BR112016012248A2 - método de tratamento de nefropatia - Google Patents

método de tratamento de nefropatia

Info

Publication number
BR112016012248A2
BR112016012248A2 BR112016012248A BR112016012248A BR112016012248A2 BR 112016012248 A2 BR112016012248 A2 BR 112016012248A2 BR 112016012248 A BR112016012248 A BR 112016012248A BR 112016012248 A BR112016012248 A BR 112016012248A BR 112016012248 A2 BR112016012248 A2 BR 112016012248A2
Authority
BR
Brazil
Prior art keywords
treatment method
nephropathy treatment
nephropathy
diabetic nephropathy
individual
Prior art date
Application number
BR112016012248A
Other languages
English (en)
Inventor
Falkevall Annelie
Mehlem Annika
Eriksson Ulf
Original Assignee
B Creative Sweden Ab
Csl Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2013904595A external-priority patent/AU2013904595A0/en
Application filed by B Creative Sweden Ab, Csl Ltd filed Critical B Creative Sweden Ab
Publication of BR112016012248A2 publication Critical patent/BR112016012248A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/30—Special therapeutic applications

Abstract

a presente invenção proporciona um método de tratamento de nefropatia diabética em um indivíduo acometido de nefropatia diabética, o método compreendendo a administração ao indivíduo de um composto que inibe a sinalização de vegf-b.
BR112016012248A 2013-11-28 2014-11-28 método de tratamento de nefropatia BR112016012248A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2013904595A AU2013904595A0 (en) 2013-11-28 Method of treating nephropathy
PCT/AU2014/050387 WO2015077845A1 (en) 2013-11-28 2014-11-28 Method of treating nephropathy

Publications (1)

Publication Number Publication Date
BR112016012248A2 true BR112016012248A2 (pt) 2017-10-17

Family

ID=53198116

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016012248A BR112016012248A2 (pt) 2013-11-28 2014-11-28 método de tratamento de nefropatia

Country Status (14)

Country Link
US (3) US9803008B2 (pt)
EP (2) EP3530286A1 (pt)
JP (2) JP6612246B2 (pt)
KR (1) KR102339724B1 (pt)
CN (1) CN105873608A (pt)
AU (1) AU2014354588B2 (pt)
BR (1) BR112016012248A2 (pt)
CA (1) CA2931357C (pt)
DK (1) DK3074038T3 (pt)
ES (1) ES2711882T3 (pt)
PL (1) PL3074038T3 (pt)
RU (1) RU2718054C2 (pt)
TR (1) TR201900665T4 (pt)
WO (1) WO2015077845A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2718054C2 (ru) 2013-11-28 2020-03-30 СиЭсЭл ЛИМИТЕД Способ лечения нефропатии
US10336821B2 (en) 2014-11-17 2019-07-02 Csl Limited Method of treating stroke by administering a compound that inhibits VEGF-B signaling in combination with a thrombolytic agent
RU2651895C2 (ru) * 2015-12-01 2018-04-24 Алексей Николаевич Вачёв Способ прогнозирования клинического эффекта после операции реваскуляризации почек у больных с ишемической нефропатией
US20190119369A1 (en) * 2016-04-21 2019-04-25 Csl Limited Method of treating or preventing liver conditions
RU2754509C1 (ru) * 2020-12-21 2021-09-02 федеральное государственное бюджетное образовательное учреждение высшего образования "Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения Российской Федерации Способ лечения первичной мембранозной нефропатии с нефротическим синдромом и повышенным уровнем анти-plar2

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Also Published As

Publication number Publication date
US20180086824A1 (en) 2018-03-29
US20200010541A1 (en) 2020-01-09
RU2718054C2 (ru) 2020-03-30
US9803008B2 (en) 2017-10-31
KR20160083121A (ko) 2016-07-11
EP3074038A1 (en) 2016-10-05
TR201900665T4 (tr) 2019-02-21
WO2015077845A1 (en) 2015-06-04
US10407498B2 (en) 2019-09-10
US11261243B2 (en) 2022-03-01
JP6802342B2 (ja) 2020-12-16
JP2016540047A (ja) 2016-12-22
CN105873608A (zh) 2016-08-17
JP6612246B2 (ja) 2019-11-27
CA2931357A1 (en) 2015-06-04
EP3074038B1 (en) 2019-01-02
PL3074038T3 (pl) 2019-08-30
ES2711882T3 (es) 2019-05-08
AU2014354588B2 (en) 2020-07-02
AU2014354588A1 (en) 2016-06-02
KR102339724B1 (ko) 2021-12-17
US20170037119A1 (en) 2017-02-09
DK3074038T3 (en) 2019-03-11
JP2020029459A (ja) 2020-02-27
RU2016125513A (ru) 2018-01-10
EP3074038A4 (en) 2017-08-02
CA2931357C (en) 2022-07-12
EP3530286A1 (en) 2019-08-28

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