BR112016005413A2 - usos de pelo menos um mirna, kit, métodos de diagnóstico de câncer de mama e métodos para avaliação de risco de metástase - Google Patents

usos de pelo menos um mirna, kit, métodos de diagnóstico de câncer de mama e métodos para avaliação de risco de metástase

Info

Publication number
BR112016005413A2
BR112016005413A2 BR112016005413A BR112016005413A BR112016005413A2 BR 112016005413 A2 BR112016005413 A2 BR 112016005413A2 BR 112016005413 A BR112016005413 A BR 112016005413A BR 112016005413 A BR112016005413 A BR 112016005413A BR 112016005413 A2 BR112016005413 A2 BR 112016005413A2
Authority
BR
Brazil
Prior art keywords
methods
breast cancer
risk assessment
mirna
kit
Prior art date
Application number
BR112016005413A
Other languages
English (en)
Other versions
BR112016005413A8 (pt
Inventor
Longatto Filho Adhemar
Feijo Evangelista Adriane
Ludvik Filip Marino Augusto
Cesar Santejo Silveira Henrique
Maria Kerr Ligia
Maria Chiquitelli Marques Silveira Márcia
Aloisio Da Costa Vieira René
Macedo Taciane
Original Assignee
Fund Pio Xii
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fund Pio Xii filed Critical Fund Pio Xii
Publication of BR112016005413A2 publication Critical patent/BR112016005413A2/pt
Publication of BR112016005413A8 publication Critical patent/BR112016005413A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111—General methods applicable to biologically active non-coding nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C12N2310/141—MicroRNAs, miRNAs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/10—Applications; Uses in screening processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Hospice & Palliative Care (AREA)

Abstract

a presente invenção refere-se a novos usos de pelo menos um micrornas, como biomarcadores de câncer de mama e como biomarcadores de potencial metastático em câncer de mama. ainda, a presente invenção refere-se a kits que compreendem ditos biomarcadores e aos métodos de diagnóstico de câncer de mama e para avaliação de risco de metástase.
BR112016005413A 2013-09-11 2013-09-11 Usos de pelo menos um mirna, kit, métodos de diagnóstico de câncer de mama e métodos para avaliação de risco de metástase BR112016005413A8 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/BR2013/000357 WO2015035480A1 (pt) 2013-09-11 2013-09-11 USOS DE PELO MENOS UM miRNA, KIT, MÉTODOS DE DIAGNÓSTICO DE CÂNCER DE MAMA E MÉTODOS PARA AVALIAÇÃO DE RISCO DE METÁSTASE

Publications (2)

Publication Number Publication Date
BR112016005413A2 true BR112016005413A2 (pt) 2017-11-21
BR112016005413A8 BR112016005413A8 (pt) 2018-04-03

Family

ID=52664853

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016005413A BR112016005413A8 (pt) 2013-09-11 2013-09-11 Usos de pelo menos um mirna, kit, métodos de diagnóstico de câncer de mama e métodos para avaliação de risco de metástase

Country Status (2)

Country Link
BR (1) BR112016005413A8 (pt)
WO (1) WO2015035480A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110184351A (zh) * 2019-05-29 2019-08-30 南通普惠精准医疗科技有限公司 检测试剂盒的应用
WO2023170659A1 (en) 2022-03-11 2023-09-14 Consejo Nacional De Investigaciones Cientificas Y Tecnicas (Conicet) Breast cancer diagnostic and treatment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103866017B (zh) * 2005-08-01 2016-05-25 俄亥俄州立大学研究基金会 用于乳腺癌的诊断、预后和治疗的基于MicroRNA的方法和组合物
EP2280078B1 (en) * 2008-03-27 2016-05-18 Kuroda, Masahiko Marker for determination of breast cancer, test method, and test kit

Also Published As

Publication number Publication date
BR112016005413A8 (pt) 2018-04-03
WO2015035480A1 (pt) 2015-03-19

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: FUNDACAO PIO XII (BR/SP) , FUNDACAO DE AMPARO A PE

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements