BR112016014236A2 - Agente profilático e terapêutico para o distúrbio do déficit de atenção/hiperatividade - Google Patents
Agente profilático e terapêutico para o distúrbio do déficit de atenção/hiperatividadeInfo
- Publication number
- BR112016014236A2 BR112016014236A2 BR112016014236A BR112016014236A BR112016014236A2 BR 112016014236 A2 BR112016014236 A2 BR 112016014236A2 BR 112016014236 A BR112016014236 A BR 112016014236A BR 112016014236 A BR112016014236 A BR 112016014236A BR 112016014236 A2 BR112016014236 A2 BR 112016014236A2
- Authority
- BR
- Brazil
- Prior art keywords
- hyperactivity disorder
- prophylactic
- drug
- therapeutic agent
- attention deficit
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
AGENTE PROFILÁTICO E TERAPÊUTICO PARA O DISTÚRBIO DO DÉFICIT DE ATENÇÃO/HIPERATIVIDADE. O 1-(benzofuran-2-il)-2-propilaminopentano ou um sal de adição de ácido farmacologicamente aceitável deste já é conhecido por apresentar uma excelente atividade/efeito como um medicamento an-tidepressivo, um medicamento psicotrópico, um medicamento para a doença anti-Parkinson e um medicamento para a doença anti-Alzheimer. No entanto, é verdadeiramente desconhecido que o composto é eficaz para a prevenção ou o tratamento do distúrbio de déficit de atenção/hiperatividade (ADHD). A presente invenção recentemente descobriu que o 1-(benzofuran-2-il)-2-propilaminopentano ou um sal de adição de ácido farmacologicamente aceitável deste é eficaz para a prevenção ou o tratamento do ADHD. Como um resultado, a presente invenção foi executada.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2013266498 | 2013-12-25 | ||
PCT/JP2014/083100 WO2015098591A1 (ja) | 2013-12-25 | 2014-12-15 | 注意欠如・多動性障害の予防および治療剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112016014236A2 true BR112016014236A2 (pt) | 2017-08-08 |
Family
ID=53478455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016014236A BR112016014236A2 (pt) | 2013-12-25 | 2014-12-15 | Agente profilático e terapêutico para o distúrbio do déficit de atenção/hiperatividade |
Country Status (14)
Country | Link |
---|---|
US (1) | US9782383B2 (pt) |
EP (1) | EP3087984B1 (pt) |
JP (1) | JP6518397B2 (pt) |
KR (1) | KR102280552B1 (pt) |
CN (1) | CN106163514B (pt) |
AU (1) | AU2014371437B2 (pt) |
BR (1) | BR112016014236A2 (pt) |
CA (1) | CA2932301A1 (pt) |
DK (1) | DK3087984T3 (pt) |
ES (1) | ES2864669T3 (pt) |
IL (1) | IL246872B (pt) |
RU (1) | RU2708694C2 (pt) |
SI (1) | SI3087984T1 (pt) |
WO (1) | WO2015098591A1 (pt) |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100572900B1 (ko) | 1997-08-07 | 2006-04-24 | 후지모토 쿄다이 가부시키가이샤 | 에틸아민 유도체 |
US6210705B1 (en) | 1997-12-15 | 2001-04-03 | Noven Pharmaceuticals, Nc. | Compositions and methods for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate |
JP4499208B2 (ja) * | 1998-10-29 | 2010-07-07 | 株式会社フジモト・コーポレーション | 新規な光学活性アミノペンタン誘導体 |
DE19934592C2 (de) | 1999-07-23 | 2003-10-23 | Benckiser Nv | Vorrichtung zur Aufnahme und dosierten Abgabe einer aktiven Zusammensetzung in eine Waschmaschine, einen Wäschetrockner oder eine Geschirrspülmaschine |
JP4953040B2 (ja) | 2001-09-19 | 2012-06-13 | 株式会社フジモト・コーポレーション | アポトーシス抑制剤 |
JP5030194B2 (ja) | 2004-11-25 | 2012-09-19 | 国立大学法人九州大学 | 薬物依存症治療剤 |
CA2612290C (en) | 2005-06-28 | 2014-10-07 | Fujimoto Co., Ltd. | Process for preparing optically active aminopentane derivative, intermediate and process for preparing intermediate |
WO2008095221A1 (en) * | 2007-02-07 | 2008-08-14 | Gosforth Centre (Holdings) Pty Ltd | Treatment of adhd |
JP2011529923A (ja) * | 2008-08-06 | 2011-12-15 | ゴスフォース センター(ホールディングス)プロプライエタリー リミテッド | 精神障害(psychiatricdisorder)を治療するための組成物および方法 |
SG175420A1 (en) * | 2009-05-12 | 2011-12-29 | Albany Molecular Res Inc | 7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof |
-
2014
- 2014-12-15 BR BR112016014236A patent/BR112016014236A2/pt not_active IP Right Cessation
- 2014-12-15 CA CA2932301A patent/CA2932301A1/en not_active Abandoned
- 2014-12-15 ES ES14875426T patent/ES2864669T3/es active Active
- 2014-12-15 DK DK14875426.0T patent/DK3087984T3/da active
- 2014-12-15 US US15/100,487 patent/US9782383B2/en active Active
- 2014-12-15 CN CN201480070808.5A patent/CN106163514B/zh not_active Expired - Fee Related
- 2014-12-15 KR KR1020167018583A patent/KR102280552B1/ko active IP Right Grant
- 2014-12-15 WO PCT/JP2014/083100 patent/WO2015098591A1/ja active Application Filing
- 2014-12-15 JP JP2015554751A patent/JP6518397B2/ja not_active Expired - Fee Related
- 2014-12-15 SI SI201431817T patent/SI3087984T1/sl unknown
- 2014-12-15 AU AU2014371437A patent/AU2014371437B2/en not_active Ceased
- 2014-12-15 EP EP14875426.0A patent/EP3087984B1/en active Active
- 2014-12-15 RU RU2016129912A patent/RU2708694C2/ru active
-
2016
- 2016-07-21 IL IL246872A patent/IL246872B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
IL246872B (en) | 2021-03-25 |
JPWO2015098591A1 (ja) | 2017-03-23 |
JP6518397B2 (ja) | 2019-05-22 |
SI3087984T1 (sl) | 2021-08-31 |
RU2708694C2 (ru) | 2019-12-11 |
WO2015098591A1 (ja) | 2015-07-02 |
EP3087984A1 (en) | 2016-11-02 |
EP3087984A4 (en) | 2017-08-23 |
KR20160096184A (ko) | 2016-08-12 |
CN106163514B (zh) | 2019-07-19 |
RU2016129912A (ru) | 2018-01-30 |
DK3087984T3 (da) | 2021-06-14 |
EP3087984B1 (en) | 2021-04-07 |
US9782383B2 (en) | 2017-10-10 |
AU2014371437B2 (en) | 2020-01-30 |
US20160296495A1 (en) | 2016-10-13 |
ES2864669T3 (es) | 2021-10-14 |
RU2016129912A3 (pt) | 2018-07-06 |
CA2932301A1 (en) | 2015-07-02 |
AU2014371437A1 (en) | 2016-06-16 |
CN106163514A (zh) | 2016-11-23 |
IL246872A0 (en) | 2016-09-29 |
KR102280552B1 (ko) | 2021-07-26 |
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE. |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2701 DE 11-10-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |