BR112016016798A2 - - Google Patents

Info

Publication number
BR112016016798A2
BR112016016798A2 BR112016016798A BR112016016798A BR112016016798A2 BR 112016016798 A2 BR112016016798 A2 BR 112016016798A2 BR 112016016798 A BR112016016798 A BR 112016016798A BR 112016016798 A BR112016016798 A BR 112016016798A BR 112016016798 A2 BR112016016798 A2 BR 112016016798A2
Authority
BR
Brazil
Application number
BR112016016798A
Other languages
Portuguese (pt)
Other versions
BR112016016798B1 (pt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BR112016016798A2 publication Critical patent/BR112016016798A2/pt
Publication of BR112016016798B1 publication Critical patent/BR112016016798B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR112016016798-8A 2014-01-22 2015-01-21 Composto, composição farmacêutica, e, uso de um composto BR112016016798B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14152202.9 2014-01-22
EP14152202 2014-01-22
PCT/EP2015/051177 WO2015110491A2 (en) 2014-01-22 2015-01-21 Pyrazolo[1,5-a]pyrimidin-7-amine derivatives useful in therapy

Publications (2)

Publication Number Publication Date
BR112016016798A2 true BR112016016798A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2017-08-08
BR112016016798B1 BR112016016798B1 (pt) 2022-06-28

Family

ID=49989585

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016016798-8A BR112016016798B1 (pt) 2014-01-22 2015-01-21 Composto, composição farmacêutica, e, uso de um composto

Country Status (11)

Country Link
US (1) US9963455B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP3096762B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP6509238B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN106061975B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU2015208205B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BR (1) BR112016016798B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2935658C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2954126T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU2689788C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO2015110491A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA201605666B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2880327T3 (es) * 2017-04-05 2021-11-24 Curovir Ab Compuestos heteroaromáticos útiles en terapia
EP3740489A1 (en) * 2018-01-17 2020-11-25 GlaxoSmithKline Intellectual Property Development Limited Pi4kiiibeta inhibitors
CN108727386A (zh) * 2018-07-16 2018-11-02 广州医科大学 一种吡唑并嘧啶类化合物及其制备方法和用途
MX2020013039A (es) 2018-08-21 2021-02-26 Kyorin Seiyaku Kk Derivado de anillo heteroaromatico biciclico.
WO2020074160A1 (en) 2018-10-10 2020-04-16 Curovir Ab Condensed pyrimidine or pyridazine derivatives as antiviral agents
CA3115128A1 (en) * 2018-10-10 2020-04-16 Curovir Ab 2,6-dimethyl-n-((pyridin-4-yl)methyl)imidazo[1,2-b]pyridazin-8-amine and 2,5-dimethyl-n-[(pyridin-4-yl)methyl]pyrazolo[1,5-a]pyrimidin-7-amine derivatives for treating viral infections
CN109988172B (zh) * 2019-01-10 2020-09-29 石家庄学院 一种吡唑并[1,5-a]嘧啶类杂环化合物及衍生物的合成方法
EP4028131B1 (en) 2019-08-20 2023-11-22 Curovir Ab Heteroaromatic compounds useful in therapy
WO2024184442A1 (en) 2023-03-09 2024-09-12 Curovir Ab Compound and formulation for systemic therapy by oral transmucosal administration

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2585462B2 (ja) * 1989-10-25 1997-02-26 株式会社大塚製薬工場 ピラゾロ[1,5―a]ピリミジン誘導体
AU651986B2 (en) * 1991-04-22 1994-08-11 Otsuka Pharmaceutical Factory, Inc. Pyrazolo{1,5-a}pyrimidine derivative and anti-inflammatory containing the same
US6313124B1 (en) 1997-07-23 2001-11-06 Dupont Pharmaceuticals Company Tetrazine bicyclic compounds
KR20020047198A (ko) * 1999-09-30 2002-06-21 해피 페너 ; 해리 에이치. 페너 2세 특정 알킬렌 디아민-치환된피라졸로[1,5-a]-1,5-피리미딘 및피라졸로[1,5-a]-1,3,5-트리아진
DE60314623T2 (de) * 2002-05-10 2008-02-28 Smithkline Beecham Corp. Substituierte pyrazolopyrimidine
MY137843A (en) * 2002-09-04 2009-03-31 Schering Corp Pyrazolopyrimidines as cyclin dependent kinase inhibitors
US7601724B2 (en) * 2002-09-04 2009-10-13 Schering Corporation Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors
GB0519957D0 (en) * 2005-09-30 2005-11-09 Sb Pharmco Inc Chemical compound
WO2010086040A1 (en) 2009-01-29 2010-08-05 Biomarin Iga, Ltd. Pyrazolo-pyrimidines for treatment of duchenne muscular dystrophy
EP2539342B1 (en) * 2010-02-26 2015-04-15 Mitsubishi Tanabe Pharma Corporation Pyrazolopyrimidine compounds and their use as pde10 inhibitors
US8633198B1 (en) * 2011-09-20 2014-01-21 Nant Holdings Ip, Llc Small molecule inhibitors of influenza A RNA-dependent RNA polymerase

Also Published As

Publication number Publication date
BR112016016798B1 (pt) 2022-06-28
EP3096762C0 (en) 2023-06-28
EP3096762B1 (en) 2023-06-28
CN106061975B (zh) 2019-09-24
CN106061975A (zh) 2016-10-26
RU2016134130A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 2018-08-30
CA2935658A1 (en) 2015-07-30
AU2015208205A1 (en) 2016-08-18
ES2954126T3 (es) 2023-11-20
WO2015110491A3 (en) 2015-09-17
RU2689788C2 (ru) 2019-05-29
AU2015208205B2 (en) 2019-12-05
WO2015110491A2 (en) 2015-07-30
JP6509238B2 (ja) 2019-05-08
ZA201605666B (en) 2021-01-27
US9963455B2 (en) 2018-05-08
CA2935658C (en) 2023-02-21
RU2016134130A (ru) 2018-02-26
NZ722290A (en) 2021-08-27
EP3096762A2 (en) 2016-11-30
JP2017503830A (ja) 2017-02-02
US20160318937A1 (en) 2016-11-03

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: CUROVIR AB (SE)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 21/01/2015, OBSERVADAS AS CONDICOES LEGAIS