BR112017018948A2 - método - Google Patents

método

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Publication number
BR112017018948A2
BR112017018948A2 BR112017018948A BR112017018948A BR112017018948A2 BR 112017018948 A2 BR112017018948 A2 BR 112017018948A2 BR 112017018948 A BR112017018948 A BR 112017018948A BR 112017018948 A BR112017018948 A BR 112017018948A BR 112017018948 A2 BR112017018948 A2 BR 112017018948A2
Authority
BR
Brazil
Prior art keywords
subject
immune response
agent
photosensitizer
kits
Prior art date
Application number
BR112017018948A
Other languages
English (en)
Inventor
Høgset Anders
Original Assignee
Pci Biotech As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pci Biotech As filed Critical Pci Biotech As
Publication of BR112017018948A2 publication Critical patent/BR112017018948A2/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • C12N5/0602—Vertebrate cells
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  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
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Abstract

a invenção refere-se a um método de geração de uma resposta imune num sujeito, compreendendo administrar ao sujeito uma molécula antigênica, um agente fotossensibilizador, um inibidor de checkpoint e irradiar o referido sujeito com luz de um comprimento de onda eficaz para ativar o agente fotossensibilizador para gerar uma resposta imune. de preferência, o método é um método de vacinação. a invenção também fornece métodos, composições, células, usos, produtos e kits relacionados.
BR112017018948A 2015-03-05 2016-03-04 método BR112017018948A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB201503776A GB201503776D0 (en) 2015-03-05 2015-03-05 Compound and method
PCT/EP2016/054714 WO2016139362A1 (en) 2015-03-05 2016-03-04 Method

Publications (1)

Publication Number Publication Date
BR112017018948A2 true BR112017018948A2 (pt) 2018-04-17

Family

ID=52998470

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017018948A BR112017018948A2 (pt) 2015-03-05 2016-03-04 método

Country Status (10)

Country Link
US (1) US11027017B2 (pt)
EP (1) EP3265120B1 (pt)
JP (2) JP2018508533A (pt)
KR (1) KR20180026658A (pt)
CN (1) CN107847567B (pt)
AU (1) AU2016227629B2 (pt)
BR (1) BR112017018948A2 (pt)
CA (1) CA2978496A1 (pt)
GB (1) GB201503776D0 (pt)
WO (1) WO2016139362A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
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US9724404B2 (en) 2009-04-13 2017-08-08 INSERM (Institut National de la Santé et de la Recherche Médicale) HPV particles and uses thereof
WO2013119877A1 (en) 2012-02-07 2013-08-15 Aura Biosciences, Inc. Virion-derived nanospheres for selective delivery of therapeutic and diagnostic agents to cancer cells
WO2015042325A1 (en) 2013-09-18 2015-03-26 Aura Biosciences, Inc. Virus-like particle conjugates for diagnosis and treatment of tumors
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