ECSP16024798A - Nuevo compuesto para el tratamiento de hipoglicemia severa - Google Patents

Nuevo compuesto para el tratamiento de hipoglicemia severa

Info

Publication number
ECSP16024798A
ECSP16024798A ECIEPI201624798A ECPI201624798A ECSP16024798A EC SP16024798 A ECSP16024798 A EC SP16024798A EC IEPI201624798 A ECIEPI201624798 A EC IEPI201624798A EC PI201624798 A ECPI201624798 A EC PI201624798A EC SP16024798 A ECSP16024798 A EC SP16024798A
Authority
EC
Ecuador
Prior art keywords
treatment
new compound
severe hypoglycemia
hypoglycemia
severe
Prior art date
Application number
ECIEPI201624798A
Other languages
English (en)
Inventor
Jorge Alsina-Fernandez
Robert Chadwick Cummins
Lili Guo
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ECSP16024798A publication Critical patent/ECSP16024798A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Removal Of Specific Substances (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere a un nuevo compuesto útil en el tratamiento de hipoglicemia.
ECIEPI201624798A 2013-12-18 2016-06-16 Nuevo compuesto para el tratamiento de hipoglicemia severa ECSP16024798A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361917597P 2013-12-18 2013-12-18

Publications (1)

Publication Number Publication Date
ECSP16024798A true ECSP16024798A (es) 2017-05-31

Family

ID=52278802

Family Applications (1)

Application Number Title Priority Date Filing Date
ECIEPI201624798A ECSP16024798A (es) 2013-12-18 2016-06-16 Nuevo compuesto para el tratamiento de hipoglicemia severa

Country Status (27)

Country Link
US (1) US9695225B2 (es)
EP (1) EP3083668A1 (es)
JP (1) JP2017509584A (es)
KR (1) KR20160075825A (es)
CN (1) CN105814076A (es)
AP (1) AP2016009242A0 (es)
AR (1) AR098614A1 (es)
AU (1) AU2014366424B2 (es)
BR (1) BR112016012067A2 (es)
CA (1) CA2928985A1 (es)
CL (1) CL2016001472A1 (es)
CR (1) CR20160226A (es)
DO (1) DOP2016000096A (es)
EA (1) EA201690914A1 (es)
EC (1) ECSP16024798A (es)
GT (1) GT201600117A (es)
HK (1) HK1224304A1 (es)
IL (1) IL245400A0 (es)
MA (1) MA39109B1 (es)
MX (1) MX2016007982A (es)
NZ (1) NZ719463A (es)
PE (1) PE20160848A1 (es)
PH (1) PH12016501182A1 (es)
SG (1) SG11201604154SA (es)
TN (1) TN2016000181A1 (es)
TW (1) TW201609127A (es)
WO (1) WO2015094875A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI622596B (zh) 2015-10-26 2018-05-01 美國禮來大藥廠 升糖素受體促效劑
WO2019140024A1 (en) 2018-01-12 2019-07-18 Eli Lilly And Company Combination therapy
CN113396156A (zh) 2019-02-05 2021-09-14 伊莱利利公司 胰高血糖素类似物激动剂及其使用方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1891105E (pt) 2005-06-13 2012-06-27 Imp Innovations Ltd Análogos de oxintomodulina e seus efeitos sobre o comportamento da alimentação
ES2628063T3 (es) 2007-01-05 2017-08-01 Indiana University Research And Technology Corporation Análogos de glucagón que muestran una mayor solubilidad en tampones de pH fisiológicos
US20090098130A1 (en) * 2007-01-05 2009-04-16 Bradshaw Curt W Glucagon-like protein-1 receptor (glp-1r) agonist compounds
CL2009001425A1 (es) 2008-06-17 2010-04-30 Univ Indiana Res & Tech Corp Analogos de glucagon con un aminoacido aromatico grande que carece de cadena lateral de imidazol que le confiere actividad agonista del receptor gip; composiciones farmaceutica; kit que los contiene y uso para reducir el aumento de peso, tratar la diabetes o inducir paralisis del tracto intestinal.
CA2727161A1 (en) * 2008-06-17 2009-12-23 Indiana University Research And Technology Corporation Glucagon analogs exhibiting enhanced solubility and stability physiological ph buffers
IN2012DN00377A (es) 2009-06-16 2015-08-21 Univ Indiana Res & Tech Corp
US20120148586A1 (en) * 2009-08-27 2012-06-14 Joyce Ching Tsu Chou Glucagon-like protein-1 receptor (glp-1r) agonists for treating autoimmune disorders
US8703701B2 (en) 2009-12-18 2014-04-22 Indiana University Research And Technology Corporation Glucagon/GLP-1 receptor co-agonists
MX2012013005A (es) * 2010-05-13 2013-02-26 Univ Indiana Res & Tech Corp Peptidos de la superfamilia de glucagon que presentan actividad del receptor acoplado a proteinas g.
BR112013015389A2 (pt) 2010-12-22 2016-11-22 Univ Indiana Res & Tech Corp análogo de glucagon exibindo atividade de receptor gip
ES2692187T3 (es) * 2011-06-10 2018-11-30 Hanmi Science Co., Ltd. Nuevos derivados de oxintomodulina y composición farmacéutica para el tratamiento de obesidad que lo comprende
MX2013015168A (es) 2011-06-22 2014-03-31 Univ Indiana Res & Tech Corp Co-agonista del receptor de glucagon/glp-1.
WO2013004983A1 (en) * 2011-07-04 2013-01-10 Imperial Innovations Limited Novel compounds and their effects on feeding behaviour
KR20150023013A (ko) * 2012-06-21 2015-03-04 인디애나 유니버시티 리서치 앤드 테크놀로지 코퍼레이션 수용체 활성을 나타내는 글루카곤 유사체

Also Published As

Publication number Publication date
CN105814076A (zh) 2016-07-27
AU2014366424B2 (en) 2017-02-16
JP2017509584A (ja) 2017-04-06
CR20160226A (es) 2016-07-12
PH12016501182A1 (en) 2016-07-25
HK1224304A1 (zh) 2017-08-18
IL245400A0 (en) 2016-06-30
MX2016007982A (es) 2016-09-09
SG11201604154SA (en) 2016-07-28
DOP2016000096A (es) 2016-08-15
CA2928985A1 (en) 2015-06-25
TN2016000181A1 (en) 2017-10-06
CL2016001472A1 (es) 2017-03-10
NZ719463A (en) 2017-09-29
AP2016009242A0 (en) 2016-06-30
MA39109B1 (fr) 2018-04-30
AR098614A1 (es) 2016-06-01
PE20160848A1 (es) 2016-09-10
BR112016012067A2 (pt) 2017-09-26
US20160311881A1 (en) 2016-10-27
WO2015094875A1 (en) 2015-06-25
TW201609127A (zh) 2016-03-16
GT201600117A (es) 2017-07-06
AU2014366424A1 (en) 2016-05-19
EA201690914A1 (ru) 2016-09-30
KR20160075825A (ko) 2016-06-29
MA39109A1 (fr) 2017-09-29
EP3083668A1 (en) 2016-10-26
US9695225B2 (en) 2017-07-04

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