BR112016007099A2 - material de regeneração de osso e método para a sua produção - Google Patents
material de regeneração de osso e método para a sua produçãoInfo
- Publication number
- BR112016007099A2 BR112016007099A2 BR112016007099A BR112016007099A BR112016007099A2 BR 112016007099 A2 BR112016007099 A2 BR 112016007099A2 BR 112016007099 A BR112016007099 A BR 112016007099A BR 112016007099 A BR112016007099 A BR 112016007099A BR 112016007099 A2 BR112016007099 A2 BR 112016007099A2
- Authority
- BR
- Brazil
- Prior art keywords
- hydroxyapatite
- production
- phase
- liquid
- bone regeneration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
- A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
- A61L27/3645—Connective tissue
- A61L27/365—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Public Health (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Materials For Medical Uses (AREA)
Abstract
resumo da patente de invenção para: "material de regeneração de osso e método para a sua produção". a invenção diz respeito a um método que inclui: colocar um material ósseo, que contém hidroxiapatite e substâncias orgânicas, em contato com um líquido de extração que dá origem a uma primeira fase líquida, que contém as referidas substâncias orgânicas e, possivelmente, impurezas extraídas a partir do referido material ósseo, e uma segunda fase de hidroxiapatite sólida, que contém a referida hidroxiapatite; e separar a referida fase líquida e a referida fase de hidroxiapatite sólida. o referido líquido de extração é uma solução aquosa de extração que é levada a uma temperatura compreendida entre 150ºc e 300ºc e a uma pressão compreendida entre 150 kpa e 350 kpa.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE2013/0660 | 2013-10-03 | ||
BE2013/0660A BE1023728B1 (fr) | 2013-10-03 | 2013-10-03 | Materiau de regeneration osseuse et son procede de fabrication |
PCT/EP2014/071157 WO2015049336A1 (fr) | 2013-10-03 | 2014-10-02 | Materiau de regeneration osseuse et son procede de fabrication |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112016007099A2 true BR112016007099A2 (pt) | 2017-08-01 |
BR112016007099B1 BR112016007099B1 (pt) | 2020-12-08 |
Family
ID=49752883
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016007099-2A BR112016007099B1 (pt) | 2013-10-03 | 2014-10-02 | material de regeneração de osso e método para a sua produção |
Country Status (12)
Country | Link |
---|---|
US (1) | US10251974B2 (pt) |
EP (1) | EP3052154B1 (pt) |
JP (1) | JP6457503B2 (pt) |
KR (1) | KR102301329B1 (pt) |
CN (1) | CN105722536B (pt) |
AU (1) | AU2014331096B2 (pt) |
BE (1) | BE1023728B1 (pt) |
BR (1) | BR112016007099B1 (pt) |
CA (1) | CA2925102C (pt) |
ES (1) | ES2911776T3 (pt) |
RU (1) | RU2674444C2 (pt) |
WO (1) | WO2015049336A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101886413B1 (ko) * | 2016-03-16 | 2018-08-10 | 주식회사 엘앤씨바이오 | 히알루론산에 기반한 연조직 충진 조성물의 제조 방법 |
CN106018019A (zh) * | 2016-05-13 | 2016-10-12 | 北京九州柏林生物科技有限公司 | 复合式生物组织样本制备脱水液 |
US20200121827A1 (en) | 2017-01-16 | 2020-04-23 | Wishbone | Bone regeneration material |
CN106822998A (zh) * | 2017-02-22 | 2017-06-13 | 昆明医科大学 | 促进颌骨再生材料及应用 |
BE1028336B1 (fr) | 2020-05-22 | 2021-12-21 | Wishbone | Dispositif de recouvrement agence pour favoriser une regeneration osseuse |
BE1030086B1 (fr) | 2021-12-23 | 2023-07-26 | Wishbone | Matériau de régénération osseuse |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8813033D0 (en) * | 1988-06-02 | 1988-07-06 | Geistlich Soehne Ag | Chemical compound |
IT1268641B1 (it) * | 1994-10-24 | 1997-03-06 | Giuseppe Oliva | Inattivazione ed eliminazione di matrice organica da osso animale per xenotrapianti eterotopici. |
US6221109B1 (en) * | 1999-09-15 | 2001-04-24 | Ed. Geistlich Söhne AG fur Chemische Industrie | Method of protecting spinal area |
US6837907B2 (en) * | 2001-03-28 | 2005-01-04 | Lifenet | Method for debriding bone, and bone debrided thereby |
US8563489B2 (en) * | 2007-12-12 | 2013-10-22 | Chemtura Corporation | Alkylated 1,3-benzenediamine compounds and methods for producing same |
KR101193386B1 (ko) * | 2009-10-01 | 2012-10-23 | 부경대학교 산학협력단 | 참치 뼈 유래 수산화인회의 제조방법 |
-
2013
- 2013-10-03 BE BE2013/0660A patent/BE1023728B1/fr active
-
2014
- 2014-10-02 WO PCT/EP2014/071157 patent/WO2015049336A1/fr active Application Filing
- 2014-10-02 RU RU2016114149A patent/RU2674444C2/ru active
- 2014-10-02 EP EP14780841.4A patent/EP3052154B1/fr active Active
- 2014-10-02 US US15/026,217 patent/US10251974B2/en active Active
- 2014-10-02 ES ES14780841T patent/ES2911776T3/es active Active
- 2014-10-02 CA CA2925102A patent/CA2925102C/fr active Active
- 2014-10-02 KR KR1020167009660A patent/KR102301329B1/ko active IP Right Grant
- 2014-10-02 BR BR112016007099-2A patent/BR112016007099B1/pt active IP Right Grant
- 2014-10-02 JP JP2016519351A patent/JP6457503B2/ja active Active
- 2014-10-02 AU AU2014331096A patent/AU2014331096B2/en active Active
- 2014-10-02 CN CN201480054144.3A patent/CN105722536B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
BR112016007099B1 (pt) | 2020-12-08 |
KR20160068785A (ko) | 2016-06-15 |
RU2016114149A (ru) | 2017-11-10 |
CN105722536A (zh) | 2016-06-29 |
JP2016533205A (ja) | 2016-10-27 |
EP3052154A1 (fr) | 2016-08-10 |
KR102301329B1 (ko) | 2021-09-14 |
CA2925102C (fr) | 2021-11-09 |
US10251974B2 (en) | 2019-04-09 |
US20160235885A1 (en) | 2016-08-18 |
WO2015049336A1 (fr) | 2015-04-09 |
ES2911776T3 (es) | 2022-05-20 |
EP3052154B1 (fr) | 2022-01-26 |
BE1023728B1 (fr) | 2017-06-30 |
CA2925102A1 (fr) | 2015-04-09 |
AU2014331096A1 (en) | 2016-04-28 |
JP6457503B2 (ja) | 2019-01-23 |
RU2016114149A3 (pt) | 2018-07-09 |
RU2674444C2 (ru) | 2018-12-10 |
CN105722536B (zh) | 2020-06-16 |
AU2014331096B2 (en) | 2018-05-31 |
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Legal Events
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B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 02/10/2014, OBSERVADAS AS CONDICOES LEGAIS. |