BR112015001463A2 - método para a produção de microveículos - Google Patents
método para a produção de microveículosInfo
- Publication number
- BR112015001463A2 BR112015001463A2 BR112015001463A BR112015001463A BR112015001463A2 BR 112015001463 A2 BR112015001463 A2 BR 112015001463A2 BR 112015001463 A BR112015001463 A BR 112015001463A BR 112015001463 A BR112015001463 A BR 112015001463A BR 112015001463 A2 BR112015001463 A2 BR 112015001463A2
- Authority
- BR
- Brazil
- Prior art keywords
- layer
- micro vehicles
- vehicles
- production
- micro
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 238000000151 deposition Methods 0.000 abstract 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
- B81C1/00—Manufacture or treatment of devices or systems in or on a substrate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01G—CAPACITORS; CAPACITORS, RECTIFIERS, DETECTORS, SWITCHING DEVICES, LIGHT-SENSITIVE OR TEMPERATURE-SENSITIVE DEVICES OF THE ELECTROLYTIC TYPE
- H01G13/00—Apparatus specially adapted for manufacturing capacitors; Processes specially adapted for manufacturing capacitors not provided for in groups H01G4/00 - H01G11/00
- H01G13/06—Apparatus specially adapted for manufacturing capacitors; Processes specially adapted for manufacturing capacitors not provided for in groups H01G4/00 - H01G11/00 with provision for removing metal surfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/54—Labware with identification means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/54—Labware with identification means
- B01L3/545—Labware with identification means for laboratory containers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
- B81C99/00—Subject matter not provided for in other groups of this subclass
- B81C99/0075—Manufacture of substrate-free structures
- B81C99/008—Manufacture of substrate-free structures separating the processed structure from a mother substrate
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/005—Beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00502—Particles of irregular geometry
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
- B01J2219/00536—Sheets in the shape of disks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00554—Physical means
- B01J2219/00556—Perforations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00632—Introduction of reactive groups to the surface
- B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/12—Specific details about manufacturing devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0803—Disc shape
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0819—Microarrays; Biochips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0851—Bottom walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
- B81B2201/00—Specific applications of microelectromechanical systems
- B81B2201/05—Microfluidics
- B81B2201/058—Microfluidics not provided for in B81B2201/051 - B81B2201/054
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B81—MICROSTRUCTURAL TECHNOLOGY
- B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
- B81B2201/00—Specific applications of microelectromechanical systems
- B81B2201/06—Bio-MEMS
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Dispersion Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Manufacturing & Machinery (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Fluid Mechanics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Power Engineering (AREA)
- Micromachines (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
resumo patente de invenção: "método para a produção de microveículos". a presente invenção refere-se a um método para a produção de microveículos que compreende as etapas a seguir: (a) fornecer uma pastilha (6) que tem uma estrutura de sanduíche que compreende uma camada de fundo (7), uma camada de topo (8) e uma camada isolante (9) localizada entre as ditas camadas de fundo e de topo (7, 8), (b) gravar fora a camada de topo (8) para delinear as paredes laterais (12) dos corpos (11) dos microveículos, (c) depositar uma primeira camada ativa (13), pelo menos sobre uma superfície de topo (14) dos corpos (11), (d) aplicação de uma camada contínua de polímero (16) sobre a primeira camada ativa (13), (e) condicionamento de distância da camada de fundo (7) e a camada isolante (9), (f) a remoção da camada de polímero (16) para libertar os microveículos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12177718.9A EP2690059A1 (en) | 2012-07-24 | 2012-07-24 | Method for producing microcarriers |
PCT/EP2013/065442 WO2014016262A1 (en) | 2012-07-24 | 2013-07-22 | Method for producing microcarriers |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015001463A2 true BR112015001463A2 (pt) | 2017-07-04 |
Family
ID=48808369
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015001463A BR112015001463A2 (pt) | 2012-07-24 | 2013-07-22 | método para a produção de microveículos |
Country Status (13)
Country | Link |
---|---|
US (1) | US9349545B2 (pt) |
EP (2) | EP2690059A1 (pt) |
JP (1) | JP6277188B2 (pt) |
KR (1) | KR20150040939A (pt) |
CN (1) | CN104736470B (pt) |
AU (1) | AU2013295081B2 (pt) |
BR (1) | BR112015001463A2 (pt) |
CA (1) | CA2879150C (pt) |
ES (1) | ES2787857T3 (pt) |
IN (1) | IN2015DN00439A (pt) |
RU (1) | RU2631526C2 (pt) |
WO (1) | WO2014016262A1 (pt) |
ZA (1) | ZA201500438B (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2690058A1 (en) * | 2012-07-24 | 2014-01-29 | Biocartis SA | Method for producing microcarriers and for performing biological assays |
US9978644B1 (en) * | 2016-09-07 | 2018-05-22 | Amkor Technology, Inc. | Semiconductor device and manufacturing method |
KR102348180B1 (ko) | 2019-02-19 | 2022-01-07 | 전남대학교산학협력단 | 색전술용 마이크로캐리어 및 그 제조방법 |
CN110484129B (zh) * | 2019-07-02 | 2022-01-25 | 昆山联滔电子有限公司 | 带有防护涂层的产品及其制备方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5071792A (en) * | 1990-11-05 | 1991-12-10 | Harris Corporation | Process for forming extremely thin integrated circuit dice |
US5545291A (en) * | 1993-12-17 | 1996-08-13 | The Regents Of The University Of California | Method for fabricating self-assembling microstructures |
KR100660600B1 (ko) | 1999-04-16 | 2006-12-22 | 티보텍 엔.브이. | 미세담체의 코딩 |
US6963530B1 (en) * | 2000-02-01 | 2005-11-08 | Research Investment Network, Inc. | Near-field optical head system with integrated slider and laser |
TWI220927B (en) * | 2000-05-12 | 2004-09-11 | Rong-Seng Chang | Method for producing a micro-carrier |
US6823744B2 (en) * | 2002-01-11 | 2004-11-30 | Honda Giken Kogyo Kabushiki Kaisha | Six-axis force sensor |
US7872804B2 (en) * | 2002-08-20 | 2011-01-18 | Illumina, Inc. | Encoded particle having a grating with variations in the refractive index |
JP2004349416A (ja) * | 2003-05-21 | 2004-12-09 | Nikon Corp | Memsの製造方法 |
US7951580B2 (en) * | 2004-04-21 | 2011-05-31 | The Regents Of The University Of California | Automated, programmable, high throughput, multiplexed assay system for cellular and biological assays |
US7507638B2 (en) * | 2004-06-30 | 2009-03-24 | Freescale Semiconductor, Inc. | Ultra-thin die and method of fabricating same |
US7829440B2 (en) * | 2006-08-07 | 2010-11-09 | Semileds Optoelectronics Co. Ltd. | Method of separating semiconductor dies |
CN102083575B (zh) * | 2007-06-25 | 2014-09-17 | 阿费梅特里克斯公司 | 刻印的微码 |
US8097926B2 (en) * | 2008-10-07 | 2012-01-17 | Mc10, Inc. | Systems, methods, and devices having stretchable integrated circuitry for sensing and delivering therapy |
CA2745580C (en) * | 2008-12-23 | 2017-11-07 | Biocartis Sa | Assay device and method for performing biological assays |
WO2010134019A2 (en) * | 2009-05-19 | 2010-11-25 | Ramot At Tel Aviv University Ltd. | Vertical junction pv cells |
EP2312393A1 (en) | 2009-10-14 | 2011-04-20 | Biocartis SA | Method for producing microparticles |
US8953314B1 (en) * | 2010-08-09 | 2015-02-10 | Georgia Tech Research Corporation | Passive heat sink for dynamic thermal management of hot spots |
-
2012
- 2012-07-24 EP EP12177718.9A patent/EP2690059A1/en not_active Withdrawn
-
2013
- 2013-07-22 KR KR20157004439A patent/KR20150040939A/ko not_active Application Discontinuation
- 2013-07-22 CA CA2879150A patent/CA2879150C/en not_active Expired - Fee Related
- 2013-07-22 RU RU2015101761A patent/RU2631526C2/ru not_active IP Right Cessation
- 2013-07-22 BR BR112015001463A patent/BR112015001463A2/pt not_active Application Discontinuation
- 2013-07-22 WO PCT/EP2013/065442 patent/WO2014016262A1/en active Application Filing
- 2013-07-22 CN CN201380049104.5A patent/CN104736470B/zh not_active Expired - Fee Related
- 2013-07-22 JP JP2015523519A patent/JP6277188B2/ja not_active Expired - Fee Related
- 2013-07-22 EP EP13739449.0A patent/EP2877423B1/en active Active
- 2013-07-22 AU AU2013295081A patent/AU2013295081B2/en not_active Ceased
- 2013-07-22 US US14/414,174 patent/US9349545B2/en not_active Expired - Fee Related
- 2013-07-22 ES ES13739449T patent/ES2787857T3/es active Active
-
2015
- 2015-01-19 IN IN439DEN2015 patent/IN2015DN00439A/en unknown
- 2015-01-21 ZA ZA2015/00438A patent/ZA201500438B/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU2013295081B2 (en) | 2016-10-06 |
RU2631526C2 (ru) | 2017-09-25 |
US9349545B2 (en) | 2016-05-24 |
EP2690059A1 (en) | 2014-01-29 |
CA2879150C (en) | 2020-07-14 |
CN104736470A (zh) | 2015-06-24 |
RU2015101761A (ru) | 2016-08-10 |
EP2877423B1 (en) | 2020-03-11 |
WO2014016262A1 (en) | 2014-01-30 |
EP2877423A1 (en) | 2015-06-03 |
AU2013295081A1 (en) | 2015-02-05 |
CA2879150A1 (en) | 2014-01-30 |
JP6277188B2 (ja) | 2018-02-07 |
IN2015DN00439A (pt) | 2015-06-19 |
KR20150040939A (ko) | 2015-04-15 |
ES2787857T3 (es) | 2020-10-19 |
CN104736470B (zh) | 2016-08-17 |
US20150162141A1 (en) | 2015-06-11 |
ZA201500438B (en) | 2017-11-29 |
JP2015531691A (ja) | 2015-11-05 |
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