BR112018067563A8 - sistemas e métodos para a produção de hipericina sintética. - Google Patents
sistemas e métodos para a produção de hipericina sintética.Info
- Publication number
- BR112018067563A8 BR112018067563A8 BR112018067563A BR112018067563A BR112018067563A8 BR 112018067563 A8 BR112018067563 A8 BR 112018067563A8 BR 112018067563 A BR112018067563 A BR 112018067563A BR 112018067563 A BR112018067563 A BR 112018067563A BR 112018067563 A8 BR112018067563 A8 BR 112018067563A8
- Authority
- BR
- Brazil
- Prior art keywords
- production
- methods
- systems
- synthetic hypericin
- hypericin
- Prior art date
Links
- BTXNYTINYBABQR-UHFFFAOYSA-N hypericin Chemical compound C12=C(O)C=C(O)C(C(C=3C(O)=CC(C)=C4C=33)=O)=C2C3=C2C3=C4C(C)=CC(O)=C3C(=O)C3=C(O)C=C(O)C1=C32 BTXNYTINYBABQR-UHFFFAOYSA-N 0.000 title abstract 2
- 229940005608 hypericin Drugs 0.000 title abstract 2
- PHOKTTKFQUYZPI-UHFFFAOYSA-N hypericin Natural products Cc1cc(O)c2c3C(=O)C(=Cc4c(O)c5c(O)cc(O)c6c7C(=O)C(=Cc8c(C)c1c2c(c78)c(c34)c56)O)O PHOKTTKFQUYZPI-UHFFFAOYSA-N 0.000 title abstract 2
- SSKVDVBQSWQEGJ-UHFFFAOYSA-N pseudohypericin Natural products C12=C(O)C=C(O)C(C(C=3C(O)=CC(O)=C4C=33)=O)=C2C3=C2C3=C4C(C)=CC(O)=C3C(=O)C3=C(O)C=C(O)C1=C32 SSKVDVBQSWQEGJ-UHFFFAOYSA-N 0.000 title abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
- C07C46/10—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
- C07C50/36—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having four or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/54—Ortho- or ortho- and peri-condensed systems containing more than five condensed rings
Abstract
a presente invenção se refere-se a sistemas e métodos aprimorados para a produção de hipericina sintética em alto volume e alta pureza.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2016/020189 WO2017151111A1 (en) | 2016-03-01 | 2016-03-01 | Systems and methods for producing synthetic hypericin |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112018067563A2 BR112018067563A2 (pt) | 2019-01-08 |
BR112018067563A8 true BR112018067563A8 (pt) | 2021-03-30 |
Family
ID=59744267
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018067563A BR112018067563A8 (pt) | 2016-03-01 | 2016-03-01 | sistemas e métodos para a produção de hipericina sintética. |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP3423428A4 (pt) |
JP (1) | JP6890616B2 (pt) |
KR (2) | KR20230148401A (pt) |
CN (1) | CN109071397A (pt) |
AU (2) | AU2016396033B2 (pt) |
BR (1) | BR112018067563A8 (pt) |
CA (1) | CA3016618C (pt) |
IL (2) | IL281618B1 (pt) |
RU (1) | RU2719582C1 (pt) |
SG (1) | SG11201807454YA (pt) |
WO (1) | WO2017151111A1 (pt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR3111640B1 (fr) | 2020-06-22 | 2022-07-22 | Total Marketing Services | Composition aqueuse pour la lubrification des systèmes mécaniques |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL93682A (en) * | 1989-03-16 | 1996-06-18 | Yeda Res & Dev | Polycyclic compounds with antigypical activity are used in the manufacture of medicines and pharmaceutical preparations containing them |
IL92315A (en) * | 1989-11-15 | 1996-12-05 | Yeda Res & Dev | Preparation of Hypericin from Amodin Enron |
US5543016A (en) * | 1991-07-12 | 1996-08-06 | Inrad | Photoconversion of steroids in microreactors |
IL104693A0 (en) * | 1992-02-14 | 1993-06-10 | Yeda Res & Dev | Hypericin derivatives and pharmaceutical compositions comprising them |
US6576784B1 (en) * | 1993-05-27 | 2003-06-10 | Yeda Research And Development Co. Ltd. | Antiviral agents |
IL121440A0 (en) | 1997-07-31 | 1998-01-04 | Yeda Res & Dev | The use of 1,3,4,6-tetrahydroxy-helianthrone and its derivatives in photodynamic therapy and certain such novel derivatives |
KR20010071822A (ko) * | 1998-07-09 | 2001-07-31 | 브루스, 제임스 에이취 | 특이적 티-형 칼슘 경로 차단제로서의 하이퍼리신 및하이퍼리쿰 추출물 및 이것의 특이적 티-형 칼슘 통로차단제로서의 용도 |
DE60125048T2 (de) | 2000-01-31 | 2007-07-12 | New York University | Polycyclische dianthrachinone als antikrebsmittel und antiangiogenesemittel |
JP5349930B2 (ja) * | 2008-12-04 | 2013-11-20 | 三井造船株式会社 | トルエン類の酸化処理方法 |
US8629302B2 (en) * | 2009-09-15 | 2014-01-14 | Alfonso J. Tobia | Methods for preparing hypericin |
CN102180782B (zh) * | 2011-03-23 | 2013-04-10 | 中国农业科学院兰州畜牧与兽药研究所 | 一种金丝桃素的合成方法 |
CN103274920B (zh) * | 2013-06-14 | 2014-12-17 | 西北农林科技大学 | 一种单色光引发高效合成金丝桃素的方法 |
JP2015164980A (ja) * | 2014-03-03 | 2015-09-17 | 川崎化成工業株式会社 | 光反応性組成物 |
CN104193610B (zh) * | 2014-08-05 | 2015-12-02 | 中南大学 | 金丝桃素的合成方法 |
-
2016
- 2016-03-01 WO PCT/US2016/020189 patent/WO2017151111A1/en active Application Filing
- 2016-03-01 JP JP2018566185A patent/JP6890616B2/ja active Active
- 2016-03-01 BR BR112018067563A patent/BR112018067563A8/pt not_active Application Discontinuation
- 2016-03-01 EP EP16892859.6A patent/EP3423428A4/en active Pending
- 2016-03-01 RU RU2018133949A patent/RU2719582C1/ru active
- 2016-03-01 IL IL281618A patent/IL281618B1/en unknown
- 2016-03-01 CA CA3016618A patent/CA3016618C/en active Active
- 2016-03-01 KR KR1020237035647A patent/KR20230148401A/ko not_active Application Discontinuation
- 2016-03-01 CN CN201680083494.1A patent/CN109071397A/zh active Pending
- 2016-03-01 KR KR1020187028336A patent/KR102592878B1/ko active IP Right Grant
- 2016-03-01 SG SG11201807454YA patent/SG11201807454YA/en unknown
- 2016-03-01 AU AU2016396033A patent/AU2016396033B2/en active Active
-
2018
- 2018-09-02 IL IL261531A patent/IL261531B/en active IP Right Grant
-
2021
- 2021-06-07 AU AU2021203704A patent/AU2021203704B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
IL281618A (en) | 2021-05-31 |
KR102592878B1 (ko) | 2023-10-20 |
JP2019507192A (ja) | 2019-03-14 |
AU2016396033A1 (en) | 2018-10-18 |
CA3016618A1 (en) | 2017-09-08 |
AU2021203704A1 (en) | 2021-07-08 |
AU2021203704B2 (en) | 2023-02-16 |
BR112018067563A2 (pt) | 2019-01-08 |
KR20230148401A (ko) | 2023-10-24 |
RU2719582C1 (ru) | 2020-04-21 |
WO2017151111A1 (en) | 2017-09-08 |
EP3423428A4 (en) | 2019-12-11 |
IL281618B1 (en) | 2024-01-01 |
KR20190004260A (ko) | 2019-01-11 |
NZ746762A (en) | 2023-09-29 |
CA3016618C (en) | 2023-12-19 |
EP3423428A1 (en) | 2019-01-09 |
AU2016396033B2 (en) | 2021-07-08 |
IL261531A (en) | 2018-10-31 |
JP6890616B2 (ja) | 2021-06-18 |
SG11201807454YA (en) | 2018-09-27 |
CN109071397A (zh) | 2018-12-21 |
IL261531B (en) | 2021-04-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B12B | Appeal against refusal [chapter 12.2 patent gazette] |