BR112016030805A2 - Dispositivo de aerossolização, e, métodos para administração de uma medicação e de um medicamento - Google Patents

Dispositivo de aerossolização, e, métodos para administração de uma medicação e de um medicamento

Info

Publication number
BR112016030805A2
BR112016030805A2 BR112016030805A BR112016030805A BR112016030805A2 BR 112016030805 A2 BR112016030805 A2 BR 112016030805A2 BR 112016030805 A BR112016030805 A BR 112016030805A BR 112016030805 A BR112016030805 A BR 112016030805A BR 112016030805 A2 BR112016030805 A2 BR 112016030805A2
Authority
BR
Brazil
Prior art keywords
conduit
restrictor
aerosolization device
medication
user
Prior art date
Application number
BR112016030805A
Other languages
English (en)
Other versions
BR112016030805B1 (pt
Inventor
fink Jim
Molloy Lisa
Macloughlin Ronan
Elizabeth Lillis Claire
joseph casey Michael
matthew mullins John
James Hyland Kieran
Martin Grehan Joseph
Original Assignee
Dance Biopharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dance Biopharm Inc filed Critical Dance Biopharm Inc
Publication of BR112016030805A2 publication Critical patent/BR112016030805A2/pt
Publication of BR112016030805B1 publication Critical patent/BR112016030805B1/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/002Details of inhalators; Constructional features thereof with air flow regulating means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/005Sprayers or atomisers specially adapted for therapeutic purposes using ultrasonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0085Inhalators using ultrasonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0027Accessories therefor, e.g. sensors, vibrators, negative pressure pressure meter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3331Pressure; Flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/50General characteristics of the apparatus with microprocessors or computers
    • A61M2205/502User interfaces, e.g. screens or keyboards
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/50General characteristics of the apparatus with microprocessors or computers
    • A61M2205/52General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/582Means for facilitating use, e.g. by people with impaired vision by tactile feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A61M2205/584Means for facilitating use, e.g. by people with impaired vision by visual feedback having a color code
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/60General characteristics of the apparatus with identification means
    • A61M2205/6018General characteristics of the apparatus with identification means providing set-up signals for the apparatus configuration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/60General characteristics of the apparatus with identification means
    • A61M2205/6054Magnetic identification systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/60General characteristics of the apparatus with identification means
    • A61M2205/6063Optical identification systems
    • A61M2205/6072Bar codes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/82Internal energy supply devices
    • A61M2205/8206Internal energy supply devices battery-operated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/11Laminar flow

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Volume Flow (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

DISPOSITIVO DE AEROSSOLIZAÇÃO, E, MÉTODOS PARA ADMINISTRAÇÃO DE UMA MEDICAÇÃO E DE UM MEDICAMENTO. Em um aspecto, as modalidades da presente invenção proveem um dispositivo de aerossolização para assegurar a administração adequada de uma medicação aerossolizada ao sistema respiratório de um usuário. O dispositivo de aerossolização pode incluir um conduto, um gerador de aerossol, um restritor disposto dentro do conduto e um mecanismo indicador. O conduto pode incluir uma extremidade do bocal pela qual um usuário pode causar um fluxo inspiratório através do conduto. O gerador de aerossol pode incluir uma malha vibratável. O restritor pode definir uma pluralidade de aberturas dispostas ao longo de uma periferia externa do restritor configuradas para prover um aumento no diferencial de pressão que varia com um fluxo inspiratório dentro do conduto e para prover um fluxo relativamente laminar a jusante do restritor em comparação a montante do restritor. O mecanismo indicador pode indicar a um usuário um estado de um parâmetro do fluxo inspiratório em relação a uma faixa desejada predefinida.
BR112016030805-0A 2014-07-01 2015-06-24 dispositivo de aerossolização, e, métodos para administração de uma medicação e de um medicamento BR112016030805B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462019791P 2014-07-01 2014-07-01
US62/019,791 2014-07-01
US14/743,763 US10471222B2 (en) 2014-07-01 2015-06-18 Aerosolization system with flow restrictor and feedback device
US14/743,763 2015-06-18
PCT/US2015/037505 WO2016003739A1 (en) 2014-07-01 2015-06-24 Aerosolization system with flow restrictor and feedback device

Publications (2)

Publication Number Publication Date
BR112016030805A2 true BR112016030805A2 (pt) 2017-08-22
BR112016030805B1 BR112016030805B1 (pt) 2021-02-23

Family

ID=55016271

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016030805-0A BR112016030805B1 (pt) 2014-07-01 2015-06-24 dispositivo de aerossolização, e, métodos para administração de uma medicação e de um medicamento

Country Status (7)

Country Link
US (1) US10471222B2 (pt)
EP (1) EP3164222B1 (pt)
CN (1) CN106604781B (pt)
BR (1) BR112016030805B1 (pt)
ES (1) ES2731848T3 (pt)
RU (1) RU2017103007A (pt)
WO (1) WO2016003739A1 (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10842951B2 (en) 2010-01-12 2020-11-24 Aerami Therapeutics, Inc. Liquid insulin formulations and methods relating thereto
US9180261B2 (en) 2010-01-12 2015-11-10 Dance Biopharm Inc. Preservative free insulin formulations and systems and methods for aerosolizing
BR112017018060A2 (pt) 2015-02-25 2018-04-10 Dance Biopharm Inc formulação de insulina, dose de unidade, e, método de tratar um indivíduo com diabetes melito.
GB201510166D0 (en) * 2015-06-11 2015-07-29 The Technology Partnership Plc Spray delivery device
RU2738578C2 (ru) 2015-07-20 2020-12-14 Перл Терапьютикс, Инк. Системы доставки аэрозоля и соответствующие способы
CA169756S (en) 2016-02-08 2017-09-01 Nicoventures Holdings Ltd Electronic cigarette
GB201605105D0 (en) 2016-03-24 2016-05-11 Nicoventures Holdings Ltd Vapour provision apparatus
GB201605100D0 (en) 2016-03-24 2016-05-11 Nicoventures Holdings Ltd Vapour provision system
GB201605101D0 (en) 2016-03-24 2016-05-11 Nicoventures Holdings Ltd Electronic vapour provision system
GB201605102D0 (en) 2016-03-24 2016-05-11 Nicoventures Holdings Ltd Mechanical connector for electronic vapour provision system
CN109414178B (zh) 2016-05-03 2022-05-31 精呼吸股份有限公司 用于肺部健康管理的系统和方法
RU2741664C2 (ru) 2016-07-22 2021-01-28 Никовенчерс Трейдинг Лимитед Футляр для устройства предоставления пара
PL3471805T3 (pl) 2016-11-18 2020-03-31 Norton (Waterford) Limited Urządzenie do dostarczania leku zawierające części elektroniczne
AU2018211029A1 (en) 2017-01-17 2019-08-01 Corfigo, Inc. Device for ablation of tissue surfaces and related systems and methods
TW201828687A (zh) * 2017-01-25 2018-08-01 英屬開曼島商盾心科技股份有限公司 具環狀結構呼吸燈之攝影裝置
US11529476B2 (en) 2017-05-19 2022-12-20 Pneuma Respiratory, Inc. Dry powder delivery device and methods of use
US10792226B2 (en) * 2017-06-07 2020-10-06 Berkshire Biomedical, LLC Refill and dosage management devices and associated systems and methods for use with computerized oral prescription administration devices
JP2020536614A (ja) * 2017-10-04 2020-12-17 ニューマ・リスパイラトリー・インコーポレイテッド 呼吸により電気的に作動するインライン液滴送達装置および使用方法
WO2019079461A1 (en) 2017-10-17 2019-04-25 Pneuma Respiratory, Inc. NASAL MEDICATION DELIVERY APPARATUS AND METHODS OF USE
US11771852B2 (en) 2017-11-08 2023-10-03 Pneuma Respiratory, Inc. Electronic breath actuated in-line droplet delivery device with small volume ampoule and methods of use
JP2021510108A (ja) * 2018-01-08 2021-04-15 ニューマ・リスパイラトリー・インコーポレイテッド 呼吸により電気的に作動する液滴送達装置を使用した肺癌の治療
CN109498923B (zh) * 2018-12-19 2024-02-13 深圳来福士雾化医学有限公司 一种双模块的雾化装置
CN114269369A (zh) 2019-07-03 2022-04-01 艾伊拉米治疗有限公司 用于肺部施用的艾塞那肽组合物及其用途
EP4359046A1 (en) 2021-06-22 2024-05-01 Pneuma Respiratory, Inc. Droplet delivery device with push ejection

Family Cites Families (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1383761A (en) 1971-02-25 1974-02-12 Woodcraft Dc Inhalation device for use with an aerosol container
US4564129A (en) 1983-01-27 1986-01-14 Hoechst-Roussel Pharmaceuticals Inc. Dosage dispensing unit
US5759101A (en) 1986-03-10 1998-06-02 Response Reward Systems L.C. Central and remote evaluation of responses of participatory broadcast audience with automatic crediting and couponing
EP0373237A1 (de) 1988-12-13 1990-06-20 Siemens Aktiengesellschaft Inhalationsgerät, insbesondere Taschen-Inhalationsgerät
US5060642A (en) 1990-01-05 1991-10-29 Gilman Thomas H Wound dressing with air permeable bacteria impermeable reservoir
GB9015077D0 (en) 1990-07-09 1990-08-29 Riker Laboratories Inc Inhaler
EP0563120B1 (en) 1990-12-17 1997-10-01 Minnesota Mining And Manufacturing Company Inhaler
US5938117A (en) 1991-04-24 1999-08-17 Aerogen, Inc. Methods and apparatus for dispensing liquids as an atomized spray
US7628339B2 (en) 1991-04-24 2009-12-08 Novartis Pharma Ag Systems and methods for controlling fluid feed to an aerosol generator
US6540154B1 (en) 1991-04-24 2003-04-01 Aerogen, Inc. Systems and methods for controlling fluid feed to an aerosol generator
US6629646B1 (en) 1991-04-24 2003-10-07 Aerogen, Inc. Droplet ejector with oscillating tapered aperture
US5164740A (en) 1991-04-24 1992-11-17 Yehuda Ivri High frequency printing mechanism
US5363842A (en) 1991-12-20 1994-11-15 Circadian, Inc. Intelligent inhaler providing feedback to both patient and medical professional
US5320094A (en) 1992-01-10 1994-06-14 The Johns Hopkins University Method of administering insulin
US5333106A (en) 1992-10-09 1994-07-26 Circadian, Inc. Apparatus and visual display method for training in the power use of aerosol pharmaceutical inhalers
US5915378A (en) 1993-01-29 1999-06-29 Aradigm Corporation Creating an aerosolized formulation of insulin
US6024090A (en) 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
US5672581A (en) 1993-01-29 1997-09-30 Aradigm Corporation Method of administration of insulin
US6131567A (en) 1993-01-29 2000-10-17 Aradigm Corporation Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin
US7448375B2 (en) 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US5364838A (en) 1993-01-29 1994-11-15 Miris Medical Corporation Method of administration of insulin
US5888477A (en) 1993-01-29 1999-03-30 Aradigm Corporation Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin
US5743250A (en) * 1993-01-29 1998-04-28 Aradigm Corporation Insulin delivery enhanced by coached breathing
CH686872A5 (de) 1993-08-09 1996-07-31 Disetronic Ag Medizinisches Inhalationsgeraet.
DE69413989T2 (de) 1993-08-18 1999-04-08 Fisons Plc Inhalator mit atemstromregelung
US5655520A (en) 1993-08-23 1997-08-12 Howe; Harvey James Flexible valve for administering constant flow rates of medicine from a nebulizer
US5479920A (en) 1994-03-01 1996-01-02 Vortran Medical Technology, Inc. Breath actuated medicinal aerosol delivery apparatus
US5522385A (en) 1994-09-27 1996-06-04 Aradigm Corporation Dynamic particle size control for aerosolized drug delivery
US6427682B1 (en) 1995-04-05 2002-08-06 Aerogen, Inc. Methods and apparatus for aerosolizing a substance
US6014970A (en) 1998-06-11 2000-01-18 Aerogen, Inc. Methods and apparatus for storing chemical compounds in a portable inhaler
US5758637A (en) 1995-08-31 1998-06-02 Aerogen, Inc. Liquid dispensing apparatus and methods
US6782886B2 (en) 1995-04-05 2004-08-31 Aerogen, Inc. Metering pumps for an aerosolizer
US6085740A (en) 1996-02-21 2000-07-11 Aerogen, Inc. Liquid dispensing apparatus and methods
US6205999B1 (en) 1995-04-05 2001-03-27 Aerogen, Inc. Methods and apparatus for storing chemical compounds in a portable inhaler
US5586550A (en) 1995-08-31 1996-12-24 Fluid Propulsion Technologies, Inc. Apparatus and methods for the delivery of therapeutic liquids to the respiratory system
US5474059A (en) * 1995-04-08 1995-12-12 Cooper; Guy F. Aerosol dispensing apparatus for dispensing a medicated vapor into the lungs of a patient
WO1998022290A1 (en) 1996-11-18 1998-05-28 Pbt International Ltd. An inkjet cartridge refill device
US20060239930A1 (en) 1997-08-04 2006-10-26 Herbert Lamche Process for nebulizing aqueous compositions containing highly concentrated insulin
CN1292714B (zh) * 1998-03-16 2012-08-01 诺瓦帝斯公司 气溶胶化活性剂的输送
US6312665B1 (en) 1998-12-21 2001-11-06 Generex Pharmaceuticals Incorporated Aerosol formulations for buccal and pulmonary application
DE19912461B4 (de) 1999-03-19 2006-07-20 GSF - Forschungszentrum für Umwelt und Gesundheit GmbH Vorrichtung zur Flußbegrenzung bei niedrigen Differenzdrücken
US6235177B1 (en) 1999-09-09 2001-05-22 Aerogen, Inc. Method for the construction of an aperture plate for dispensing liquid droplets
US6089260A (en) 1999-09-10 2000-07-18 S. C. Johnson & Son, Inc. Nested duckbill check valves
GB0003197D0 (en) 2000-02-11 2000-04-05 Aid Medic Ltd Improvements in and relating to controlling drug delivery
GB2360219A (en) 2000-03-18 2001-09-19 Astrazeneca Uk Ltd Inhaler
US6968840B2 (en) 2000-05-05 2005-11-29 Aerogen, Inc. Methods and systems for operating an aerosol generator
US6948491B2 (en) 2001-03-20 2005-09-27 Aerogen, Inc. Convertible fluid feed system with comformable reservoir and methods
US7100600B2 (en) 2001-03-20 2006-09-05 Aerogen, Inc. Fluid filled ampoules and methods for their use in aerosolizers
US6626171B2 (en) 2000-05-12 2003-09-30 Iep Pharmaceutical Devices Inc. Powder/liquid metering valve
JP4147234B2 (ja) 2004-09-27 2008-09-10 キヤノン株式会社 吐出用液体、吐出方法、カートリッジ及び吐出装置
JP3687090B2 (ja) 2000-12-19 2005-08-24 ヤマハ株式会社 音源付き記憶装置
ATE299729T1 (de) 2001-03-15 2005-08-15 Us Gov Health & Human Serv Vernebler mit kühlkammer
US6732944B2 (en) 2001-05-02 2004-05-11 Aerogen, Inc. Base isolated nebulizing device and methods
DE10126807C2 (de) 2001-06-01 2003-12-04 Pari Gmbh Inhalationstherapiegerät mit einem Ventil zur Begrenzung des Inspirationsflusses
US20030068361A1 (en) 2001-10-09 2003-04-10 Rimona Margalit Liposome-encapsulated insulin formulations
US6543701B1 (en) 2001-12-21 2003-04-08 Tung-Huang Ho Pocket-type ultrasonic atomizer structure
US6904908B2 (en) * 2002-05-21 2005-06-14 Trudell Medical International Visual indicator for an aerosol medication delivery apparatus and system
US7185651B2 (en) 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
GB0222295D0 (en) 2002-09-25 2002-10-30 3M Innovative Properties Co Breath actuated medicament dispensing devices
GB2395437C (en) 2002-11-20 2010-10-20 Profile Respiratory Systems Ltd Improved inhalation method and apparatus
US7913688B2 (en) 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
US7683029B2 (en) 2003-05-07 2010-03-23 Philip Morris Usa Inc. Liquid aerosol formulations containing insulin and aerosol generating devices and methods for generating aerosolized insulin
US7600512B2 (en) 2003-07-14 2009-10-13 Vortran Medical Technology 1, Inc. Inhaler with breath actuated dose counter
US8616195B2 (en) * 2003-07-18 2013-12-31 Novartis Ag Nebuliser for the production of aerosolized medication
US7819115B2 (en) 2004-01-30 2010-10-26 Hewlett-Packard Development Company, L.P. Inhalers and methods of controlling airflow in inhalers
US7712466B2 (en) 2004-02-20 2010-05-11 Pneumoflex Systems, Llc Intra-oral nebulizer
US7364571B2 (en) 2004-03-02 2008-04-29 Schinazi Robert G Flow restrictor device for a medical apparatus
WO2006062449A1 (en) 2004-12-10 2006-06-15 Ernst Hörlins Ingenjörsbyra AB Breath actuated dose inhaler
EP1848541A4 (en) 2005-02-07 2013-01-16 Pharmalight Inc METHOD AND DEVICE FOR OPHTHALMIC DELIVERY OF PHARMACEUTICALLY ACTIVE INGREDIENTS
US7219664B2 (en) 2005-04-28 2007-05-22 Kos Life Sciences, Inc. Breath actuated inhaler
ES2290827T3 (es) 2005-07-06 2008-02-16 Activaero Gmbh Valvula regulable y dispositivo para inhalar.
JP4765526B2 (ja) 2005-10-04 2011-09-07 オムロンヘルスケア株式会社 吸入器および吸入器用マウスピース
CA2626357A1 (en) 2005-10-20 2007-04-26 Nastech Pharmaceutical Company Inc. Intranasal administration of rapid acting insulin
DE102005056488A1 (de) 2005-11-21 2007-05-24 Ing. Erich Pfeiffer Gmbh Spender und Dosierbaugruppe für die Mediumdosierung
US7802569B2 (en) * 2005-12-22 2010-09-28 Kaer Biotherapeutics Corporation Aerosol processing and inhalation method and system for high dose rate aerosol drug delivery
US20100154794A1 (en) 2006-03-21 2010-06-24 Valentin Boris N Inhaler Flow Channel
WO2008097645A1 (en) 2007-02-08 2008-08-14 Aerovectrx Corporation Aerosol delivery systems and methods
WO2008103649A2 (en) 2007-02-20 2008-08-28 Conagra Foods Rdm, Inc. Food dispensing apparatus
US20090241948A1 (en) * 2007-03-28 2009-10-01 Dermot Joseph Clancy Humidification in breathing circuits
ES2398921T3 (es) 2007-08-02 2013-03-22 Activaero Gmbh Dispositivo y sistema para dirigir partículas aerosolizadas a un área específica de los pulmones
WO2009049304A1 (en) 2007-10-12 2009-04-16 Map Pharmaceuticals, Inc. Inhalation drug delivery
WO2010003846A1 (en) 2008-07-10 2010-01-14 Bang & Olufsen Medicom A/S An inhaler and a method of operating it
JP5746625B2 (ja) 2008-08-25 2015-07-08 コーニンクレッカ フィリップス エヌ ヴェ 音声指示を供給する呼吸器系薬物送達装置
US8695587B2 (en) 2008-09-26 2014-04-15 Incube Labs, Llc Controlled inhaler for distributing inhalant according to inhalation velocity
US8495998B2 (en) 2009-06-17 2013-07-30 British American Tobacco (Investments) Limited Inhaler
US20130269684A1 (en) 2012-04-16 2013-10-17 Dance Pharmaceuticals, Inc. Methods and systems for supplying aerosolization devices with liquid medicaments
US9180261B2 (en) 2010-01-12 2015-11-10 Dance Biopharm Inc. Preservative free insulin formulations and systems and methods for aerosolizing
US8944050B2 (en) 2010-08-13 2015-02-03 The Corporation Of Mercer University Inhalation airflow regulation devices and methods of using the same
US9381303B2 (en) 2010-08-16 2016-07-05 Becton, Dickinson And Company Sterility barrier for pen needle and storage container therefor
CA3071911C (en) 2010-08-23 2023-01-17 Darren Rubin Systems and methods of aerosol delivery with airflow regulation
US20130004645A1 (en) 2011-06-30 2013-01-03 Joseph Paglino Sweet onion sauce and method of manufacturing same
HUE043424T2 (hu) 2011-12-27 2019-08-28 Vectura Gmbh Inhalációs készülék visszacsatolásos rendszerrel
US20130269694A1 (en) 2012-04-16 2013-10-17 Dance Pharmaceuticals, Inc. Inhaler controlled by mobile device
EP2662138A1 (en) 2012-05-08 2013-11-13 Roche Diagniostics GmbH Microfluidic dispenser, cartridge and analysis system for analyzing a biological sample
DK2724741T3 (en) 2012-10-26 2017-09-18 Vectura Gmbh Inhalation device for use in aerosol treatment
JP2014175096A (ja) 2013-03-06 2014-09-22 Toshiba Lighting & Technology Corp 照明装置
RU2669930C2 (ru) 2013-04-16 2018-10-17 Данс Байофарм Инк. Дозирование жидкостей и способы дозирования жидкостей

Also Published As

Publication number Publication date
EP3164222B1 (en) 2019-03-20
US10471222B2 (en) 2019-11-12
US20160001018A1 (en) 2016-01-07
CN106604781B (zh) 2020-06-30
EP3164222A1 (en) 2017-05-10
BR112016030805B1 (pt) 2021-02-23
RU2017103007A3 (pt) 2019-01-18
ES2731848T3 (es) 2019-11-19
RU2017103007A (ru) 2018-08-02
WO2016003739A1 (en) 2016-01-07
CN106604781A (zh) 2017-04-26
EP3164222A4 (en) 2018-02-28

Similar Documents

Publication Publication Date Title
BR112016030805A2 (pt) Dispositivo de aerossolização, e, métodos para administração de uma medicação e de um medicamento
EA201692005A1 (ru) Ингаляционный тренажер и система для тренировки процесса ингаляции
PH12018501143A1 (en) Nicotine powder delivery system
MX2017000056A (es) Dispositivo inhalador con regulacion de flujo.
PH12016501719B1 (en) Flavoured nicotine powder inhaler
WO2014144717A3 (en) Medical breathing apparatus
PH12016501382A1 (en) Nicotine powder delivery system with airflow management means
EP3914324A4 (en) ELECTRONIC BREATH ACTUATED DRIPPING SYSTEMS WITH DOSING FUNCTION, INHALATION TOPOGRAPHIC METHODS AND RELATED METHODS OF USE
PT3137143T (pt) Sistemas para dispensar gás terapêutico a doentes que dele têm necessidade, recebendo gás respiratório de um ventilador que varia pelo menos a pressão e / ou o fluxo usando medição de fluxo de gás terapêutico (no) melhorada
MX2016014089A (es) Inhalador de polvo de nicotina.
AU2018264061B2 (en) Inhaler
GB2546949A (en) Substance delivery arrangement for gas therapy device
MA42708A (fr) Dispositif d'administration nasale en ligne
GB2538405A (en) Sealing force detection enabled, therapeutic fluid delivery device
MX2017006912A (es) Inhalador de polvo seco.
CR20190299A (es) Formas de administración farmacéutica que contienen inhibidores de canales task-1 y task-3 y su uso para el tratamiento de transtornos respiratorios
BR112014013420A2 (pt) revestimento termoplástico para defumados
WO2015174864A8 (en) Methods and apparatus for flow therapy
MX2016016201A (es) Particulas inhalables que comprenden una combinacion de un anticolinergico, un corticosteroide y un beta-adrenergico.
MX2020002927A (es) Dispositivos y metodos para entregar fluido a una cavidad nasal.
BR112015011246A2 (pt) aparelho para entregar nasalmente uma ventilação com jato supraglótica método e sistema para ventilação e/ou oxigenação de um indivíduo com respiração comprometida; e método para a sincronização de respiração de um indivíduo com um ventilador de jato
GB202000254D0 (en) An efficient drug delivery device based on the respiratory medicine department
AR102900A1 (es) Método y monitoreo de inhalación
Scott et al. A46 ACUTE RESPIRATORY FAILURE: Comparison Of A Nonrebreathing Mask And Oxymulti Mask Prototype: An Analysis Of Oxygen Concentrations Measured In The Trachea Using A High-Fidelity Simulator
MD1005Z (ro) Inhalator

Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/06/2015, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 9A ANUIDADE.