BR112016030758B8 - Uso de células estromais multipotentes derivadas de tecido adiposo mesenquimal - Google Patents
Uso de células estromais multipotentes derivadas de tecido adiposo mesenquimalInfo
- Publication number
- BR112016030758B8 BR112016030758B8 BR112016030758A BR112016030758A BR112016030758B8 BR 112016030758 B8 BR112016030758 B8 BR 112016030758B8 BR 112016030758 A BR112016030758 A BR 112016030758A BR 112016030758 A BR112016030758 A BR 112016030758A BR 112016030758 B8 BR112016030758 B8 BR 112016030758B8
- Authority
- BR
- Brazil
- Prior art keywords
- strome
- multipotent
- adipose tissue
- cells derived
- mesenchymal
- Prior art date
Links
- 210000000577 adipose tissue Anatomy 0.000 title 1
- 206010040047 Sepsis Diseases 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 210000002536 stromal cell Anatomy 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0031—Rectum, anus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Engineering & Computer Science (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Wood Science & Technology (AREA)
- Otolaryngology (AREA)
- Nutrition Science (AREA)
- Pain & Pain Management (AREA)
- Dispersion Chemistry (AREA)
- Neurosurgery (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Physiology (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14175095.0 | 2014-06-30 | ||
| EP14175095 | 2014-06-30 | ||
| PCT/IB2015/054923 WO2016001846A1 (en) | 2014-06-30 | 2015-06-30 | Mesenchymal stromal cells for treating sepsis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR112016030758A2 BR112016030758A2 (enExample) | 2017-08-22 |
| BR112016030758B1 BR112016030758B1 (pt) | 2021-10-13 |
| BR112016030758B8 true BR112016030758B8 (pt) | 2022-10-25 |
Family
ID=51033023
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112016030758A BR112016030758B8 (pt) | 2014-06-30 | 2015-06-30 | Uso de células estromais multipotentes derivadas de tecido adiposo mesenquimal |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20170151284A1 (enExample) |
| EP (1) | EP3160481B1 (enExample) |
| JP (1) | JP6722599B2 (enExample) |
| KR (1) | KR102213527B1 (enExample) |
| CN (1) | CN106573017B (enExample) |
| AU (1) | AU2015283662B2 (enExample) |
| BR (1) | BR112016030758B8 (enExample) |
| CA (1) | CA2953884C (enExample) |
| IL (1) | IL249814B (enExample) |
| MX (1) | MX381544B (enExample) |
| NZ (1) | NZ727950A (enExample) |
| RU (1) | RU2715866C2 (enExample) |
| SG (1) | SG11201610844PA (enExample) |
| WO (1) | WO2016001846A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11518982B2 (en) * | 2015-12-01 | 2022-12-06 | Adiposeeds, Inc. | Method for manufacturing mesenchymal cell line derived from vertebrate animal adipose tissue |
| US11701389B2 (en) * | 2016-03-09 | 2023-07-18 | Emory University | Methods of preserving mesenchymal stem cells |
| GB201604304D0 (en) * | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| WO2018158542A1 (fr) | 2017-02-28 | 2018-09-07 | Université De Lorraine | Cellules souches mesenchymateuses issues de la gelée de wharton pur le traitement du sepsis |
| WO2019084010A1 (en) | 2017-10-26 | 2019-05-02 | Emory University | MCL-1 INHIBITORS, COMPOSITIONS AND USES IN CANCER CARE |
| JP7343091B2 (ja) * | 2018-06-05 | 2023-09-12 | メディポスト・カンパニー・リミテッド | 軟骨損傷関連の疾患を処置するための、ヒアルロン酸及び幹細胞を含む医薬組成物 |
| CA3116196A1 (en) * | 2018-10-29 | 2020-05-07 | Ottawa Hospital Research Institute | Genetically-engineered mesenchymal stem cells overexpressing aoah and uses thereof |
| US20230086254A1 (en) * | 2020-01-30 | 2023-03-23 | Jcr Pharmaceuticals Co., Ltd. | Medicinal composition comprising dental pulp-derived cells |
| CA3220002A1 (en) * | 2021-05-13 | 2022-11-17 | Primegen Us, Inc. | Methods and compositions for treating liver disease |
| CN113398150A (zh) * | 2021-06-18 | 2021-09-17 | 卡替(上海)生物技术有限公司 | 牙髓间充质干细胞在脓毒症治疗中的应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR9307550A (pt) | 1992-12-02 | 1999-05-25 | Shell Int Research | Composto fungicida processo para a preparação de um composto fungicida composição fungicida processo de combate aos fungos em um local e uso |
| WO1995002698A1 (en) | 1993-07-12 | 1995-01-26 | Life Technologies, Inc. | Composition and methods for transfecting eukaryotic cells |
| US6051429A (en) | 1995-06-07 | 2000-04-18 | Life Technologies, Inc. | Peptide-enhanced cationic lipid transfections |
| DE69634084T2 (de) | 1995-06-07 | 2005-12-08 | Inex Pharmaceuticals Corp. | Herstellung von lipid-nukleinsäure partikeln duch ein hydrophobische lipid-nukleinsäuree komplexe zwischenprodukt und zur verwendung in der gentransfer |
| US5744335A (en) | 1995-09-19 | 1998-04-28 | Mirus Corporation | Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein |
| US5705308A (en) | 1996-09-30 | 1998-01-06 | Eastman Kodak Company | Infrared-sensitive, negative-working diazonaphthoquinone imaging composition and element |
| US6777231B1 (en) | 1999-03-10 | 2004-08-17 | The Regents Of The University Of California | Adipose-derived stem cells and lattices |
| EP2298861B1 (en) * | 2004-03-22 | 2017-09-13 | Mesoblast International Sàrl | Mesenchymal stem cells and uses therefor |
| JP5925408B2 (ja) | 2005-09-23 | 2016-05-25 | タイジェニックス、ソシエダッド、アノニマ、ウニペルソナルＴｉｇｅｎｉｘ Ｓ．Ａ．Ｕ． | 免疫調節活性を有する細胞集団、単離方法および使用 |
| GB0814249D0 (en) * | 2008-08-04 | 2008-09-10 | Cellerix Sa | Uses of mesenchymal stem cells |
| CN109432126B (zh) * | 2011-03-11 | 2022-06-14 | 儿童医学中心公司 | 与间充质干细胞外来体相关的方法和组合物 |
| JP2014016782A (ja) * | 2012-07-09 | 2014-01-30 | Toshiba Corp | 情報処理装置およびプログラム |
| US20140134140A1 (en) * | 2012-11-09 | 2014-05-15 | Case Western Reserve University | Mesenchymal stem cell compositions for the treatment of microbial infections |
-
2015
- 2015-06-30 SG SG11201610844PA patent/SG11201610844PA/en unknown
- 2015-06-30 EP EP15742102.5A patent/EP3160481B1/en active Active
- 2015-06-30 KR KR1020177002380A patent/KR102213527B1/ko active Active
- 2015-06-30 RU RU2016151738A patent/RU2715866C2/ru active
- 2015-06-30 US US15/323,373 patent/US20170151284A1/en not_active Abandoned
- 2015-06-30 NZ NZ727950A patent/NZ727950A/en unknown
- 2015-06-30 CN CN201580042833.7A patent/CN106573017B/zh active Active
- 2015-06-30 JP JP2016575950A patent/JP6722599B2/ja active Active
- 2015-06-30 BR BR112016030758A patent/BR112016030758B8/pt active IP Right Grant
- 2015-06-30 MX MX2017000142A patent/MX381544B/es unknown
- 2015-06-30 WO PCT/IB2015/054923 patent/WO2016001846A1/en not_active Ceased
- 2015-06-30 CA CA2953884A patent/CA2953884C/en active Active
- 2015-06-30 AU AU2015283662A patent/AU2015283662B2/en active Active
-
2016
- 2016-12-28 IL IL249814A patent/IL249814B/en active IP Right Grant
-
2020
- 2020-08-14 US US16/994,379 patent/US20200376038A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MX381544B (es) | 2025-03-12 |
| SG11201610844PA (en) | 2017-01-27 |
| BR112016030758B1 (pt) | 2021-10-13 |
| IL249814A0 (en) | 2017-03-30 |
| CA2953884A1 (en) | 2016-01-07 |
| CA2953884C (en) | 2022-12-06 |
| MX2017000142A (es) | 2017-07-28 |
| RU2016151738A (ru) | 2018-07-30 |
| WO2016001846A1 (en) | 2016-01-07 |
| IL249814B (en) | 2020-02-27 |
| US20170151284A1 (en) | 2017-06-01 |
| RU2715866C2 (ru) | 2020-03-03 |
| EP3160481A1 (en) | 2017-05-03 |
| KR102213527B1 (ko) | 2021-02-09 |
| AU2015283662A1 (en) | 2017-01-19 |
| JP6722599B2 (ja) | 2020-07-15 |
| NZ727950A (en) | 2022-07-01 |
| KR20170021343A (ko) | 2017-02-27 |
| US20200376038A1 (en) | 2020-12-03 |
| RU2016151738A3 (enExample) | 2019-01-30 |
| JP2017520583A (ja) | 2017-07-27 |
| BR112016030758A2 (enExample) | 2017-08-22 |
| CN106573017B (zh) | 2021-06-11 |
| EP3160481B1 (en) | 2020-09-09 |
| AU2015283662B2 (en) | 2020-09-24 |
| CN106573017A (zh) | 2017-04-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112016030758B8 (pt) | Uso de células estromais multipotentes derivadas de tecido adiposo mesenquimal | |
| MX2023010124A (es) | Generacion de acido peroxiformico a traves de formiato de alcohol polihidrico. | |
| CL2016002751A1 (es) | Compuestos y composiciones como agonistas del receptor tipo toll 7. | |
| EA201692529A1 (ru) | Способы и композиции для лечения расстройств с использованием фоллистатиновых полипептидов | |
| MX2016002571A (es) | Regulador de ph de transduccion. | |
| BR112016025132A2 (pt) | compostos polifluorados agindo como inibidores de tirosina quinase de bruton | |
| DK3692857T3 (da) | Indretning til levering af hudplejesammensætning | |
| EA201790273A1 (ru) | Флагеллиновые композиции и их применение | |
| UY33917A (es) | ?composiciones para recubrimiento que comprenden submicropartículas que comprenden carbonato de calcio, proceso para prepararlas, y uso de las submicropartículas?. | |
| MX390739B (es) | Composicion de hueso comprimido y metodo para usar la misma. | |
| BR112018008931A8 (pt) | ?compostos para tratamento de distúrbios hipoproliferativos? | |
| MX362471B (es) | Composiciones para el cuidado bucal que tienen estabilidad mejorada. | |
| LT3250202T (lt) | Kompozicija, skirta naudoti kraujodaros kamieninių ląstelių po transplantacijos prigijimo pagerinimui | |
| DOP2016000073A (es) | Composiciones y métodos para inhibir la expresión del gen alas1 | |
| MX2021000773A (es) | Composiciones que comprenden acido 15-hidroxieicosapentaenoico (15-hepe) y metodos de uso del mismo. | |
| DK3828203T3 (da) | Sammensætninger og fremgangsmåder til behandling af fedtvævsopbygning | |
| MX2015003701A (es) | Composiciones para tratamiento. | |
| EP3387112A4 (en) | METHOD FOR RECONNECTING BROWN FAT CELLS DERIVED FROM VARIOUS PLURIPOTENT STEM CELLS | |
| DOP2017000146A (es) | Pirazolpiridinaminas como inhibidores de mknk1 y mknk2 | |
| BR112017009289A2 (pt) | métodos de administrar composições de amantadina | |
| NZ703345A (en) | Compositions and methods for reducing frequency and/or severity of headache | |
| DK3189844T3 (da) | Pluripotent stamcelle til behandling af diabetisk hudsår | |
| MX2016009655A (es) | Metodos novedosos para el tratamiento del cancer. | |
| EP3300506A4 (en) | Use of mesenchymal stem cells in treating osteoarthritis | |
| GT201500056S (es) | Aparato para peinar el cabello |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/06/2015, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B25A | Requested transfer of rights approved |
Owner name: TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) |