BR112016009089A2 - Microrganismos para a produção de o-succinil-homosserina e método para produção de o-succinil-homosserina utilizando os mesmos - Google Patents

Microrganismos para a produção de o-succinil-homosserina e método para produção de o-succinil-homosserina utilizando os mesmos

Info

Publication number
BR112016009089A2
BR112016009089A2 BR112016009089A BR112016009089A BR112016009089A2 BR 112016009089 A2 BR112016009089 A2 BR 112016009089A2 BR 112016009089 A BR112016009089 A BR 112016009089A BR 112016009089 A BR112016009089 A BR 112016009089A BR 112016009089 A2 BR112016009089 A2 BR 112016009089A2
Authority
BR
Brazil
Prior art keywords
succinyl
homoserin
production
organisms
micro
Prior art date
Application number
BR112016009089A
Other languages
English (en)
Other versions
BR112016009089B1 (pt
Inventor
Il Seo Chang
Young Kim So
Uk Shin Yong
Ho Na Kwang
Won Um Hye
Kyung Heo In
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of BR112016009089A2 publication Critical patent/BR112016009089A2/pt
Publication of BR112016009089B1 publication Critical patent/BR112016009089B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01046—Homoserine O-succinyltransferase (2.3.1.46)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

MICRORGANISMOS PARA A PRODUÇÃO DE O-SUCCINIL-HOMOSSERINA E MÉTODO PARA PRODUÇÃO DE O-SUCCINIL-HOMOSSERINA UTILIZANDO OS MESMOS. A presente invenção se refere a um polipeptídeo que é resistente à inibição por feedback por metionina e tem uma atividade da homosserina O-succiniltransferase, um microrganismo para a produção de O-succinil-homosserina que expressa o polipeptídeo e um método para produzir O-succinil-homosserina utilizando o mesmo.
BR112016009089-6A 2013-10-23 2014-10-22 Microrganismos para a produção de o-succinil-homosserina e método para produção de o-succinil-homosserina utilizando os mesmos BR112016009089B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2013-0126602 2013-10-23
KR1020130126602A KR101565213B1 (ko) 2013-10-23 2013-10-23 Ｏ-숙시닐호모세린 생산 미생물 및 이를 이용한 ｏ-숙시닐호모세린의 생산방법
PCT/KR2014/009970 WO2015060649A1 (ko) 2013-10-23 2014-10-22 O-숙시닐호모세린 생산 미생물 및 이를 이용한 o-숙시닐호모세린의 생산방법

Publications (2)

Publication Number Publication Date
BR112016009089A2 true BR112016009089A2 (pt) 2017-09-19
BR112016009089B1 BR112016009089B1 (pt) 2023-03-28

Family

ID=52993174

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016009089-6A BR112016009089B1 (pt) 2013-10-23 2014-10-22 Microrganismos para a produção de o-succinil-homosserina e método para produção de o-succinil-homosserina utilizando os mesmos

Country Status (11)

Country Link
US (1) US10221434B2 (pt)
EP (1) EP3061814B1 (pt)
JP (1) JP6388935B2 (pt)
KR (1) KR101565213B1 (pt)
CN (1) CN105829529B (pt)
BR (1) BR112016009089B1 (pt)
ES (1) ES2717939T3 (pt)
MY (2) MY193748A (pt)
PL (1) PL3061814T3 (pt)
RU (2) RU2756104C2 (pt)
WO (1) WO2015060649A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102112208B1 (ko) * 2017-06-30 2020-05-19 씨제이제일제당 주식회사 신규한 o-숙시닐 호모세린 트랜스퍼라제 변이체 및 이를 이용한 o-숙시닐 호모세린의 제조방법
RU2747493C1 (ru) * 2017-06-30 2021-05-05 СиДжей ЧеилДжеданг Корпорейшн Новый вариант О-сукцинилгомосеринтрансферазы и способ получения О-сукцинилгомосерина с использованием этого варианта
CN108949661B (zh) * 2018-07-27 2021-06-08 浙江工业大学 一种产o-琥珀酰-l-高丝氨酸重组大肠杆菌及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10305774A1 (de) * 2003-02-06 2004-08-26 Consortium für elektrochemische Industrie GmbH Verfahren zur fermentativen Herstellung von L-Methionin
US7029893B2 (en) * 2003-02-28 2006-04-18 Ajinomoto Co., Inc. Polynucleotides encoding polypeptides involved in amino acid biosynthesis in methylophilus methylotrophus
KR100576342B1 (ko) 2004-02-05 2006-05-03 씨제이 주식회사 ｇａｌＲ 유전자가 불활성화된 Ｌ-쓰레오닌 생성 미생물,그를 제조하는 방법 및 상기 미생물을 이용한Ｌ-쓰레오닌의 제조방법
KR100620092B1 (ko) 2004-12-16 2006-09-08 씨제이 주식회사 코리네박테리움 속 세포로부터 유래된 신규한 프로모터서열, 그를 포함하는 발현 카세트 및 벡터, 상기 벡터를포함하는 숙주 세포 및 그를 이용하여 유전자를 발현하는방법
KR100905381B1 (ko) * 2006-07-28 2009-06-30 씨제이제일제당 (주) Ｌ-메치오닌 전구체 생산 균주 및 상기 ｌ-메치오닌전구체로부터의 ｌ-메치오닌 및 유기산의 생산방법
CN101688190B (zh) * 2007-04-11 2014-06-04 Cj第一制糖株式会社 组合物及甲硫氨酸的生产方法
US7851180B2 (en) * 2008-04-04 2010-12-14 Cj Cheiljedang Corporation Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism
KR101136248B1 (ko) * 2008-04-04 2012-04-20 씨제이제일제당 (주) Ｌ-메치오닌 전구체 생산 균주 및 이를 이용한 ｌ-메치오닌 전구체의 생산 방법
US8283152B2 (en) * 2009-08-28 2012-10-09 Cj Cheiljedang Corporation Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
US8609396B2 (en) * 2009-08-28 2013-12-17 Cj Cheiljedang Corporation Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
RU2557411C2 (ru) * 2010-12-21 2015-07-20 СиДжей ЧЕИЛДЗЕДАНГ КОРПОРЕЙШН Модифицированный полипептид, обдадающий гомосеринацетилтрансферазной активностью, и экспрессирующий его микроорганизм

Also Published As

Publication number Publication date
EP3061814B1 (en) 2019-02-27
ES2717939T3 (es) 2019-06-26
PL3061814T3 (pl) 2019-08-30
JP6388935B2 (ja) 2018-09-12
BR112016009089B1 (pt) 2023-03-28
US20160304920A1 (en) 2016-10-20
EP3061814A1 (en) 2016-08-31
RU2018121333A3 (pt) 2020-12-15
RU2016116154A (ru) 2017-11-28
CN105829529A (zh) 2016-08-03
RU2662654C2 (ru) 2018-07-26
MY195206A (en) 2023-01-11
KR20150047665A (ko) 2015-05-06
KR101565213B1 (ko) 2015-11-03
JP2016533730A (ja) 2016-11-04
MY193748A (en) 2022-10-27
RU2756104C2 (ru) 2021-09-28
RU2018121333A (ru) 2019-03-05
WO2015060649A1 (ko) 2015-04-30
EP3061814A4 (en) 2017-06-07
US10221434B2 (en) 2019-03-05
CN105829529B (zh) 2019-11-08

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Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 22/10/2014, OBSERVADAS AS CONDICOES LEGAIS