BR112016021282A2 - - Google Patents
Info
- Publication number
- BR112016021282A2 BR112016021282A2 BR112016021282A BR112016021282A BR112016021282A2 BR 112016021282 A2 BR112016021282 A2 BR 112016021282A2 BR 112016021282 A BR112016021282 A BR 112016021282A BR 112016021282 A BR112016021282 A BR 112016021282A BR 112016021282 A2 BR112016021282 A2 BR 112016021282A2
- Authority
- BR
- Brazil
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Artificial Filaments (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461955532P | 2014-03-19 | 2014-03-19 | |
PCT/US2015/021464 WO2015143154A1 (en) | 2014-03-19 | 2015-03-19 | Antifungal compound process |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112016021282A2 true BR112016021282A2 (US07935481-20110503-C00024.png) | 2017-08-15 |
BR112016021282A8 BR112016021282A8 (pt) | 2021-07-20 |
Family
ID=54145313
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016021282A BR112016021282A8 (pt) | 2014-03-19 | 2015-03-19 | processos para a preparação de compostos antifúngicos e os referidos compostos |
Country Status (12)
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX371291B (es) | 2014-03-19 | 2020-01-24 | Viamet Pharmaceuticals Nc Inc | 2-(2,4-difluorofenil)-1,1-difluoro-1-(5-sustituido-piridin-2-il)- 3-(1h-tetrazol-1-il)propan-2-oles y procedimientos para su preparacion. |
JP6572234B2 (ja) * | 2014-03-19 | 2019-09-04 | ヴィアメット ファーマスーティカルズ(エヌシー),インコーポレイテッド | 抗真菌化合物の調製方法 |
US10000465B2 (en) | 2014-03-19 | 2018-06-19 | Mycovia Pharmaceuticals, Inc. | Antifungal compound process |
WO2015143192A1 (en) * | 2014-03-19 | 2015-09-24 | Viamet Pharmaceuticals, Inc. | 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1h-tetrazol-1-yl)propan-2-ols and processes for their preparation |
JP2017507991A (ja) | 2014-03-19 | 2017-03-23 | ヴィアメット ファーマスーティカルズ,インコーポレイテッド | 抗真菌化合物の調製方法 |
US10017494B2 (en) | 2014-03-19 | 2018-07-10 | Mycovia Pharmaceuticals, Inc. | Antifungal compound process |
AU2015231208B2 (en) | 2014-03-19 | 2019-04-04 | Mycovia Pharmaceuticals, Inc. | Antifungal compound process |
WO2015143142A1 (en) | 2014-03-19 | 2015-09-24 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
CN109970629B (zh) | 2014-03-19 | 2023-04-11 | 迈科维亚医药公司 | 抗真菌化合物的制备方法 |
BR112018005194B1 (pt) | 2015-09-18 | 2022-11-08 | Vps-3, Inc | Processo para preparar um composto antifúngico |
JP2021502402A (ja) | 2017-11-13 | 2021-01-28 | バイエル アクチェンゲゼルシャフトBayer Aktiengesellschaft | テトラゾリルプロピル誘導体および殺真菌剤としてのそれらの使用 |
CN114573557B (zh) * | 2022-03-28 | 2024-03-08 | 浙江天宇药业股份有限公司 | 一种奥特康唑的制备方法 |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2854015B2 (de) | 1978-12-14 | 1980-10-09 | Dynamit Nobel Ag, 5210 Troisdorf | Verfahren zur Herstellung von !H-TetrazoI-1-essigsauren und bestimmter Ester derselben |
JP2000344744A (ja) | 1999-06-04 | 2000-12-12 | Ss Pharmaceut Co Ltd | アセトフェノン誘導体およびその製法 |
US8198448B2 (en) | 2006-07-14 | 2012-06-12 | Amgen Inc. | Fused heterocyclic derivatives and methods of use |
KR100889937B1 (ko) | 2007-08-06 | 2009-03-20 | 한미약품 주식회사 | 보리코나졸의 제조방법 |
KR101109215B1 (ko) | 2009-06-17 | 2012-01-30 | 보령제약 주식회사 | 보리코나졸의 신규 중간체 및 이를 이용한 보리코나졸의 제조방법 |
EP2443099A1 (en) | 2009-06-18 | 2012-04-25 | Basf Se | Antifungal 1, 2, 4-triazolyl derivatives having a 5- sulfur substituent |
CN103097374B (zh) | 2010-04-24 | 2015-01-07 | 威尔金制药有限公司 | 金属酶抑制剂化合物 |
MX351943B (es) | 2011-06-19 | 2017-11-03 | Viamet Pharmaceuticals Nc Inc | Compuestos inhibidores de metaloenzima. |
US8901121B2 (en) | 2011-06-19 | 2014-12-02 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitor compounds |
EA025266B1 (ru) | 2011-06-23 | 2016-12-30 | Ваймет Фармасьютикалс, Инк. | Соединения, ингибирующие металлоферменты |
TR201807418T4 (tr) | 2011-12-11 | 2018-06-21 | Viamet Pharmaceuticals Nc Inc | Metalloenzim inhibitör bileşikleri. |
BR112014017751B1 (pt) * | 2012-01-20 | 2021-12-07 | Mycovia Pharmaceuticals, Inc | Compostos inibidores de metaloenzima, composições compreendendo os ditos compostos e uso dos ditos compostos |
AU2013209520A1 (en) | 2012-01-20 | 2014-08-28 | Viamet Pharmaceuticals (NC), Inc. | Metalloenzyme inhibitor compounds |
EP2894981B1 (en) | 2012-09-12 | 2019-12-04 | Dow AgroSciences LLC | Metalloenzyme inhibitor compounds |
AU2014209107B2 (en) | 2013-01-28 | 2018-04-12 | Viamet Pharmaceuticals (NC), Inc. | Metalloenzyme inhibitor compounds |
WO2014165861A1 (en) | 2013-04-05 | 2014-10-09 | The Regents Of The University Of California | Metal-catalyzed coupling of aryl and vinyl halides with alpha, alpha-difluorocarbonyl compounds |
JP6387401B2 (ja) | 2013-05-28 | 2018-09-05 | ヴィアメット ファーマスーティカルズ(エヌシー),インコーポレイテッド | 殺真菌組成物 |
EP3008051A4 (en) | 2013-06-12 | 2017-03-01 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitor compounds |
AU2015231208B2 (en) | 2014-03-19 | 2019-04-04 | Mycovia Pharmaceuticals, Inc. | Antifungal compound process |
CN109970629B (zh) | 2014-03-19 | 2023-04-11 | 迈科维亚医药公司 | 抗真菌化合物的制备方法 |
CA2942927A1 (en) | 2014-03-19 | 2015-09-24 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
US10000465B2 (en) | 2014-03-19 | 2018-06-19 | Mycovia Pharmaceuticals, Inc. | Antifungal compound process |
WO2015143192A1 (en) | 2014-03-19 | 2015-09-24 | Viamet Pharmaceuticals, Inc. | 2-(2,4-difluorophenyl)-1,1-difluoro-1-(5-substituted-pyridin-2-yl)-3-(1h-tetrazol-1-yl)propan-2-ols and processes for their preparation |
JP2017507991A (ja) | 2014-03-19 | 2017-03-23 | ヴィアメット ファーマスーティカルズ,インコーポレイテッド | 抗真菌化合物の調製方法 |
US10017494B2 (en) | 2014-03-19 | 2018-07-10 | Mycovia Pharmaceuticals, Inc. | Antifungal compound process |
WO2015143142A1 (en) | 2014-03-19 | 2015-09-24 | Viamet Pharmaceuticals, Inc. | Antifungal compound process |
MX371291B (es) | 2014-03-19 | 2020-01-24 | Viamet Pharmaceuticals Nc Inc | 2-(2,4-difluorofenil)-1,1-difluoro-1-(5-sustituido-piridin-2-il)- 3-(1h-tetrazol-1-il)propan-2-oles y procedimientos para su preparacion. |
JP6572234B2 (ja) | 2014-03-19 | 2019-09-04 | ヴィアメット ファーマスーティカルズ(エヌシー),インコーポレイテッド | 抗真菌化合物の調製方法 |
SI3271347T1 (sl) | 2015-03-19 | 2022-11-30 | Mycovia Pharmaceuticals, Inc. | Protiglivične spojine in postopki za izdelavo |
EP3702353B1 (en) | 2015-05-18 | 2023-07-05 | Mycovia Pharmaceuticals, Inc. | Antifungal compositions |
BR112018005194B1 (pt) | 2015-09-18 | 2022-11-08 | Vps-3, Inc | Processo para preparar um composto antifúngico |
KR20180101343A (ko) | 2015-11-17 | 2018-09-12 | 다우 아그로사이언시즈 엘엘씨 | 4-((6-(2-(2,4-디플루오로페닐)-1,1-디플루오로-2-옥소에틸)피리딘-3-일)옥시)벤조니트릴 및 제조방법 |
JP2018533635A (ja) | 2015-11-17 | 2018-11-15 | ダウ アグロサイエンシィズ エルエルシー | 4−((6−(2−(2,4−ジフルオロフェニル)−1,1−ジフルオロ−2−ヒドロキシ−3−(1h−1,2,4−トリアゾ−ル−1−イル)プロピル)ピリジン−3−イル)オキシ)ベンゾニトリル及び製造方法 |
AR106728A1 (es) | 2015-11-17 | 2018-02-14 | Viamet Pharmaceuticals Inc | 4-((6-(2-(2,4difluorofenil)-1,1-difluoro-2-hidroxi-3-(1h-1,2,4-triazol-1-il)propil)piridin-3-il)oxi)benzonitrilo y proceso para su preparación |
WO2017087619A1 (en) | 2015-11-17 | 2017-05-26 | Viamet Pharmaceuticals, Inc. | 4-((6-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(1h-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile and processes of preparation |
EP3397629B1 (en) | 2015-12-30 | 2023-04-19 | NQP 1598, Ltd. | Metalloenzyme inhibitor compounds |
-
2015
- 2015-03-19 AU AU2015231208A patent/AU2015231208B2/en not_active Ceased
- 2015-03-19 KR KR1020167025610A patent/KR20160138013A/ko not_active Application Discontinuation
- 2015-03-19 JP JP2016557965A patent/JP6606508B2/ja not_active Expired - Fee Related
- 2015-03-19 ES ES15764259T patent/ES2800905T3/es active Active
- 2015-03-19 MX MX2016012053A patent/MX369357B/es active IP Right Grant
- 2015-03-19 EP EP15764259.6A patent/EP3119771B1/en active Active
- 2015-03-19 US US15/126,359 patent/US10077250B2/en active Active
- 2015-03-19 EA EA201691648A patent/EA201691648A1/ru unknown
- 2015-03-19 WO PCT/US2015/021464 patent/WO2015143154A1/en active Application Filing
- 2015-03-19 BR BR112016021282A patent/BR112016021282A8/pt not_active Application Discontinuation
- 2015-03-19 CA CA2942930A patent/CA2942930A1/en not_active Abandoned
- 2015-03-19 CN CN201580014312.0A patent/CN106459022B/zh not_active Expired - Fee Related
-
2018
- 2018-09-17 US US16/132,973 patent/US20190177298A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP3119771A4 (en) | 2017-11-22 |
US10077250B2 (en) | 2018-09-18 |
CA2942930A1 (en) | 2015-09-24 |
EA201691648A1 (ru) | 2017-01-30 |
US20190177298A1 (en) | 2019-06-13 |
CN106459022A (zh) | 2017-02-22 |
WO2015143154A1 (en) | 2015-09-24 |
JP6606508B2 (ja) | 2019-11-13 |
KR20160138013A (ko) | 2016-12-02 |
MX369357B (es) | 2019-11-06 |
ES2800905T3 (es) | 2021-01-05 |
JP2017507993A (ja) | 2017-03-23 |
AU2015231208A1 (en) | 2016-10-06 |
US20170144990A1 (en) | 2017-05-25 |
MX2016012053A (es) | 2017-04-27 |
BR112016021282A8 (pt) | 2021-07-20 |
CN106459022B (zh) | 2019-08-02 |
AU2015231208B2 (en) | 2019-04-04 |
EP3119771B1 (en) | 2020-05-06 |
EP3119771A1 (en) | 2017-01-25 |
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Legal Events
Date | Code | Title | Description |
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B25D | Requested change of name of applicant approved |
Owner name: THE UNITED STATES OF AMERICA, AS REPRESENTED BY TH |
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |