BR112016012701A2 - peptídeos recentemente identificados para uso na indução de tolerância oral em mamíferos jovens - Google Patents

peptídeos recentemente identificados para uso na indução de tolerância oral em mamíferos jovens

Info

Publication number
BR112016012701A2
BR112016012701A2 BR112016012701A BR112016012701A BR112016012701A2 BR 112016012701 A2 BR112016012701 A2 BR 112016012701A2 BR 112016012701 A BR112016012701 A BR 112016012701A BR 112016012701 A BR112016012701 A BR 112016012701A BR 112016012701 A2 BR112016012701 A2 BR 112016012701A2
Authority
BR
Brazil
Prior art keywords
milk
peptides
cow
oral tolerance
lactoglobulin
Prior art date
Application number
BR112016012701A
Other languages
English (en)
Other versions
BR112016012701B1 (pt
Inventor
Panchaud Alexandre
Blanchard Carine
Nutten Sophie
Original Assignee
Nestec Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nestec Sa filed Critical Nestec Sa
Publication of BR112016012701A2 publication Critical patent/BR112016012701A2/pt
Publication of BR112016012701B1 publication Critical patent/BR112016012701B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/733—Fructosans, e.g. inulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/736—Glucomannans or galactomannans, e.g. locust bean gum, guar gum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745—Bifidobacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/577—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 tolerising response

Abstract

a presente invenção se refere a peptídeos identificados recentemente que são capazes de induzir tolerância ao leite de vaca, especialmente à ß-lactoglobulina. os peptídeos podem ser administra-dos a mamíferos, especialmente a bebês que estão em risco de alergia a proteínas do leite de vaca, para induzir tolerância oral ao leite de vaca; eles também podem ser administrados a crianças e adultos que são alérgicos ao leite de vaca para permitir que a "dessensibilização" a proteínas alergênicas do leite, especialmente a ß-lactoglobulina, ocorra. os peptídeos podem também ser usados para induzir tolerância ao leite de cabra e búfala, especialmente à ß-lactoglobulina. os peptídeos são capazes de modular a resposta imunológica de mamíferos aos alérgenos.
BR112016012701-3A 2013-12-16 2013-12-16 Combinação de peptídeos para uso na indução de tolerância oral em mamíferos jovens, e composição BR112016012701B1 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2013/076643 WO2015090347A1 (en) 2013-12-16 2013-12-16 Newly identified peptides for use in the induction of oral tolerance in young mammals

Publications (2)

Publication Number Publication Date
BR112016012701A2 true BR112016012701A2 (pt) 2017-09-26
BR112016012701B1 BR112016012701B1 (pt) 2022-11-16

Family

ID=49841652

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016012701-3A BR112016012701B1 (pt) 2013-12-16 2013-12-16 Combinação de peptídeos para uso na indução de tolerância oral em mamíferos jovens, e composição

Country Status (13)

Country Link
US (1) US10092633B2 (pt)
EP (1) EP3082842B1 (pt)
CN (3) CN117224652A (pt)
AU (1) AU2013407963B2 (pt)
BR (1) BR112016012701B1 (pt)
ES (1) ES2918577T3 (pt)
MX (1) MX2016007714A (pt)
MY (1) MY186968A (pt)
PH (1) PH12016501114B1 (pt)
PT (1) PT3082842T (pt)
RU (1) RU2668155C1 (pt)
WO (1) WO2015090347A1 (pt)
ZA (1) ZA201604931B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016148562A1 (en) * 2015-03-18 2016-09-22 N.V. Nutricia Method for inducing oral tolerance via administration of beta-lactoglobulin derived peptide in combination with probiotic
ES2807831T3 (es) 2015-06-12 2021-02-24 Nestle Sa Combinacion de peptidos tolerogenos con TFG-â para inducir y mantener la tolerancia oral en mamiferos jovenes
CN108314704B (zh) * 2018-01-25 2020-03-17 海普诺凯营养品有限公司 一种羊乳清蛋白免疫调节肽、其制备方法及其应用
WO2019212330A1 (en) 2018-04-30 2019-11-07 N.V. Nutricia Formula with a specific beta-lactoglobulin peptide
WO2019212329A1 (en) 2018-04-30 2019-11-07 N.V. Nutricia Formula with specific beta-lactoglobulin peptides
AU2019473379A1 (en) 2019-11-07 2022-04-14 N.V. Nutricia Extensive whey protein hydrolysate with tolerogenic peptides
CN113311155B (zh) * 2021-04-09 2022-11-29 深圳市计量质量检测研究院（国家高新技术计量站、国家数字电子产品质量监督检验中心） 一种牛乳蛋白和水牛乳蛋白二联检测卡的制备方法及应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1200416A (en) 1983-05-13 1986-02-11 Societe Des Produits Nestle S.A. Food process
EP0321603A1 (fr) 1987-12-23 1989-06-28 Societe Des Produits Nestle S.A. Procédé de préparation d'un hydrolysat de protéines de lactosérum et d'un aliment hypoallergéniques
GB9312369D0 (en) 1993-06-16 1993-07-28 Sandoz Nutrition Ltd Organic compounds
US5620348A (en) 1995-05-12 1997-04-15 Timex Corporation Method of manufacturing electroluminescent lamps having surface designs and lamps produced thereby
EP0880902A1 (fr) 1997-05-27 1998-12-02 Nestlé Produkte AG Procédé de traitement d'une matiére première lactosérique
MY129566A (en) 1999-01-19 2007-04-30 Nestle Sa A hypoallergenic composition containing tolerogenic peptides inducing oral tolerance
JP3441411B2 (ja) * 1999-10-12 2003-09-02 明治乳業株式会社 コレステロール低減化ペプチド
RU2192884C2 (ru) 2000-11-09 2002-11-20 Государственное учреждение Научно-исследовательский институт клинической иммунологии СО РАМН Вакцина для стимуляции противоопухолевого иммунитета
US20040007700A1 (en) 2002-07-01 2004-01-15 Hazel Danny G. Non-snagging protective guide for fish tapes
US20060286208A1 (en) * 2005-06-01 2006-12-21 Nagendra Rangavajla Methods for producing protein partial hydrolysates and infant formulas containing the same
WO2007004876A2 (en) * 2005-06-30 2007-01-11 Campina Nederland Holding B.V. Peptides inhibiting angiotensin-converting enzyme
ES2342625T5 (es) 2006-02-10 2020-05-07 Nestle Sa Mezcla de oligosacáridos
ES2524067T3 (es) 2009-12-04 2014-12-03 Mjn U.S. Holdings Llc Formulación nutricional que comprende un hidrolizado que contiene péptidos de leche de vaca y/o péptidos derivados del mismo para la inducción de tolerancia
WO2011150949A1 (en) * 2010-06-04 2011-12-08 N.V. Nutricia Non-digestible oligosaccharides for oral induction of tolerance against dietary proteins
WO2012075570A1 (en) * 2010-12-09 2012-06-14 Mcgill University Bioactive peptides and proteins containing bioactive peptides, their uses and processes for making the same
US20130344042A1 (en) * 2012-06-20 2013-12-26 Gretchen Tanbonliong Dietary management of celiac disease and food allergy

Also Published As

Publication number Publication date
PH12016501114A1 (en) 2016-07-11
EP3082842A1 (en) 2016-10-26
BR112016012701B1 (pt) 2022-11-16
CN117224652A (zh) 2023-12-15
WO2015090347A1 (en) 2015-06-25
ES2918577T3 (es) 2022-07-19
MX2016007714A (es) 2017-02-28
PT3082842T (pt) 2022-06-17
PH12016501114B1 (en) 2016-07-11
RU2016128923A (ru) 2018-01-23
RU2668155C1 (ru) 2018-09-26
US10092633B2 (en) 2018-10-09
CN105828830A (zh) 2016-08-03
US20160375114A1 (en) 2016-12-29
ZA201604931B (en) 2020-01-29
AU2013407963B2 (en) 2019-10-10
MY186968A (en) 2021-08-26
CN117018181A (zh) 2023-11-10
EP3082842B1 (en) 2022-04-13

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B25A Requested transfer of rights approved

Owner name: SOCIETE DES PRODUITS NESTLE S.A. (CH)

B350 Update of information on the portal [chapter 15.35 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 16/12/2013, OBSERVADAS AS CONDICOES LEGAIS