BR112015026516A2 - agentes antibacterianos de fenicol inovadores - Google Patents

agentes antibacterianos de fenicol inovadores

Info

Publication number
BR112015026516A2
BR112015026516A2 BR112015026516A BR112015026516A BR112015026516A2 BR 112015026516 A2 BR112015026516 A2 BR 112015026516A2 BR 112015026516 A BR112015026516 A BR 112015026516A BR 112015026516 A BR112015026516 A BR 112015026516A BR 112015026516 A2 BR112015026516 A2 BR 112015026516A2
Authority
BR
Brazil
Prior art keywords
fenicol
innovative
antibacterial agents
compounds
abstract
Prior art date
Application number
BR112015026516A
Other languages
English (en)
Other versions
BR112015026516B1 (pt
Inventor
Vairagounda Rajendran
Andrew Ewin Richard
Johnson Timothy
Original Assignee
Zoetis Services Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Services Llc filed Critical Zoetis Services Llc
Publication of BR112015026516A2 publication Critical patent/BR112015026516A2/pt
Publication of BR112015026516B1 publication Critical patent/BR112015026516B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
    • C07C381/10—Compounds containing sulfur atoms doubly-bound to nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56—Amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C07D213/71—Sulfur atoms to which a second hetero atom is attached
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

resumo “agentes antibacterianos de fenicol inovadores” a presente invenção fornece derivados de fenicol inovadores, seu uso para o tratamento de infecções em mamíferos, composições farmacêuticas que contêm esses compostos inovadores e métodos para a preparação desses compostos.
BR112015026516-2A 2013-04-17 2014-04-16 Compostos derivados de fenicol, composição farmacêutica compreendendo os mesmos e uso dos ditos compostos para o controle ou tratamento de infecções em gado BR112015026516B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361812869P 2013-04-17 2013-04-17
US61/812,869 2013-04-17
PCT/US2014/034336 WO2014172443A1 (en) 2013-04-17 2014-04-16 Novel phenicol antibacterial agents

Publications (2)

Publication Number Publication Date
BR112015026516A2 true BR112015026516A2 (pt) 2017-07-25
BR112015026516B1 BR112015026516B1 (pt) 2021-08-10

Family

ID=50933491

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015026516-2A BR112015026516B1 (pt) 2013-04-17 2014-04-16 Compostos derivados de fenicol, composição farmacêutica compreendendo os mesmos e uso dos ditos compostos para o controle ou tratamento de infecções em gado

Country Status (19)

Country Link
US (1) US9422236B2 (pt)
EP (1) EP2986592B1 (pt)
JP (1) JP6125096B2 (pt)
CN (1) CN105121406B (pt)
AR (1) AR095893A1 (pt)
AU (1) AU2014253985B2 (pt)
BR (1) BR112015026516B1 (pt)
CA (1) CA2908524C (pt)
DK (1) DK2986592T3 (pt)
ES (1) ES2665915T3 (pt)
HK (1) HK1220684A1 (pt)
HR (1) HRP20180442T1 (pt)
HU (1) HUE036671T2 (pt)
LT (1) LT2986592T (pt)
MX (1) MX360040B (pt)
PL (1) PL2986592T3 (pt)
PT (1) PT2986592T (pt)
TW (1) TWI508940B (pt)
WO (1) WO2014172443A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019105871A1 (de) 2017-11-29 2019-06-06 Bayer Aktiengesellschaft Stickstoffhaltige heterocyclen als schädlingsbekämpfungsmittel
BR112021005584A2 (pt) 2018-09-24 2021-06-29 Zoetis Services Llc processo para preparar o composto 2,2-difluoro-n-((1r,2s-3-fluoro-1-hidróxi-1-(4-(6-(s-metilsulfonimidoil)piridin-3-il)fenil)propan-2-il)acetamida

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235892A (en) * 1979-02-05 1980-11-25 Schering Corporation, Patent Dept. 1-Aryl-2-acylamido-3-fluoro-1-propanols, methods for their use as antibacterial agents and compositions useful therefor
WO2003077828A2 (en) * 2002-03-08 2003-09-25 Schering-Plough, Ltd. Novel florfenicol-type antibiotics
WO2012125832A2 (en) * 2011-03-15 2012-09-20 Rib-X Pharmaceuticals, Inc. Antimicrobial agents

Also Published As

Publication number Publication date
AU2014253985B2 (en) 2017-03-30
AR095893A1 (es) 2015-11-18
TWI508940B (zh) 2015-11-21
BR112015026516B1 (pt) 2021-08-10
DK2986592T3 (en) 2018-04-16
HUE036671T2 (hu) 2018-07-30
EP2986592B1 (en) 2018-01-31
CA2908524A1 (en) 2014-10-23
CA2908524C (en) 2017-05-09
US9422236B2 (en) 2016-08-23
AU2014253985A1 (en) 2015-10-08
MX360040B (es) 2018-10-18
CN105121406A (zh) 2015-12-02
PT2986592T (pt) 2018-04-19
JP6125096B2 (ja) 2017-05-10
PL2986592T3 (pl) 2018-07-31
MX2015014657A (es) 2016-06-02
LT2986592T (lt) 2018-05-10
US20160075647A1 (en) 2016-03-17
TW201444789A (zh) 2014-12-01
JP2016516822A (ja) 2016-06-09
HK1220684A1 (zh) 2017-05-12
ES2665915T3 (es) 2018-04-30
WO2014172443A1 (en) 2014-10-23
EP2986592A1 (en) 2016-02-24
HRP20180442T1 (hr) 2018-04-20
CN105121406B (zh) 2017-08-22

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Legal Events

Date Code Title Description
B25G Requested change of headquarter approved

Owner name: ZOETIS SERVICES LLC (US)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]

Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO POR NAO SE ENQUADRAR NO ART. 229-C DA LPI.

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Notification to applicant to reply to the report for non-patentability or inadequacy of the application [chapter 6.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 16/04/2014, OBSERVADAS AS CONDICOES LEGAIS.