BR112016019081A8 - cepa recombinante produtora de o-aminobenzoato e produção fermentativa de anilina a partir de recursos renováveis via ácido 2-aminobenzoico - Google Patents

cepa recombinante produtora de o-aminobenzoato e produção fermentativa de anilina a partir de recursos renováveis via ácido 2-aminobenzoico

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Publication number
BR112016019081A8
BR112016019081A8 BR112016019081A BR112016019081A BR112016019081A8 BR 112016019081 A8 BR112016019081 A8 BR 112016019081A8 BR 112016019081 A BR112016019081 A BR 112016019081A BR 112016019081 A BR112016019081 A BR 112016019081A BR 112016019081 A8 BR112016019081 A8 BR 112016019081A8
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BR
Brazil
Prior art keywords
aminobenzoate
aniline
converting
renewable resources
aminobenzoic acid
Prior art date
Application number
BR112016019081A
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English (en)
Other versions
BR112016019081A2 (pt
BR112016019081B1 (pt
Inventor
Gernot Jaeger
Jorgen Magnus
Amgad Salah Moussa
Günter Olf
Giulio Lolli
Swantje Behnken
Jung-Won Youn
Mohammad Yalfani
Georg Sprenger
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Covestro Deutschland Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Covestro Deutschland Ag filed Critical Covestro Deutschland Ag
Publication of BR112016019081A2 publication Critical patent/BR112016019081A2/pt
Publication of BR112016019081A8 publication Critical patent/BR112016019081A8/pt
Publication of BR112016019081B1 publication Critical patent/BR112016019081B1/pt

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    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
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    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1077Pentosyltransferases (2.4.2)
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/02Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
    • B01J20/10Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
    • B01J20/16Alumino-silicates
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    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/68Preparation of compounds containing amino groups bound to a carbon skeleton from amines, by reactions not involving amino groups, e.g. reduction of unsaturated amines, aromatisation, or substitution of the carbon skeleton
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    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/44Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
    • C07C211/45Monoamines
    • C07C211/46Aniline
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    • C12Y204/00Glycosyltransferases (2.4)
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    • C12Y504/99Intramolecular transferases (5.4) transferring other groups (5.4.99)
    • C12Y504/99005Chorismate mutase (5.4.99.5)

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  • Tropical Medicine & Parasitology (AREA)
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Abstract

cepa recombinante produtora de o-aminobenzoato e produção fermentativa de anilina a partir de recursos renováveis via ácido 2-aminobenzoico a invenção proporciona uma célula hospedeira microbiana recombinante capaz de converter, biologicamente, uma matéria-prima compreendendo um substrato de carbono fermentável em o-aminobenzoato (oab). a invenção proporciona ainda um método para a produção de anilina, compreendendo as etapas de: a) produção de o-aminobenzoato por fermentação de uma matéria-prima compreendendo, pelo menos, um substrato de carbono fermentável utilizando a célula hospedeira microbiana recombinante, capaz de converter biologicamente a dita matéria-prima compreendendo, pelo menos, um substrato de carbono fermentável em o-aminobenzoato, em que o dito o-aminobenzoato compreende o ânion antranilato, b) conversão do dito o-aminobenzoato a partir do dito ânion antranilato em ácido antranílico por protonação ácida, c) recuperação do dito ácido antranílico por precipitação ou por dissolução em um solvente orgânico e d) conversão do dito ácido antranílico em anilina por descarboxilação térmica em um solvente orgânico.
BR112016019081-5A 2014-02-20 2015-02-19 Célula hospedeira microbiana recombinante e método para a produção de anilina BR112016019081B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP14155936.9 2014-02-20
EP14155936 2014-02-20
EP14196432.0 2014-12-05
EP14196432 2014-12-05
PCT/EP2015/053526 WO2015124687A1 (en) 2014-02-20 2015-02-19 Recombinant strain producing o-aminobenzoate and fermentative production of aniline from renewable resources via 2-aminobenzoic acid

Publications (3)

Publication Number Publication Date
BR112016019081A2 BR112016019081A2 (pt) 2017-08-15
BR112016019081A8 true BR112016019081A8 (pt) 2021-07-13
BR112016019081B1 BR112016019081B1 (pt) 2023-05-30

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Also Published As

Publication number Publication date
BR112016019081A2 (pt) 2017-08-15
US10731187B2 (en) 2020-08-04
TW201546275A (zh) 2015-12-16
CA2939194A1 (en) 2015-08-27
WO2015124687A1 (en) 2015-08-27
KR20160123351A (ko) 2016-10-25
US20170152535A1 (en) 2017-06-01
CN106414714A (zh) 2017-02-15
KR102335689B1 (ko) 2021-12-07
EP3108015A1 (en) 2016-12-28

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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