contendo sirolimo |
CN109431997B (zh) * | 2018-12-20 | 2021-06-04 | 武汉科福新药有限责任公司 | 一种雷帕霉素局部注射制剂及其制备方法 |
KR20210130769A (ko) | 2019-02-20 | 2021-11-01 | 에이아이 테라퓨틱스, 인코포레이티드 | 국소 라파마이신 제형 및 안면 혈관섬유종 및 다른 피부 장애에서의 이의 용도 |
US20220142990A1 (en) * | 2019-02-27 | 2022-05-12 | Osaka University | External preparation for treating a vascular anomaly |
EP4094761A4 (en) | 2020-01-24 | 2023-12-27 | Nobelpharma Co., Ltd. | EXTERNAL PREPARATION CONTAINING RAPAMYCIN |
AU2020277132B1 (en) * | 2020-11-24 | 2021-11-04 | Aft Pharmaceuticals Limited | A Rapamycin Composition |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9606452D0 (en) | 1996-03-27 | 1996-06-05 | Sandoz Ltd | Organic compounds |
US6258823B1 (en) | 1996-07-12 | 2001-07-10 | Ariad Pharmaceuticals, Inc. | Materials and method for treating or preventing pathogenic fungal infection |
GB9723669D0 (en) | 1997-11-07 | 1998-01-07 | Univ Aberdeen | Skin penetration enhancing components |
RU2005106855A (ru) | 2002-08-12 | 2005-10-10 | Дзе Риджентс оф дзе Юниверсити оф Мичиган (US) | Диагностика и лечение заболеваний, вызываемых дефектами каскада реакций, обусловливающих туберозный склероз |
AU2006218918A1 (en) | 2005-03-02 | 2006-09-08 | Wyeth | Purification of rapamycin |
US20100305150A1 (en) | 2006-02-02 | 2010-12-02 | Novartis Ag | Tuberous sclerosis treatment |
US20120022095A1 (en) | 2010-06-24 | 2012-01-26 | Teng Joyce M C | Topical rapamycin for treatment of facial angiofibromas in tuberous sclerosis |
WO2012142145A1 (en) * | 2011-04-12 | 2012-10-18 | Dow Pharmaceutical Sciences | Methods of treating skin conditions exhibiting telangiectasia |
ES2797376T3 (es) * | 2013-01-24 | 2020-12-02 | Palvella Therapeutics Inc | Composiciones para la administración transdérmica de inhibidores de mTOR |
HUP1400075A2 (hu) * | 2014-02-14 | 2015-08-28 | Druggability Technologies Ip Holdco Jersey Ltd | Sirolimus és származékainak komplexei, elõállítása és gyógyszerészeti kompozíciói |
CN115645534A (zh) * | 2015-09-24 | 2023-01-31 | 德雷克塞尔大学 | 治疗或预防皮肤障碍的新型组合物和方法 |
CN105663027B (zh) * | 2016-04-01 | 2018-12-18 | 中国人民解放军广州军区武汉总医院 | 西罗莫司外用制剂、其制备方法及用途 |
-
2017
- 2017-08-10 RU RU2019106483A patent/RU2019106483A/ru unknown
- 2017-08-10 WO PCT/US2017/046320 patent/WO2018031789A1/en unknown
- 2017-08-10 BR BR112019002689A patent/BR112019002689A2/pt not_active IP Right Cessation
- 2017-08-10 CA CA3032473A patent/CA3032473A1/en not_active Abandoned
- 2017-08-10 KR KR1020197006896A patent/KR20190039220A/ko not_active Application Discontinuation
- 2017-08-10 AU AU2017311491A patent/AU2017311491A1/en not_active Abandoned
- 2017-08-10 MX MX2019001670A patent/MX2019001670A/es unknown
- 2017-08-10 EP EP17755383.1A patent/EP3496712A1/en not_active Withdrawn
- 2017-08-10 CN CN201780049324.6A patent/CN109689053A/zh active Pending
- 2017-08-10 JP JP2019506721A patent/JP2019527711A/ja active Pending
- 2017-08-10 US US16/324,274 patent/US20190167649A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
KR20190039220A (ko) | 2019-04-10 |
EP3496712A1 (en) | 2019-06-19 |
RU2019106483A3 (pt) | 2020-12-04 |
JP2019527711A (ja) | 2019-10-03 |
RU2019106483A (ru) | 2020-09-11 |
AU2017311491A1 (en) | 2019-02-07 |
CN109689053A (zh) | 2019-04-26 |
WO2018031789A1 (en) | 2018-02-15 |
CA3032473A1 (en) | 2018-02-15 |
MX2019001670A (es) | 2019-07-04 |
US20190167649A1 (en) | 2019-06-06 |
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Legal Events
Date | Code | Title | Description |
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI N? 10196/2001, QUE MODIFICOU A LEI N? 9279/96, A CONCESS?O DA PATENTE EST? CONDICIONADA ? ANU?NCIA PR?VIA DA ANVISA. CONSIDERANDO A APROVA??O DOS TERMOS DO PARECER N? 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL N? 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVID?NCIAS CAB?VEIS. |
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B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2735 DE 06-06-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |