BR112018013588A2 - derivados de di-hidrochacolnas que influenciam estados inflamatórios - Google Patents

derivados de di-hidrochacolnas que influenciam estados inflamatórios

Info

Publication number
BR112018013588A2
BR112018013588A2 BR112018013588A BR112018013588A BR112018013588A2 BR 112018013588 A2 BR112018013588 A2 BR 112018013588A2 BR 112018013588 A BR112018013588 A BR 112018013588A BR 112018013588 A BR112018013588 A BR 112018013588A BR 112018013588 A2 BR112018013588 A2 BR 112018013588A2
Authority
BR
Brazil
Prior art keywords
dihydrochacol
derivatives
inflammatory states
influence inflammatory
influence
Prior art date
Application number
BR112018013588A
Other languages
English (en)
Inventor
Ley Jakob
Hans Joachim
Schuller Katharina
Somoza Veronika
Original Assignee
Symrise Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symrise Ag filed Critical Symrise Ag
Publication of BR112018013588A2 publication Critical patent/BR112018013588A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/121—Ketones acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

a presente invenção refere-se à área de composições farmacêuticas e cosméticas e refere-se a compostos, novas misturas e preparações compreendendo certos compostos de fórmula (i) que apresentam propriedades anti-inflamatórias.
BR112018013588A 2016-04-28 2016-04-28 derivados de di-hidrochacolnas que influenciam estados inflamatórios BR112018013588A2 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2016/059566 WO2017186298A1 (en) 2016-04-28 2016-04-28 Dihydrochalcone derivatives influencing inflammatory states

Publications (1)

Publication Number Publication Date
BR112018013588A2 true BR112018013588A2 (pt) 2019-01-08

Family

ID=56068832

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018013588A BR112018013588A2 (pt) 2016-04-28 2016-04-28 derivados de di-hidrochacolnas que influenciam estados inflamatórios

Country Status (11)

Country Link
US (1) US11759435B2 (pt)
EP (1) EP3448373B1 (pt)
JP (1) JP6802849B2 (pt)
KR (1) KR20190021194A (pt)
CN (1) CN109310649B (pt)
AU (1) AU2016405258A1 (pt)
BR (1) BR112018013588A2 (pt)
ES (1) ES2911338T3 (pt)
PH (1) PH12018501804A1 (pt)
RU (1) RU2018141595A (pt)
WO (1) WO2017186298A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114404649B (zh) * 2022-01-24 2022-06-24 西安交通大学 一种具有pH/葡萄糖双响应性释放二甲双胍的水凝胶及制备方法和应用

Family Cites Families (42)

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US3159585A (en) 1961-04-12 1964-12-01 Nat Starch Chem Corp Method of encapsulating water insoluble oils and product thereof
US3971852A (en) 1973-06-12 1976-07-27 Polak's Frutal Works, Inc. Process of encapsulating an oil and product produced thereby
US4219569A (en) * 1978-10-10 1980-08-26 The Upjohn Company Process for treating inflammation
US4518615A (en) 1983-08-23 1985-05-21 Warner-Lambert Company Non-adhesive chewing gum base composition
US4532145A (en) 1983-12-19 1985-07-30 General Foods Corporation Fixing volatiles in an amorphous substrate and products therefrom
US4721620A (en) 1986-04-01 1988-01-26 Warner-Lambert Company Polyvinylacetate bubble gum base composition
US5093136A (en) 1991-05-08 1992-03-03 Nabisco Brands, Inc. Dual gum base bubble gum
EP0613879A4 (en) 1991-05-20 1995-05-03 Tsumura & Co PHELLODENDRIN ANALOGS AND TYPE IV ALLERGY SUPPRESSOR CONTAINING THEM AS ACTIVE INGREDIENTS.
US5266336A (en) 1991-11-12 1993-11-30 Wm. Wrigley Jr. Company High flavor impact non-tack chewing gum with reduced plasticization
US5124162A (en) 1991-11-26 1992-06-23 Kraft General Foods, Inc. Spray-dried fixed flavorants in a carbohydrate substrate and process
US5601858A (en) 1994-12-29 1997-02-11 Warner-Lambert Company Non-stick chewing gum
DE10122898A1 (de) 2001-05-11 2002-11-14 Haarmann & Reimer Gmbh Verwendung von Hydroxyflavanonen zur Maskierung des bitteren Geschmacks
US6986709B2 (en) 2001-09-21 2006-01-17 Igt Gaming device having games with variable game functions
JP2003321351A (ja) 2002-04-26 2003-11-11 Nikken Kasei Kk リパーゼ阻害剤
JP2004043354A (ja) 2002-07-11 2004-02-12 Nikken Kasei Kk ヒアルロニダーゼ阻害剤
DE102004017076A1 (de) 2004-04-07 2005-10-27 Symrise Gmbh & Co. Kg Verwendung von gamma-Aminobuttersäure zur Maskierung oder Verminderung eines unangenehmen Geschmackseindrucks sowie Zubereitungen enthaltend gamma-Aminobuttersäure
CN109134205B (zh) 2004-05-28 2022-07-19 尤尼根公司 作为双核酶强效抑制剂的二芳基烷烃
DE102004031588A1 (de) 2004-06-30 2006-02-09 Symrise Gmbh & Co. Kg Verwendung von Äpfelsäureglucosiden als Geschmacksstoffe
DE102004041496A1 (de) 2004-08-27 2006-03-02 Symrise Gmbh & Co. Kg Hydroxybenzoesäureamide und deren Verwendung zur Maskierung von bitterem Geschmack
EP2368442B1 (en) 2005-07-27 2014-12-17 Symrise AG Use of hesperetin for enhancing the sweet taste
US8679461B2 (en) 2005-07-27 2014-03-25 Symrise Ag Use of hesperetin for enhancing the sweet taste
EP1937089B1 (en) 2005-10-21 2012-08-22 Symrise AG Mixtures having a salty taste
JP4495664B2 (ja) 2005-10-21 2010-07-07 小川香料株式会社 風味増強剤及びこれを含有する茶系食品並びに茶系食品の風味増強方法
EP2001448A2 (en) * 2006-01-27 2008-12-17 Cadbury Adams USA LLC Flavor-enhancing compositions, methods of manufacture, and methods of use
US8778987B2 (en) * 2007-03-13 2014-07-15 Symrise Ag Use of 4-hydroxychalcone derivatives for masking an unpleasant taste
CA2743427A1 (en) * 2008-11-26 2010-06-03 Perio Sciences, Llc Antioxidant compositions for soft oral tissue and methods of formulation and use thereof
FR2942962B1 (fr) * 2009-03-11 2011-04-22 Oreal Utilisation d'une dihydrochalcone ou l'un de ses derives pour ameliorer l'etat de surface d'une peau fragilisee et/ou alteree
EP2253226B1 (de) 2009-05-15 2015-07-15 Leibniz-Institut für Pflanzenbiochemie (IPB) Verwendung von Hydroxyflavan-Derivaten zur Geschmacksmodifizierung
EP2298084B1 (de) 2009-08-28 2011-10-19 Symrise AG Süßmittelreduzierte Produkte, Aromamischungen dafür sowie Verfahren zum Herstellen solcher Produkte
ES2389709T3 (es) 2010-02-01 2012-10-30 Symrise Ag Uso de 1-(2,4-dihidroxifenil)-3-(3-hidroxi-4-metoxifenil)-propan-1-ona
EP2386211B1 (de) 2010-05-11 2016-08-10 Symrise AG Verwendung von rubusosid zum verringern oder unterdrücken von bestimmten unangenehmen geschmackseindrücken
JP5854592B2 (ja) 2010-11-09 2016-02-09 丸善製薬株式会社 抗酸化剤及び抗炎症剤
EP2517574B1 (de) 2011-04-29 2015-11-11 Symrise AG Bestimmte Vanillyllignane und deren Verwendung als Geschmacksverbesserer
EP2529632B1 (de) 2011-05-31 2013-08-28 Symrise AG Zimtsäureamide als würzige Geschmacksstoffe
EP2529633B1 (de) 2011-06-01 2014-08-06 Symrise AG Oral konsumierbare Zubereitungen umfassend bestimmte süß schmeckende Triterpene und Triterpenglycoside
DE202012013593U1 (de) 2011-06-30 2018-03-05 Firmenich Sa Geschmacksmodifizierendes Produkt
EP2559346B1 (en) 2011-08-15 2014-03-26 Symrise AG Oleanene-type triterpene glycosides as masking agents
EP2570036B1 (de) 2011-09-15 2014-06-18 Symrise AG Verwendung bestimmter Neoflavonoide zur Verstärkung und/oder Erzeugung eines süßen sensorischen Eindruckes
EP2570035B1 (de) 2011-09-15 2014-06-18 Symrise AG Verwendung von Neoflavonoiden zur Geschmacksmodifizierung
CA2849910A1 (en) 2011-09-30 2013-04-04 Perio Sciences, Llc Antioxidant compositions for treatment of inflammation or oxidative damage
EP2725026B1 (de) 2012-10-29 2017-09-06 Symrise AG Heterozyklische neoflavonoide mit geschmacksmaskierenden eigenschaften
EP2954785B1 (de) 2014-06-13 2018-06-06 Symrise AG Neue Stoffmischung zur Verbesserung des Süssgeschmacks enthaltend Rubusosid oder alpha-Glycosylrubusosid

Also Published As

Publication number Publication date
CN109310649A (zh) 2019-02-05
JP2019514841A (ja) 2019-06-06
RU2018141595A (ru) 2019-02-12
EP3448373A1 (en) 2019-03-06
PH12018501804A1 (en) 2019-06-17
EP3448373B1 (en) 2022-03-02
US20220226261A1 (en) 2022-07-21
CN109310649B (zh) 2021-06-29
JP6802849B2 (ja) 2020-12-23
AU2016405258A1 (en) 2018-07-19
US11759435B2 (en) 2023-09-19
WO2017186298A1 (en) 2017-11-02
KR20190021194A (ko) 2019-03-05
ES2911338T3 (es) 2022-05-18

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]